Advances of nanobody-based immunosensors for detecting food contaminants

Trends in Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown, P. 104871 - 104871

Published: Jan. 1, 2025

Language: Английский

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Advancements in magnetic nanomaterial-assisted sensitive detection of foodborne bacteria: Dual-recognition strategies, functionalities, and multiplexing applications

Food Chemistry, Journal Year: 2025, Volume and Issue: 478, P. 143626 - 143626

Published: Feb. 27, 2025

Language: Английский

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Multifunctional SERS Substrate for Simultaneous Detection of Multiple Contaminants and Photothermal Removal of Pathogenic Bacteria

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 13, 2024

In this work, a boric-acid-modified Fe

Language: Английский

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Multiplexed lateral-flow immunoassays for the simultaneous detection of several mycotoxins in foodstuffs

Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 156, P. 104858 - 104858

Published: Dec. 27, 2024

Language: Английский

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Monitoring the On-Surface Boronic Acid Condensation Process at the Nanoscale Using Tip-Enhanced Raman Spectroscopy

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 6, 2025

The on-surface condensation of boronic acids is a key step in fabricating functional interfaces with tailored properties; yet, clear understanding the molecular structural transformations involved remains significant challenge. Here, we directly monitor reaction self-assembled monolayer 4-mercaptophenylboronic acid (MPBA) on Au(111) using tip-enhanced Raman spectroscopy (TERS). evolution MPBA adlayer tracked via emergence new peaks, blue shifts, and intensity changes characteristic bands. Hyperspectral TERS imaging provides comprehensive insight into transformations, including B-O-B bond formation, increased constraints, an orientation. Furthermore, density theory simulations confirm that boroxine trimer primary product reaction. This study insights chemistry for rational design functionalized surfaces targeted chemical properties.

Language: Английский

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Development of boronate affinity adsorbent bearing -B(OH)2 and F groups with low pKa value for enhanced production and purification of lactulose through adsorption-assisted bio-isomerization of lactose

Food Chemistry, Journal Year: 2025, Volume and Issue: 479, P. 143779 - 143779

Published: March 8, 2025

Language: Английский

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Magnetic nanoprobe-enabled lateral flow assays in the applications of food safety and in vitro diagnostic

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 534, P. 216588 - 216588

Published: March 9, 2025

Language: Английский

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Formulations with Boric Acid or Aryl-Organoboron Compounds for Treating Diabetic Foot Ulcers

Scientia Pharmaceutica, Journal Year: 2025, Volume and Issue: 93(1), P. 14 - 14

Published: March 19, 2025

Boron-containing compounds (BCCs) have been proposed for the treatment of diabetes and its complications. Recent studies reported an improvement in design development pharmaceutical formulations (often gels) containing boric acid applied to foot ulcers humans diagnosed with diabetes. The mechanisms action include antimicrobial effects, modulation inflammation metabolism, induction cell differentiation. On other hand, recent suggested that boronic acids are potent antibacterial antifungal compounds, effective modulators inflammation, inducers vascular regeneration as well healing, they confer attractive properties such adhesion, interaction, formation complexes formulations. Moreover, only a handful conducted animals role some BCCs enhancers wound including their actions on induced and/or infected wounds disrupted metabolism. Also, it should be mentioned no strong interactions between present described. developed combination could act additive complementary therapy diabetic humans. Further required support hypothesis this acts through diverse improve healing while avoiding or limiting local disseminated infection. Furthermore, safety used established, these current protocols treating patients ulcers.

Language: Английский

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Highly selective and sensitive electrochemical detection of Escherichia coli O157:H7 using a bacteria-imprinted polymer and 3-aminophenylboronic acid-conjugated MnO2 nanozyme

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113588 - 113588

Published: April 1, 2025

Language: Английский

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One‐Pot Synthesis of Antibacterial and Antioxidant Self‐Healing Bioadhesives Using Ugi Four‐Component Reactions

Journal of Biomedical Materials Research Part B Applied Biomaterials, Journal Year: 2025, Volume and Issue: 113(5)

Published: May 1, 2025

ABSTRACT Bioadhesive materials are extensively utilized as alternatives to surgical sutures and wound dressings. Despite significant advancements in their synthesis, current bioadhesives suffer from inadequate mechanical stability, suboptimal wet tissue adhesion, a lack of inherent antibacterial antioxidant properties, while requiring multistep synthesis processes, complicating production for biomedical applications. To address these limitations, we developed new bioadhesive, named UgiGel, synthesized through one‐pot Ugi four‐component reaction (Ugi‐4CR). Our strategy gelatin the backbone, 4‐formylphenylboronic acid (4‐FPBA) an aldehyde source improved adhesion activity, gallic (GA) carboxylic activity healing, cyclohexyl isocyanide (CyIso) induce pseudopeptide structures. The internal crosslinking between GA 4‐FPBA via dynamic boronate ester bond formation, triggered by slight pH changes (7.4–7.8) temperature elevation (25°C–40°C), resulted formation viscoelastic self‐healing hydrogels with water only byproduct without need initiator/light activation. UgiGel showed higher porcine skin (139.8 ± 8.7 kPa) compared commercially available bioadhesives, Evicel (26.3 2.6 Coseal (19.3 9.9 kPa). It also demonstrated effective properties against both Gram‐negative Gram‐positive bacteria, well activity. Additionally, vitro studies using NIH‐3T3 cells confirmed biocompatibility over 7 days culture. Moreover, vivo biodegradation were subcutaneous implantation rats up 28 days. results that outperformed terms self‐healing, compromising or physical representing promising multifunctional bioadhesive sealing repair.

Language: Английский

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