Cyclodextrin based artificial enzymes

Sustainable Chemistry and Pharmacy, Journal Year: 2025, Volume and Issue: 44, P. 101945 - 101945

Published: Feb. 7, 2025

Language: Английский

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Detecting Changes in Singlet Oxygen and Viscosity during Apoptosis-Ferroptosis Mediated Photodynamic Therapy and Establishing Visual Imaging of Fatty Liver

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Cancer is a serious global health threat, and photodynamic therapy (PDT) an effective treatment method for cancer. This works by generating large amount of singlet oxygen (1O2) under the influence light, which induces apoptosis in tumor cells, leading to their destruction. However, resistance cells limits development PDT, thus combination ferroptosis provides new perspective PDT. During PDT ferroptosis, levels 1O2 microenvironment (viscosity) within often change. To address this, this study developed novel fluorescent probe, NI–QM-OH, based on TICT–ICT effect, capable monitoring changes viscosity during The probe exhibits excellent selectivity, high sensitivity, low LOD (0.38 μM), has been successfully applied bioimaging HepG2, HeLa, MCF-7 as well zebrafish. Most importantly, NI–QM–OH also enables visualization diagnosis fatty liver disease (both alcoholic nonalcoholic).

Language: Английский

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Advances on fluorescence bioimaging and photo-mediated therapy of NIR-II small molecule dyes

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 534, P. 216587 - 216587

Published: March 14, 2025

Language: Английский

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Self-assembled nanoprobes for cancer phototheranostics

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 538, P. 216643 - 216643

Published: April 18, 2025

Language: Английский

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