A novel ratiometric BenzoBODIPY-Based fluorescent probe for the detection and imaging of Cysteine in living cells and zebrafish models DOI

Jiangming Fan,

Bin Lin,

Shuqi Tang

et al.

Talanta, Journal Year: 2024, Volume and Issue: 285, P. 127332 - 127332

Published: Dec. 5, 2024

Language: Английский

Medium-dependent selectivity for Cu2+ and glutathione by a near-infrared fluorescent probe DOI
Kaiqiang Zhang,

Baijun Zhao,

Yanxi Song

et al.

Journal of Photochemistry and Photobiology A Chemistry, Journal Year: 2024, Volume and Issue: 453, P. 115683 - 115683

Published: April 17, 2024

Language: Английский

Citations

3
Boron‐Salphen Conjugate based Molecular Probe Exhibiting Fluorescence On‐Off‐On Response in Detection of Cu2+ and ATP through Displacement Approach DOI

Rimpi Bhandari,

Ravisen Rai,

Mohammed Kaleem

et al.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: 19(15)

Published: May 22, 2024

Synthesis and photophysical properties of a fluorescent probe HBD is described. Probe upon interaction with metal ions, anions nucleoside pyrophosphates (NPPs) showed fluorescence quenching Cu

Language: Английский

Citations

3
Simple, rapid and enzyme-free assay for potentiometric determination of L-cysteine based on meso-2,3-dimercaptosuccinic acid self-assembled gold electrode DOI
Yuanqing Wu,

Hong-Shu Xiao,

Yu‐Yu Peng

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: 206, P. 111548 - 111548

Published: Aug. 31, 2024

Language: Английский

Citations

3
Theoretical Investigation of a Coumarin Fluorescent Probe for Distinguishing the Detection of Small-Molecule Biothiols DOI Creative Commons
Yue Deng, He Huang, Jian Feng

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(3), P. 554 - 554

Published: Jan. 23, 2024

Monitoring the level of biothiols in organisms would be beneficial for health inspections. Recently, 3-(2′-nitro vinyl)-4-phenylselenyl coumarin as a fluorescent probe distinguishing detection small-molecule cysteine/homocysteine (Cys/Hcy) and glutathione (GSH) was developed. By introducing 4-phenyselenium active site, CouSeNO2/CouSNO2 capable detecting Cys/Hcy GSH dual fluorescence channels. Theoretical insights into sensing mechanism were provided this work. The details electron excitation process products under optical character analyzed using quantum mechanical method. All these theoretical results provide insight pave way molecular design probes biothiols.

Language: Английский

Citations

2
Fluorescent Probes for Cysteine and Cysteine Oxidation Imaging DOI
Xia Zhang, Guocheng Li, Wei Pan

et al.

Chemical Research in Chinese Universities, Journal Year: 2024, Volume and Issue: 40(2), P. 225 - 236

Published: Feb. 28, 2024

Language: Английский

Citations

2
A selective mitochondria-targeted fluorescent probe for imaging cysteine in drug-induced liver injury DOI
Guixin Qin,

Lingli Gao,

Nan Yin

et al.

Talanta, Journal Year: 2024, Volume and Issue: 282, P. 127056 - 127056

Published: Oct. 16, 2024

Language: Английский

Citations

2
An interesting aggregation induced red shifted emissive and ESIPT active hydroxycoumarin tagged symmetrical azine: Colorimetric and fluorescent turn on–off–on response towards Cu2+ and Cysteine, real sample analysis and logic gate application DOI
Moorthy Mathivanan, J.G. Małecki, Balasubramanian Murugesapandian

et al.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 326, P. 125270 - 125270

Published: Oct. 12, 2024

Language: Английский

Citations

1
Advances in the synthesis and applications of macrocyclic polyamines DOI Creative Commons
Yongguang Gao,

Li-Na Guo,

Xinhua Liu

et al.

Royal Society Open Science, Journal Year: 2024, Volume and Issue: 11(6)

Published: June 1, 2024

Macrocyclic polyamines constitute a significant class of macrocyclic compounds that play pivotal role in the realm supramolecular chemistry. They find extensive applications across diverse domains including industrial and agricultural production, clinical diagnostics, environmental protection other multidisciplinary fields. possess distinctive cavity structure with varying sizes, depths, electron-richness degrees flexibilities. This unique feature enables them to form specific structures through complexation objects, thereby attracting considerable attention from chemists, biologists materials scientists alike. However, there is currently lack comprehensive summaries on synthesis methods for polyamines. In this review article, we provide an in-depth introduction while analysing their respective advantages disadvantages. Furthermore, also present overview recent 5-year advancements using as non-viral gene vectors, fluorescent probes, diagnostic therapeutic reagents well catalysts. Looking ahead future research directions application various fields will hopefully inspire new ideas use.

Language: Английский

Citations

0
Pretheranostic agents with extraordinaryNIRF/photoacoustic imaging performanceand photothermal oncotherapy efficacy DOI Creative Commons
Shi Liu, Zhenzhou Chen, Jiaxin Ou

et al.

Acta Pharmaceutica Sinica B, Journal Year: 2024, Volume and Issue: 14(12), P. 5370 - 5381

Published: July 24, 2024

Cervical cancer, the most common gynecological malignancy, significantly and adversely affects women's physical health well-being. Traditional surgical interventions chemotherapy, while potentially effective, often entail serious side effects that have led to an urgent need for novel therapeutic methods. Photothermal therapy (PTT) has emerged as a promising approach due its ability minimize damage healthy tissue. Connecting biothiol detection group PTT-sensitive molecules can improve tumor targeting further potential effects. In this study, we developed near-infrared fluorescence (NIRF)/photoacoustic (PA) dual-mode probe, S-NBD, which demonstrated robust PTT performance. This innovative probe is capable of activating NIRF/PA signals enable biothiols with high emission wavelength (838 nm) large Stokes shift (178 nm), allowing in vivo monitoring cancer cells. Additionally, achieved outstanding photothermal conversion efficiency 67.1%. The application laser irradiation (660 nm, 1.0 W/cm2, 5 min) was able achieve complete ablation without recurrence. summary, seminal study presents pioneering dicyanoisophorone-based imaging, incorporating features from first time. achieves dual objectives improving diagnosis treatment.

Language: Английский

Citations

0
A Hydrogen Bonded Non‐Porous Organic‐Inorganic Framework for Measuring Cysteine in Blood Plasma and Endogenous Cancer Cell DOI Open Access
Riya Ghosh,

Debjani Pradhan,

Snehasish Debnath

et al.

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 20, 2024

An imbalance in cysteine (Cys) levels the cells and plasma has been identified as risk indicator for various human diseases. The structural similarity of with its congener homocysteine glutathione offers challenges measurement. Herein, we report a hydrogen-bonded organic-inorganic framework Cu(II) (HOIF) selective detection over other biothiols. non-fluorescent HOIF showed 12-fold green emission presence cysteine. monomeric unit is stabilized via intermolecular hydrogen bonds, resulting non-porous network structure. Non-interference from homocysteine, glutathione, competitive bio-analytes revealed explicit affinity Fluorimetric titration wide working concentration window (650 nM-800 μM) measuring an aqueous medium. mechanistic investigation involving HRMS, EPR, UV-vis spectroscopic studies decomplexation Cys, fluorescence turn-on response luminescent ligand. Validation using commercial dye, "Cysteine Green", confirmed prospect early diagnostic purposes. Utilizing property cysteine, measured quantitatively blood samples. Bio-imaging endogenous cancer indicated ability to monitor intracellular

Language: Английский

Citations

0