Regenerative Biomaterials,
Journal Year:
2023,
Volume and Issue:
11
Published: Dec. 23, 2023
Abstract
Metal–organic
frameworks
(MOFs)
have
a
high
specific
surface
area,
adjustable
pores
and
can
be
used
to
obtain
functional
porous
materials
with
diverse
well-ordered
structures
through
coordination
self-assembly,
which
has
intrigued
wide
interest
in
broad
range
of
disciplines.
In
the
arena
biomedical
engineering,
functionalized
modification
MOFs
produced
drug
carriers
excellent
dispersion
functionalities
such
as
target
delivery
response
release,
promising
applications
bio-detection,
disease
therapy,
tissue
healing,
other
areas.
This
review
summarizes
present
state
research
on
functionalization
by
physical
binding
or
chemical
cross-linking
small
molecules,
polymers,
biomacromolecules,
hydrogels
evaluates
role
approach
boosting
reactivity
materials.
On
this
basis,
application
composites
engineering
fields
delivery,
repair,
treatment,
bio-detection
imaging
is
surveyed,
development
trend
prospects
an
important
new
class
field
are
anticipated,
may
provide
some
inspiration
reference
for
further
MOF
bio-medical
applications.
