Polymers for Advanced Technologies,
Journal Year:
2024,
Volume and Issue:
35(2)
Published: Feb. 1, 2024
Abstract
Metamaterials
are
specifically
designed
materials
that
possess
unique
properties
cannot
be
found
in
naturally
occurring
substances.
These
remarkable
have
the
capability
to
bring
about
a
significant
transformation
across
wide
range
of
industries.
Auxetic
structures
recent
area
research
distinctive
characteristic
known
as
negative
Poisson's
ratio.
Unlike
conventional
contract
when
stretched,
auxetic
actually
expand
two
dimensions.
In
this
study,
new
structure
was
introduced,
and
thermoplastic
polyurethane
samples
were
3D
printed
using
fused
filament
fabrication
method.
The
then
subjected
strains
ranging
from
5%
50%
ratios
measured
both
experimentally
numerically
finite
element
method
Ansys
software.
By
comparing
results
experimental
simulation,
it
is
evident
applying
within
causes
ratio
change
−0.81
−0.14
showed
newly
introduced
auxetic.
According
analysis
root
mean
square
error,
hexagonal
mesh
with
size
0.7
mm
consistently
produced
most
accurate
results,
aligning
closely
sample.
Given
an
entirely
novel
category
arrow‐head
structures,
there
potential
for
future
conducted
order
further
develop
enhance
model.
Journal of Biomaterials Applications,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 3, 2025
The
last
two
decaes
have
witnessed
significant
efforts
to
develop
gelatin/alginate
based
scaffolds
using
variants
of
3D
printing
techniques.
However,
their
biocompatibility
for
regenerating
complex
soft
tissues
remains
insufficiently
explored.
Addressing
this
gap,
we
fabricated
3D-printed
alginate-gelatin
(3A5G)
and
nanocellulose-reinforced
(3A5G1C)
hydrogel
with
clinically
relevant
dimensions
(15
mm
diameter,
5
height)
the
host
tissue
responses
were
critically
analyzed.
distinct
advantages
nanocellulose
in
modulating
mechanical
strength,
viscoelasticity,
swelling,
degradation
characteristics
established
our
prior
studies.
This
investigation
aimed
comprehensively
evaluate
foreign
body
response
these
a
rat
model.
animals
exhibited
healthy
metabolic
activity,
evidenced
by
progressive
weight
gain,
localized
healing,
normal
mobility
over
30
days.
Histological
analyses
could
not
reveal
any
adverse
immune
reaction
at
7-
or
30-days,
post-implantation.
Hematological
serum
biochemical
assessments
indicated
progression
from
acute
(7
days)
sub-acute
(30
inflammation,
following
subcutaneous
implantation,
without
signature
systemic
toxicity.
Immune
marker
evaluation
(TNF-α,
CD-8,
CD-68,
COX-2,
IL-6)
confirmed
absence
pathological
responses,
even
incorporation.
Immunohistochemical
analysis
CD31
staining
demonstrated
enhanced
vascularization
both
7
toxicity
scaffold
products
favorable
outcomes
underline
potential
regeneration.
incorporation
further
scaffolds'
functional
performance,
particularly
promoting
vascularization,
positioning
them
as
promising
candidates
engineering
applications.
Polymers for Advanced Technologies,
Journal Year:
2024,
Volume and Issue:
35(2)
Published: Feb. 1, 2024
Abstract
Metamaterials
are
specifically
designed
materials
that
possess
unique
properties
cannot
be
found
in
naturally
occurring
substances.
These
remarkable
have
the
capability
to
bring
about
a
significant
transformation
across
wide
range
of
industries.
Auxetic
structures
recent
area
research
distinctive
characteristic
known
as
negative
Poisson's
ratio.
Unlike
conventional
contract
when
stretched,
auxetic
actually
expand
two
dimensions.
In
this
study,
new
structure
was
introduced,
and
thermoplastic
polyurethane
samples
were
3D
printed
using
fused
filament
fabrication
method.
The
then
subjected
strains
ranging
from
5%
50%
ratios
measured
both
experimentally
numerically
finite
element
method
Ansys
software.
By
comparing
results
experimental
simulation,
it
is
evident
applying
within
causes
ratio
change
−0.81
−0.14
showed
newly
introduced
auxetic.
According
analysis
root
mean
square
error,
hexagonal
mesh
with
size
0.7
mm
consistently
produced
most
accurate
results,
aligning
closely
sample.
Given
an
entirely
novel
category
arrow‐head
structures,
there
potential
for
future
conducted
order
further
develop
enhance
model.