Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: unknown, P. 110652 - 110652
Published: Nov. 1, 2024
Language: Английский
Industrial & Engineering Chemistry Research, Journal Year: 2025, Volume and Issue: 64(4), P. 1907 - 1932
Published: Jan. 14, 2025
Metal–organic frameworks (MOFs) have been shown to be great alternatives traditional porous materials in various chemical applications, and they very widely studied for biomedical applications the past decade specifically drug storage. After our review published 2011 [Keskin Kızılel, Ind. Eng. Chem. Res. 2011, 50 (4), 1799–1812, 10.1021/ie101312k], we witnessed a fast growth not only number variety of MOFs but also their usage across broad spectrum fields. With recent integration molecular modeling data science approaches experimental studies, significantly accelerated positioning them as pivotal components regenerative medicine, medical imaging, diagnostics. In this review, visited diverse considering computational efforts on storage delivery, bioimaging, biosensing. We focused underlying mechanisms governing interactions between biological systems discussed both opportunities challenges field highlight potential advanced therapeutics cancer neurological diseases.
Language: Английский
Citations
1
Advanced Composites and Hybrid Materials, Journal Year: 2025, Volume and Issue: 8(1)
Published: Jan. 18, 2025
Language: Английский
Citations
1
Accounts of Chemical Research, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 2, 2025
ConspectusChiral metal-organic frameworks (MOFs) are promising candidates as luminescent sensing materials for chiral species, which essential components in modern industries, pharmaceuticals, and biological processes. The discrimination of enantiomers with highly similar physical chemical properties is crucial because they often present concurrently the same system but may feature distinct effects on living matters. While rapid precise capabilities MOFs outshine traditional detection methods species daily life, production, natural environment, it requires well-matched electronic structures between species. Yet, conventional strategies to construct immensely challenging due crystallization difficulties based low-symmetric building blocks.Recent advancements MOF chemistry have led novel pathways synthesizing enantioselective sensing. Compared direct synthesis using optically pure ligands, usually complex costly, indirect has garnered significant attention reduced costs, simplified synthesis, enhanced material stability, broad application scope. In past few years, our group developed guest ion exchange, coordination modification, defect engineering indirectly MOFs. exchange cost-effective introducing ions into pores can be applied only charged frameworks. addition, also faces limitations availability tendency toward chirality loss during process. Besides, compared modification maintain stability stronger bonds. Still, accessible open metal sites that bind disordered dangling molecules, complicating structural determination. Therefore, specific such linker installation dual-end been afford well-defined crystal structures. all aforementioned decrease MOFs' pore sizes a certain degree, we further approach enlarge size introduce center simultaneously. Such competitive strategy facile low-cost expanded many well-known stable MOFs.In this Account, delve intricate evolution constructing tailored applications. We provide detailed analysis progression innovation within field, tracing development MOF-based luminescence sensors. By systematically reviewing various synthetic approaches, work highlights their respective strengths limitations. Beyond state art, Account offers forward-looking insights aiming inspire design next-generation These advanced hold promise versatile impactful applications across beyond.
Language: Английский
Citations
1
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160371 - 160371
Published: Feb. 1, 2025
Language: Английский
Citations
1
Materials Today Communications, Journal Year: 2025, Volume and Issue: unknown, P. 111966 - 111966
Published: Feb. 1, 2025
Language: Английский
Citations
1
Inorganic Chemistry Frontiers, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
The MOF/polymer electrolyte integrates flame retardancy and electrochemical performance via UiO-66 encapsulated HCCP strategy, effectively suppressing lithium dendrites delivering superior long-cycle stability rate in batteries.
