Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

Perfluorooctanoic acid (PFOA), a prominent member of the per- and polyfluoroalkyl substance (PFAS) family, has emerged as new perpetual pollutant posing significant environmental health risks, necessitating developing highly selective materials for its sensitive detection in water. In this work, we developed an electroactive fluorine-functionalized Cu-MOF (F-Cu-NH2BDC) through postmodification copper-2-amino-terephthalic (Cu-NH2BDC) MOF with 2,3,5,6-tetrafluoroterephthalaldehyde (TFTA). Experimental computational results suggested that F-F interactions between decorated tetrafluorobenzaldehyde groups PFOA, well among PFOA molecules themselves, would induce self-aggregation on surfaces or pores F-Cu-NH2BDC. This specific aggregation inhibited contact electron transfer F-Cu-NH2BDC electrolyte, resulting decrease inherent electrochemical Cu2+/Cu+ redox signal from Based this, F-Cu-NH2BDC-based label- probe-free sensor was exploited excellent linear range 5 pM to 500 μM extremely low limit 3.54 pM, surpassing most currently reported nonelectrochemical PFAS sensors. also exhibited good stability, reproducibility, anti-interference performance, enabling accurate measurement concentrations actual commercial drinking These findings shed light design sensors utilizing interaction working mechanism.

Language: Английский