Regulating Supramolecular Assembly and Disassembly of Chitosan toward Efficiently Antibacterial Lubricous and Biodegradable Hydrogel Urinary Catheters

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 5, 2025

Abstract Urinary catheters serve as critical medical devices in clinical practice. However, the currently used urinary lack efficient antibacterial and lubricating properties, often leading to discomfort with patients even severe infections. Herein, a new strategy of supramolecular assembly disassembly chitosan (Cs) is developed that enables lubricous biodegradable hydrogel catheters. Sodium lauryl sulfonate (SLS) employed induce on surface Cs film strips an aqueous solution, resulting formation hollow Cs@SLS. Subsequent strong alkaline solution eliminates SLS component, yielding neat The mechanical strength these reaches 16 MPa, exceeding similar made plastics. are endowed high activity, capable inhibiting growth Staphylococcus aureus ( S. aureus), Escherichia coli E. coli) Proteus mirabilis(P. mirabilis) its surface, while bacteria found proliferate rapidly plastic within 24 h. They also demonstrate excellent lubricity, friction coefficient approaching zero, thus about 13 times lower than In vivo tests further confirm biodegradability catheters, highlighting their potential for applications.

Language: Английский

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Natural polysaccharides-based smart sensors for health monitoring, diagnosis and rehabilitation: A review

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 304, P. 140966 - 140966

Published: Feb. 12, 2025

Language: Английский

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3D Printing of Hydrogel Polysaccharides for Biomedical Applications: A Review

Biomedicines, Journal Year: 2025, Volume and Issue: 13(3), P. 731 - 731

Published: March 17, 2025

Additive manufacturing, also known as 3D printing, is becoming more and popular because of its wide range materials flexibility in design. Layer by layer, complex structures can be generated the revolutionary computer-aided process bioprinting. It particularly crucial for youngsters elderly patients a useful tool tailored pharmaceutical therapy. A lot research has been carried out recently on use polysaccharides matrices tissue engineering medication delivery. Still, there great need to create affordable, sustainable bioink with high-quality mechanical, viscoelastic, thermal properties well biocompatibility biodegradability. The primary biological substances (biopolymers) chosen formulation are proteins polysaccharides, among several resources utilized creation such structures. These naturally occurring biomaterials give macromolecular structure mechanical qualities (biomimicry), generally compatible tissues cells (biocompatibility), harmonious digesting processes (biodegradability). However, difficulty cell-laden printing technique (bioprinting) rheological characteristics these natural-based bioinks. Polysaccharides widely used they abundant reasonably priced natural polymers. Additionally, serve excipients formulations pharmaceuticals, nutraceuticals, cosmetics. remarkable benefits polysaccharides—biocompatibility, biodegradability, safety, non-immunogenicity, absence secondary pollution—make them ideal substrates. purpose this publication examine recent developments challenges related stimuli-responsive site-specific administration engineering.

Language: Английский

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Porous Sodium Carboxymethyl Starch Microspheres for Hemostasis and Skin Wound Healing

ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown

Published: April 3, 2025

An effective and rapid hemostatic material with flexible properties for clinical wound dressings is still an unmet need. Herein, a porous sodium carboxymethyl starch (CMS-Na-P) microsphere was successfully fabricated through polysaccharide fluffy aggregate (PSFA) technology facile low-cost process. CMS-Na-P exhibited water absorption capabilities alongside favorable cytocompatibility hemocompatibility. Additionally, could absorb red blood cells (RBCs), adhere to activate platelets, shorten clotting time in vitro. More importantly, its good vivo ability further demonstrated against hemorrhage rat liver tail, pig superficial skin, body vein, abdominal femoral artery. Meanwhile, full-thickness skin defect model, enhance healing accelerated epidermal regeneration collagen deposition. These make promising candidate treating bleeding wounds.

Language: Английский

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Enhanced carbon dispersion of polyacrylamide/sodium alginate hydrogels via irregular copolymerization imidazolyl ionic liquid for flexible sensor

Journal of Polymer Research, Journal Year: 2025, Volume and Issue: 32(4)

Published: April 1, 2025

Language: Английский

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Tailoring cellulose: from extraction and chemical modification to advanced industrial applications

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142950 - 142950

Published: April 1, 2025

Language: Английский

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Recent Progress in Cellulose-Based Conductive Hydrogels

Polymers, Journal Year: 2025, Volume and Issue: 17(8), P. 1089 - 1089

Published: April 17, 2025

Cellulose, a widely abundant natural polymer, is well recognized for its remarkable properties, such as biocompatibility, degradability, and mechanical strength. Conductive hydrogels, with their unique ability to conduct electricity, have attracted significant attention in various fields. The combination of cellulose conductive hydrogels has led the emergence cellulose-based which show great potential flexible electronics, biomedicine, energy storage. This review article comprehensively presents latest progress hydrogels. Firstly, it provides an in-depth overview cellulose, covering aspects like structure, diverse sources, classification. emphasizes cellulose’s role renewable versatile material. development applications different forms including delignified wood, bacterial nanocellulose, modified are elaborated. Subsequently, introduced, focus on network structures, single-network, interpenetrating network, semi-interpenetrating network. construction then discussed detail. includes forms, classified into electronic ionic key performance requirements, cost-effectiveness, property regulation, sensitive response environmental stimuli, self-healing ability, stable conductivity, multifunctionality. multiple areas also presented. In wearable sensors, they can effectively monitor human physiological signals real time. intelligent contribute wound healing, tissue engineering, nerve regeneration. supercapacitors, offer green sustainable gel electrolytes conventional batteries, help address critical issues lithium dendrite growth. Despite progress, there still challenges overcome. These include enhancing multifunctionality intelligence strengthening connection artificial intelligence, achieving simple, green, large-scale industrial production. Future research directions should center around exploring new synthesis methods, optimizing material expanding emerging fields, aiming promote widespread commercialization these materials.

Language: Английский

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Bacterial cellulose-based flexible phase change gel for potential release-controllable wound dressings

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 310, P. 143442 - 143442

Published: April 25, 2025

Language: Английский

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Three birds, one stone: A multifunctional POM-based ionic hydrogel integrating strain sensing, fluorescent and antibacterial properties

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 163257 - 163257

Published: April 1, 2025

Language: Английский

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Hydrogels composite optimized for low resistance and loading–unloading hysteresis for flexible biosensors

Journal of Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 671, P. 516 - 528

Published: May 24, 2024

Language: Английский

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