Cuproptosis: an emerging domain for copper-based nanomaterials mediated cancer therapy DOI
Fan Zhao,

Zhuangzhuang Zhao,

Hao Gao

et al.

MedMat., Journal Year: 2024, Volume and Issue: 1(2), P. 74 - 94

Published: Dec. 1, 2024

Cuproptosis, a newly discovered copper-dependent mode of cell death, has received extensive attention in the field cancer therapy due to its specific activation pathway. Rapid accumulation large amounts copper ions within cells achieve overload is key activating cuproptosis. Advanced nanotechnology offers considerable promise for delivering cells, which copper-based nanomaterials have been proposed evoke cuproptosis-mediated therapy. However, it still great challenge induce specifically tumors and efficiently activate subsequent cuproptosis-related molecular pathways. Therefore, necessary summarize strategies used effectively or amplify cuproptosis based on currently developed nanomaterials, providing ideas design future. In this review, that can be are systematically classified selection. Subsequently, sensitization using provided therapeutic efficiency. Meanwhile, combination therapies maximizing treatment efficacy delineated. Ultimately, remaining challenges feasible future directions use tumor also discussed.

Language: Английский

Machine learning applications in nanomaterials: Recent advances and future perspectives DOI
Liang Yang, Hong Wang,

Deying Leng

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 156687 - 156687

Published: Oct. 1, 2024

Language: Английский

Citations

22
Recent advances on biomedical applications of zirconium-based Nanozymes: A review DOI
Mostafa Ghafori-Gorab,

Amir Kashtiaray,

Mahdi Karimi

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159464 - 159464

Published: Jan. 1, 2025

Language: Английский

Citations

1
Recent advances in nanomaterials and their mechanisms for infected wounds management DOI Creative Commons
Jianping Zhu, Fan Xia,

Shuaifei Wang

et al.

Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101553 - 101553

Published: Feb. 5, 2025

Wounds infected by bacteria pose a considerable challenge in the field of healthcare, particularly with increasing prevalence antibiotic-resistant pathogens. Traditional antibiotics often fail to achieve effective results due limited penetration, resistance development, and inadequate local concentration at wound sites. These limitations necessitate exploration alternative strategies that can overcome drawbacks conventional therapies. Nanomaterials have emerged as promising solution for tackling bacterial infections facilitating healing, thanks their distinct physicochemical characteristics multifunctional capabilities. This review highlights latest developments nanomaterials demonstrated enhanced antibacterial efficacy improved healing outcomes. The mechanisms are varied, including ion release, chemodynamic therapy, photothermal/photodynamic electrostatic interactions, delivery drugs, which not only combat but also address challenges posed biofilms antibiotic resistance. Furthermore, these create an optimal environment tissue regeneration, promoting faster closure. By leveraging unique attributes nanomaterials, there is significant opportunity revolutionize management wounds markedly improve patient

Language: Английский

Citations

1
Diversity of copper-containing nanoparticles and their influence on plant growth and development DOI
А. I. Perfileva, Б. Г. Сухов, Т. В. Конькова

et al.

Plant Physiology and Biochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 109575 - 109575

Published: Jan. 1, 2025

Language: Английский

Citations

0
Photo-responsive g-C3N4/copper molybdate nanocomposites enable laser-driven multi-modal imaging, photothermal and chemodynamic therapy for hepatocellular carcinoma treatment DOI

Kayalvizhi Samuvel Muthiah,

Sathan Raj Natarajan,

Selvaraj Jayaraman

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160751 - 160751

Published: Feb. 1, 2025

Language: Английский

Citations

0
Nanoparticulate Copper Cluster-Mediated Biosensing of Cardiac Biomolecular Markers DOI Creative Commons
Lakshmi V. Nair,

Jason B. Wheeler,

Young-Rock Ha

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(4), P. 237 - 237

Published: April 8, 2025

Being a leading cause of death, heart diseases across the globe need special attention to enable early diagnosis. Metal nanoparticle-mediated biosensors are useful clinical tools for detection bio-analytes. The size-dependent surface plasmon resonance (SPR) metal nanoparticles can be effectively utilized same purpose. evaluated by monitoring troponin level. A copper biosensor was developed through antibody conjugation I and T. nanosensor shows concentration-dependent SPR change towards T I.

Language: Английский

Citations

0
Nickel Tellurate Nanorods and Nanoparticles for the Oxygen Evolution Reaction DOI
Harishchandra Singh,

Miska Veijola-Kara,

Ekta Rani

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(11), P. 12480 - 12489

Published: May 22, 2024

Materials that lead to devices with tunable responses the morphology are a potential opportunity. Tellurium, growing material class possessing higher electronic conductivity, has recently been seen exhibit same in transition-metal-based complexes when combined toward wider energy applications. However, it rarely engineered and implemented for morphology-dependent low-dimensional (LD) structures catalytic reactions. Herein, first time, we provide novel approach designing dimension variable nano nickel tellurate (NTO), such as nanorods (NRs), through pH assisted anisotropic transformation from zero-dimensional amorphous counterpart. The resulting NRs have an average width of 5–30 nm lengths micrometers. Mechanistic studies show final product is determined by value used. In line structural phase analysis, core-level spectroscopic local spectro-microscopic determinations confirm formation Ni2+- Te4+/Te6+-based NTO via structure investigation covalency. Our study not only provides fresh achieve varied but also offers insights into growth reaction mechanisms transformation. proposed facile design scheme can be optimized synthesize any nanotellurates morphological purity promote reactions activity. As example, these samples were tested oxygen evolution reaction.

Language: Английский

Citations

1
A multifunctional hyaluronic acid-engineered mesoporous nanoreactor with H2O2/O2 self-sufficiency for pH-triggered endo-lysosomal escape and synergetic cancer therapy DOI
Fei Lu, Moon‐Sun Jang, Wei Jiang

et al.

Biomaterials Advances, Journal Year: 2024, Volume and Issue: 169, P. 214161 - 214161

Published: Dec. 23, 2024

Language: Английский

Citations

0
Cuproptosis: an emerging domain for copper-based nanomaterials mediated cancer therapy DOI
Fan Zhao,

Zhuangzhuang Zhao,

Hao Gao

et al.

MedMat., Journal Year: 2024, Volume and Issue: 1(2), P. 74 - 94

Published: Dec. 1, 2024

Cuproptosis, a newly discovered copper-dependent mode of cell death, has received extensive attention in the field cancer therapy due to its specific activation pathway. Rapid accumulation large amounts copper ions within cells achieve overload is key activating cuproptosis. Advanced nanotechnology offers considerable promise for delivering cells, which copper-based nanomaterials have been proposed evoke cuproptosis-mediated therapy. However, it still great challenge induce specifically tumors and efficiently activate subsequent cuproptosis-related molecular pathways. Therefore, necessary summarize strategies used effectively or amplify cuproptosis based on currently developed nanomaterials, providing ideas design future. In this review, that can be are systematically classified selection. Subsequently, sensitization using provided therapeutic efficiency. Meanwhile, combination therapies maximizing treatment efficacy delineated. Ultimately, remaining challenges feasible future directions use tumor also discussed.

Language: Английский

Citations

0