Soft Matter, Journal Year: 2024, Volume and Issue: 20(31), P. 6231 - 6246
Published: Jan. 1, 2024
By adapting existing bulk gelation protocols to droplet-based microfluidics, polyampholyte poly(dehydroalanine)-based microspheres were fabricated and evaluated regarding biomedical application.
Language: Английский
Nano Energy, Journal Year: 2025, Volume and Issue: unknown, P. 110805 - 110805
Published: Feb. 1, 2025
Language: Английский
Citations
2
Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 340, P. 122271 - 122271
Published: May 14, 2024
Language: Английский
Citations
5
Nature Electronics, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 3, 2024
Language: Английский
Citations
4
Advanced Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 22, 2024
Abstract Organic electrochemical synaptic transistors (OESTs), inspired by the biological nervous system, have garnered increasing attention due to their multifunctional applications in neuromorphic computing. However, practical implementation of OESTs for signal recognition—particularly those utilizing n‐type organic mixed ionic‐electronic conductors (OMIECs)—still faces significant challenges at hardware level. Here, a state‐of‐the‐art small‐molecule OEST integrated within physically simple and feasible reservoir‐computing (RC) framework temporal recognition is presented. This integration achieved leveraging adjustable properties n‐OEST, which exhibits tunable nonlinear short‐term memory, transitioning from volatility nonvolatility, demonstrating adaptive specificity. Additionally, nonvolatile offers 256 conductance levels wide dynamic range (≈147) long‐term potentiation/depression (LTP/LTD), surpassing previously reported n‐OESTs. By combining volatile n‐OESTs as reservoirs with single‐layer perceptron readout composed n‐OEST networks, this physical RC system achieves substantial accuracy both handwritten‐digit images (94.9%) spoken digit (90.7%), along ultrahigh weight efficiency. Furthermore, demonstrates outstanding (98.0%) grouped sleep monitoring, specifically snoring recognition. reliable pathway OMIEC‐driven computing presented advance bioinspired hardware‐based world.
Language: Английский
Citations
4
Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown
Published: April 10, 2025
Abstract Biological Field Effect Transistors (Bio‐FETs) are redefining the standard of biosensing by enabling label‐free, real‐time, and extremely sensitive detection biomolecules. At center this innovation is fundamental empowering role advanced materials, such as graphene, molybdenum disulfide, carbon nanotubes, silicon. These when harnessed with downstream biomolecular probes like aptamers, antibodies, enzymes, allow Bio‐FETs to offer unrivaled sensitivity precision. This review an exposition how advancements in materials science have permitted detect biomarkers low concentrations, from femtomolar attomolar levels, ensuring device stability reliability. Specifically, examines incorporation cutting‐edge architectures, flexible / stretchable multiplexed designs, expanding frontiers contributing development more adaptable user‐friendly Bio‐FET platforms. A key focus placed on synergy artificial intelligence (AI), Internet Things (IoT), sustainable approaches fast‐tracking toward transition research into practical healthcare applications. The also explores current challenges material reproducibility, operational durability, cost‐effectiveness. It outlines targeted strategies address these hurdles facilitate scalable manufacturing. By emphasizing transformative played their cementing position Bio‐FETs, positions a cornerstone technology for future solution precision would lead era where herald massive strides biomedical diagnostics subsume.
Language: Английский
Citations
0
Industrial Crops and Products, Journal Year: 2025, Volume and Issue: 229, P. 121018 - 121018
Published: April 11, 2025
Language: Английский
Citations
0
ACS Sensors, Journal Year: 2025, Volume and Issue: unknown
Published: April 27, 2025
Organic electrochemical transistor (OECT) sensors are a promising approach for point-of-care testing (POCT) thanks to their high sensitivity and ability operate in an aqueous environment. However, OECTs suffer from biological fouling at the gate channel interfaces when exposed complex samples. These nonspecific interactions can often obscure weak signal trace biomarker, compromising accuracy of measurements even leading false detection outcomes. In this study, we developed intrinsically antifouling OECT by modifying both with phosphorylcholine-functionalized poly(3,4-ethylenedioxythiophene) (PEDOT-PC). This modification notably enhances performance leveraging material's inherent mixed electron-ion conductivity, which increases transconductance decreases voltage. Additionally, zwitterionic nature device enables its ultrasensitive C-reactive protein (CRP) limit 0.11 pg/mL, mediated calcium ions. exceptional arises device's enhanced sense through simultaneously. Furthermore, sensor has demonstrated fastest sample-to-result time (≤60 s), making it highly suitable real-time CRP monitoring. Importantly, provides precise without interference proteins such as bovine serum albumin, fibrinogen, lysozyme, fetal serum. We envision offering robust biosensing platform rapid convenient biomarkers environments, providing reliable efficient solution POCT diagnostics.
Language: Английский
Citations
0
Chem & Bio Engineering, Journal Year: 2024, Volume and Issue: 1(6), P. 516 - 534
Published: June 14, 2024
Biofouling is a major issue across various industries ranging from healthcare to the production of food and water transportation. often induced or mediated by environmental microbes, such as bacteria. Therefore, developing antibacterial coatings has been an essential focus recent research on functional polymer thin films. To achieve high film quality, vapor-phase techniques represent promising alternatives traditional solution-based methods, especially for design synthesis coatings, they enable highly uniform, chemically precise, substrate-independent coatings. This Perspective examines potential polymerization create novel Current advancements in antifouling, bactericidal, antibiofilm, multifunctional via are organized based their action mechanisms principles. The opportunities challenges associated with implementing highlighted.
Language: Английский
Citations
3
Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 418, P. 136321 - 136321
Published: July 23, 2024
Language: Английский
Citations
3
Advanced Science, Journal Year: 2025, Volume and Issue: unknown
Published: March 24, 2025
Blood-contacting catheters are highly susceptible to thrombus formation, making heparin coating essential for reducing clinical complications. However, the limitations of coatings have spurred significant efforts develop alternative strategies. This study demonstrates a cost-efficient, mechanically viable, and universal zwitterion approach long complex with near-zero fouling, super anticoagulation, selective biocapturing. Leveraging synergistic action side groups, wet-adhesive initiator-bearing polymer rapidly assembles on catheter surfaces in aqueous environments, facilitating grafting superhydrophilic zwitterionic polymers onto inner walls. strategy broad adaptability, successfully applying ten substrates showing exceptional versatility modifying joints various shapes sizes. These exhibit protein fouling across pH range, superior resistance blood cells bacteria. Furthermore, they maintain excellent stability under simulated bloodstream without compromising anticoagulant performance. Beyond antifouling properties, this method enables construction bio-interaction networks walls, allowing precise capture circulating tumor from blood. technique, its rapid modification, robust customizable bio-functionality, provides an attractive solution for, beyond catheters, wide range medical devices that must perform challenging biological environments.
Language: Английский
Citations
0