Asian Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 11, 2025

Abstract Polymethine cyanine dyes have witnessed significant advancements in bioimaging and phototherapy due to their optical properties ease of modification. This review categorizes introduces typical synthesis Cy3, Cy5, Cy7 longer polymethine dyes, highlights organic‐specific in‐cell cyanines via the newly‐established pseudo‐trimerization method using a single exogenous precursor activatable by visible light, free radicals or reactive oxygen species. Further discussions delve into functionalization strategies structure‐activity relationships summarizes bioapplications fluorescence imaging, multimodal assisted diagnosis treatments, aiming unlock full potential scientific research clinical translation.

Language: Английский