Matéria (Rio de Janeiro),
Journal Year:
2024,
Volume and Issue:
29(4)
Published: Jan. 1, 2024
ABSTRACT
The
increase
in
hospital-acquired
infections
(HAIs)
associated
with
medical
devices
underscores
the
need
for
antimicrobial
coatings.
This
study
aims
to
compare
efficacy,
biocompatibility,
ion
release,
and
durability
of
silver
nanoparticles,
copper
coatings,
zinc
oxide
nanostructures
as
coatings
devices.
Coatings
were
prepared
characterized,
efficacy
tested
against
E.
coli
S.
aureus
via
inhibition
zone
measurements.
Silver
demonstrated
highest
effect,
zones
averaging
90%,
while
showed
moderate
80%
70%,
respectively.
Biocompatibility,
assessed
using
human
fibroblasts
an
MTT
assay,
cell
viability
oxide,
followed
by
silver.
Durability
tests
under
simulated
physiological
conditions
indicated
that
retained
over
90%
structural
integrity,
greater
degradation.
Ion
release
profiles
highlighted
silver’s
rapid
ideal
short-term
activity,
steady,
sustained
release.
These
findings
suggest
immediate
infection
control,
offer
balanced
long-term
safety
durability,
making
them
suitable
extended
applications
Chemical Engineering Journal,
Journal Year:
2024,
Volume and Issue:
496, P. 154223 - 154223
Published: July 22, 2024
The
increasing
prevalence
of
antibiotic-resistant
illnesses
worldwide
calls
for
the
development
novel
antibacterial
strategies,
including
ones
based
on
antibacterials
materials.
This
work
reports
combined
effects
piezoelectric
poly(vinylidene
fluoride-co-trifluoroethylene)
(P(VDF-TrFE))
and
propolis,
a
natural
antimicrobial
agent,
various
material
structures
(2D
films
3D
structures)
to
increase
surface
contact
area.
It
is
shown
that
addition
propolis
has
substantial
impact
texture
mechanical
properties
In
particular,
exhibit
improved
distribution
enhanced
stability
in
comparison
2D
films.
experiments
conducted
Escherichia
coli
(E.
coli)
Staphylococcus
aureus
(S.
aureus)
demonstrate
significant
reduction
bacteria,
particular
when
larger
concentrations
are
applied
stimulation
used
at
specified
frequencies,
taking
therefore
advantage
charge
variation
associated
response.
particularly
effect
resistant
S.aureus
emphasising
huge
potential
this
hybrid
biomedical
applications.
Thus,
it
demonstrated
polymers
combination
with
agents,
represents
suitable
approach
address
microbial
resistance,
important
applications
areas
wound
dressings,
implant
coatings,
high
traffic
surfaces,
among
others.