Language: Английский
Citations
0
Small Methods, Journal Year: 2025, Volume and Issue: unknown
Published: April 14, 2025
Abstract Metal–organic frameworks, which are the desired candidates for biosensing application due to their tunable properties, significantly hindered by rapid degradation in aqueous solutions, as well loss of inherent fluorescence. Most studies aim improve hydrophobicity materials modifying contact angle, thereby enhancing water stability. However, droplets poorly adhere surface hydrophobic materials, limiting direct and detection environments. Drawing inspiration from sacrificial protection mechanism butterfly wings used evade predation entanglement, a universal approach is successfully developed protect water‐sensitive MIL‐MOFs molecule attack while preserving good hydrophilicity. Using organic ligand 2,2′‐bipyridine‐5,5′‐dicarboxylic acid (bpydc) scales, MIL‐125‐NH 2 ‐bpydc demonstrated broad pH structural stability (pH 2–12) fluorescence increased 10.17 time achieving highest performance MILMOFs. The biocompatible enabling it perform long‐term imaging living cells zebrafish, further detecting hydrogen sulfide (H S) biological systems via turn‐on emission. This study offers novel sacrifice‐protection strategy design development luminescent MOFs tailored applications.
Language: Английский
Citations
0
Inorganic Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: April 30, 2025
Capturing kinetic intermediates is crucial for understanding the formation mechanism of metal-organic frameworks (MOFs), but it particularly challenging metal phosphonate frameworks. Here, we employ a modulator-based strategy to control crystallization MOFs. By adding chelating ligand shikimic acid, obtained three-dimensional (3D) lanthanide-diphosphonate frameworks, [Ln2(amp2H2)3(H2O)x]·4H2O (Ln-3D, x = 6, Ln Sm, Eu, Gd, Tb, Ho; 4, Er), where amp2H4 prephotodimerized 9-anthracenemethylphosphonic acid. reducing reaction temperature from 90 70 °C, successfully isolated metastable intermediates, [Ln2(amp2H2)2(H2O)12](amp2H2)·10H2O (Ln-1D), with one-dimensional (1D) chain structures. The dianthracene moiety in linker amp2H22- confers additional dynamic features material due its potential dissociation into anthracene pairs and affects photophysical photochemical properties, which vary lanthanide ion. Moreover, labile coordinated water molecule Ho-3D releasable under X-ray irradiation at 300 K, whereas this responsiveness not obvious other Ln-3D (Ln Tb). This study only provides new case intermediate trapping also demonstrates rare materials ultraviolet (UV) light responsiveness.
Language: Английский
Citations
0
Nanomaterials, Journal Year: 2024, Volume and Issue: 14(17), P. 1379 - 1379
Published: Aug. 23, 2024
The blood–brain barrier (BBB) plays a vital role in safeguarding the central nervous system by selectively controlling movement of substances between bloodstream and brain, presenting substantial obstacle for administration therapeutic agents to brain. Recent breakthroughs nanoparticle-based delivery systems, particularly metal–organic frameworks (MOFs), provide promising solutions addressing BBB. MOFs have become valuable tools delivering medications brain with their ability efficiently load drugs, release them over time, modify surface properties. This review focuses on recent advancements molecular-based approaches treating disorders, such as glioblastoma multiforme, stroke, Parkinson’s disease, Alzheimer’s disease. paper highlights significant impact overcoming shortcomings conventional drug techniques provides insights future research field neurotherapeutics.
Language: Английский
Citations
3
Small, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 23, 2024
Abstract Metal‐organic frameworks (MOFs) hold significant promise in the realm of gas sensing. However, current understanding their sensing mechanisms remains limited. Furthermore, large‐scale fabrication MOFs is hampered by inadequate mechanical properties. These two challenges contribute to sluggish development MOF‐based gas‐sensing materials. In this review, selection metal ions and organic ligands for designing first presented, deepening interactions between different ions/organic target gases. Subsequently, typical interfacial synthesis strategies (gas‐solid, gas‐liquid, solid‐liquid interfaces) are provided, highlighting potential constructing MOF membranes on superhydrophobic and/or superhydrophilic substrates. Then, a multi‐scale structure design proposed, including multi‐dimensional membrane heterogeneous design, improve performance through enhanced mass transfer specific sieving. This strategy anticipated augment task‐specific capabilities materials complex environments. Finally, several key future research directions outlined with aim not only further investigate underlying principles but also achieve efficient detection gases amidst interfering elevated moisture levels.
Language: Английский
Citations
2