ChemBioChem,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 14, 2024
Abstract
Covalent
organic
frameworks
(COFs)
have
emerged
as
a
distinguished
class
of
porous
materials.
Owing
to
their
ability
be
constructed
through
covalent
bonds
involving
light
elements,
such
hydrogen,
boron,
carbon,
nitrogen,
and
oxygen,
COFs
offer
greater
stability
lower
cytotoxicity
than
metal–organic
do,
addressing
critical
limitations
in
vivo
applications.
Their
unique
attributes,
high
surface
area,
customizable
pore
sizes,
versatile
functionalities,
make
them
ideal
for
various
biomedical
This
review
aims
provide
an
overview
the
recent
advancements
modern
uses.
First,
variety
methods
synthesis
are
outlined,
which
ensures
suitability
medical
use.
Next,
we
delve
into
innovative
applications,
emphasizing
roles
disease
diagnosis
therapies.
Finally,
challenges,
clinical
translation,
biocompatibility,
controlled
drug
release,
critically
discussed,
providing
comprehensive
insight
potential
revolutionizing
technologies.
Overall,
this
offers
COFs’
capabilities
future
prospects
enhancing
Nanoscale,
Journal Year:
2023,
Volume and Issue:
16(3), P. 961 - 977
Published: Dec. 4, 2023
Covalent
organic
frameworks
(COF)
are
porous
crystalline
polymers
connected
by
covalent
bonds.
Due
to
their
inherent
high
specific
surface
area,
tunable
pore
size,
and
good
stability,
they
have
attracted
extensive
attention
from
researchers.
In
recent
years,
COF
membrane
materials
developed
rapidly,
a
large
amount
of
research
work
has
been
presented
on
the
preparation
methods,
properties,
applications
membranes.
This
review
focuses
independent/pure
continuous
First,
based
formation
mechanism,
methods
categorized
into
two
main
groups:
bottom-up
top-down.
Four
presented,
namely,
solvothermal,
interfacial
polymerization,
steam-assisted
conversion,
layer
layer.
Then,
aperture,
hydrophilicity/hydrophobicity
charge
properties
membranes
summarized
outlined.
According
application
directions
gas
separation,
water
treatment,
solvent
nanofiltration,
pervaporation
energy,
latest
results
presented.
Finally,
challenges
future
an
outlook
provided.
It
is
hoped
that
this
will
inspire
motivate
researchers
in
related
fields.
The
unsatisfactory
selectivity
of
reverse
osmosis
(RO)
membranes
toward
ammonium
poses
a
critical
challenge
in
water
safety
when
reclaiming
from
domestic
wastewater.
Herein,
we
developed
novel
integrated
electrochemical-assisted
RO
(ECRO)
system
using
the
electrically
treated
feed
spacer
and
permeate
carrier
as
electrodes.
This
enhanced
removal
efficiency
significantly
while
maintaining
low
energy
consumption,
increasing
94.36%
at
0
V
to
99.91%
4
V.
improvement
was
primarily
attributed
localized
oxidation
restricted
transport
ions.
Specifically,
anode
facilitated
indirect
through
active
chlorine
via
breakpoint
chlorination
pathway,
notably
on
side
prevent
damage
separation
layer
membrane
simultaneously
avoid
additional
chemical
additives.
Furthermore,
ion
responsible
for
its
improved
enthalpic
barrier,
evidenced
by
both
experimental
investigation
Monte
Carlo
simulation.
rise
barrier
driven
electric
field
force
across
membrane,
coupled
with
constrained
migration
near
surface
diffusion
within
membrane.
study
offers
new
insights
theoretical
foundation
optimization
electrochemistry
synergy
systems,
highlighting
potential
enhancing
wastewater
reclamation
green
low-energy
manner.
