Blazing Carbon Dots: Unfolding its Luminescence Mechanism to Photoinduced Biomedical Applications DOI

Nirmiti Mate,

Vinita Satwani,

Pranav Tiwari

et al.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

Abstract Carbon dots (CDs) are carbon‐based nanomaterials that have garnered immense attention owing to their exceptional photophysical and optoelectronic properties. They been employed extensively for biomedical imaging phototherapy due superb water dispersibility, low toxicity, outstanding biocompatibility, tissue permeability. This review summarizes the structural classification of CDs, CDs according precursor sources, luminescence mechanism CDs. The modification in via various doping routes is comprehensively reviewed, effect such alterations on properties, as absorbance, photoluminescence (PL), reactive oxygen species generation ability, also highlighted. strives summarize role cellular fluorescence lifetime metabolism. Subsequently, recent advancements future potential nanotheranostic agents discussed. Herein, we discussed photothermal, photodynamic, synergistic therapy anticancer, antiviral, antibacterial applications. overall summary highlights prospects CD‐based research bioimaging biomedicine.

Language: Английский

Rapid and Large-Scale Synthesis of Chiral and Fluorescent Sulfur Quantum Dots for Intracellular Temperature Monitoring DOI Creative Commons
Li Zhao,

Tianjian Sha,

Yufu Liu

et al.

Chemical & Biomedical Imaging, Journal Year: 2024, Volume and Issue: 2(12), P. 817 - 824

Published: Sept. 20, 2024

The large-scale preparation of fluorescent nanomaterials with laboratory-relevant chemical and optical properties will greatly forward their consumer market applications; however, it still remains challenging. In this work, a universal strategy was developed for the rapid synthesis sulfur quantum dots that recently has drawn great attention because unique characteristics. From fact empty 3d orbitals sulfide species are able to bind lone-pair π electrons heteroatomic groups, many amino-group containing compounds, such as amino acid polyethylenimine molecules, were exploited synthesize dots. This 10 min period endowed bright blue fluorescence also chirality. Due user-friendly operation, can be extended yield 16.844 g one batch experiment. Moreover, found exhibited reversible temperature-dependent luminescent property sensitivity 0.72%/°C, which showed excellent intracellular temperature monitoring capability inflammation-related disease diagnostics.

Language: Английский

Citations

2

Recent Advances in Carbon Dots: Applications in Oral Diseases DOI
Jing Wang, Yifan Zhao,

Lingxiang Sun

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 19, 2024

Over the years, oral and maxillofacial injuries, mainly caries, pulpitis, bone defects, cancer, often involve a variety of organs tissues, resulting in structural dysfunction, adverse effects on facial appearance, not only affecting people's chewing, swallowing other physiological functions, but also to physical mental health burden. As type carbon-based nanomaterial, carbon dots (CDs) have been widely used diagnosis treatment diseases due its excellent optical properties, good biocompatibility low toxicity. In addition, surface functionalization or passivation CDs can change properties CDs, such as water solubility chemiluminescence, broaden biomedical potential CDs. this review, latest research progress modified hard tissue regeneration, tumor treatment, antibacterial activity, dentin pulp complex teeth whitening, wound healing, drug release, fluorescence tracer bioimaging were reviewed. we discussed problems future direction development.

Language: Английский

Citations

2

Progress on Carbon Dots with Intrinsic Bioactivities for Multimodal Theranostics DOI Open Access
Hao Zhang, Hao Liu, Xiaohui Liu

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 23, 2024

Abstract Carbon dots (CDs) with intrinsic bioactivities are candidates for bioimaging and disease therapy due to their diverse bioactivities, high biocompatibility, multiple functionalities in multimodal theranostics. It is a multidisciplinary research hotspot that includes biology, physics, materials science, chemistry. This progress report discusses the CDs applications The relationship between synthesis structure of summarized analyzed from material chemical perspective. including anti‐tumor, antibacterial, anti‐inflammatory etc. discussed biological points view. Subsequently, optical electronic properties can be applied biomedical field physical Based on functional review CDs, reviewed, diagnosis treatment, activity, Unlike previous reviews, this combines disciplines gain more comprehensive understanding mechanisms, functions, bioactivities.

Language: Английский

Citations

1

Multifunctional Ag2S/g-C3N4 Nanoparticles for Photodynamic and Photothermal Cancer Therapy under Near-Infrared Excitation DOI
Hongliang Wang,

Jiarui You,

Dongmei Shi

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(17), P. 19904 - 19914

Published: Aug. 27, 2024

Photothermal therapy (PTT) agents possess the capability to absorb light and transform it into heat, providing a promising approach for inhibiting eradicating tumor cells. Therefore, there is significant interest in developing novel PTT with superior biocompatibility photothermal conversion efficiency. Herein, Ag2S/g-C3N4 nanoparticles (NPs) exceptional near-infrared absorption performance were successfully synthesized using hydrothermal method. The efficiency of NPs reached 31.28% under 808 nm laser irradiation, surpassing that most reported agents. simultaneous application an resulted augmentation reactive oxygen species (ROS) generation, including ·O2– ·OH, which, turn, triggered apoptosis death cells via photodynamic (PDT). efficacy elimination was confirmed through cellular animal experiments, demonstrating synergistic effectiveness PDT. Importantly, no regrowth observed 30 days after treatment. These results highlight potential combining therapies nanomaterials effective therapy, offering catalytic-photothermal utilizing nanomaterials.

Language: Английский

Citations

0

Blazing Carbon Dots: Unfolding its Luminescence Mechanism to Photoinduced Biomedical Applications DOI

Nirmiti Mate,

Vinita Satwani,

Pranav Tiwari

et al.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

Abstract Carbon dots (CDs) are carbon‐based nanomaterials that have garnered immense attention owing to their exceptional photophysical and optoelectronic properties. They been employed extensively for biomedical imaging phototherapy due superb water dispersibility, low toxicity, outstanding biocompatibility, tissue permeability. This review summarizes the structural classification of CDs, CDs according precursor sources, luminescence mechanism CDs. The modification in via various doping routes is comprehensively reviewed, effect such alterations on properties, as absorbance, photoluminescence (PL), reactive oxygen species generation ability, also highlighted. strives summarize role cellular fluorescence lifetime metabolism. Subsequently, recent advancements future potential nanotheranostic agents discussed. Herein, we discussed photothermal, photodynamic, synergistic therapy anticancer, antiviral, antibacterial applications. overall summary highlights prospects CD‐based research bioimaging biomedicine.

Language: Английский

Citations

0