New Journal of Chemistry, Journal Year: 2024, Volume and Issue: 48(36), P. 15948 - 15955
Published: Jan. 1, 2024
Glucose oxidase has great potential as a bio-catalyst for the determination of glucose and H 2 O concentration, but it is sensitive to environmental influences poor recoverability.
Language: Английский
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 497, P. 154517 - 154517
Published: Aug. 3, 2024
Language: Английский
Citations
15
Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 19, 2024
Abstract The combination of photothermal and chemodynamic therapy (PTT‐CDT) using single‐atom nanozymes (SAzymes) shows great promise in combating pathogenic drug‐resistant bacteria. However, the conversion efficiency catalytic activity SAzymes with solely metal sites remain inadequate, often requiring high doses for effectiveness. Herein, a bimetallic single‐atomic Fe Cu active (FeCu BSNs) designed is reported efficient treatment bacterial infections through hyperthermia‐amplified nanozyme catalysis strategy. FeCu BSNs demonstrate remarkable peroxidase (POD) specific (SA) 752.25 U mg −1 , which 2.3 folds larger than that (323.45 ). Additionally, their effect achieve up to 56.26%, two times higher (29.69%) (25.55%). These enhancements can be attributed hybridization sites. BSNs‐mediated PTT‐CDT demonstrates potent antibacterial effects both vitro vivo models, levels reactive oxygen species (ROS) generation hyperthermia. This study effectively validates application ultralow‐dose wound healing, offering promising approach enhanced recovery.
Language: Английский
Citations
6
Nano Letters, Journal Year: 2024, Volume and Issue: 24(45), P. 14337 - 14345
Published: Oct. 29, 2024
Nanomaterials with peroxidase-like activity and photothermal conversion efficiency have garnered significant attention for their ability to generate cytotoxic hydroxyl radicals provide synergistic therapeutic effects. Selecting nanozymes suitable properties carriers is crucial maximizing efficacy. While the mucin family known its mucoadhesive, glycosylated structures that enhance drug bioavailability targeting, potential in remains underexplored. Here, we utilize mucin-2 facilitate osmium nanoclusters (Os@Mucin), creating protein-corona-like nanozymes. This configuration bestows Os@Mucin excellent (769 U/mg) (22.83%, 808 nm). Mucin-2 promotes Os uptake by cells, allowing exhibit tumor environment-responsive activity, further enhanced under conditions targeted cytotoxicity
Language: Английский
Citations
4
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140814 - 140814
Published: Feb. 1, 2025
Language: Английский
Citations
0
Journal of Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 689, P. 137247 - 137247
Published: March 4, 2025
Language: Английский
Citations
0
Journal of Colloid and Interface Science, Journal Year: 2025, Volume and Issue: unknown, P. 137401 - 137401
Published: March 1, 2025
Language: Английский
Citations
0
Microorganisms, Journal Year: 2025, Volume and Issue: 13(4), P. 708 - 708
Published: March 21, 2025
The rise of multi-drug-resistant (MDR) bacteria poses a severe global threat to public health, necessitating the development innovative therapeutic strategies overcome these challenges. Copper-based nanomaterials have emerged as promising agents due their intrinsic antibacterial properties, cost-effectiveness, and adaptability for multifunctional approaches. These materials exhibit exceptional potential in advanced therapies, including chemodynamic therapy (CDT), photothermal (PTT), photodynamic (PDT). Their unique physicochemical such controlled ion release, reactive oxygen species (ROS) generation, tunable catalytic activity, enable them target MDR effectively while minimizing off-target effects. This paper systematically reviews mechanisms through which Cu-based enhance efficiency emphasizes specific performance field. Key factors influencing properties—such electronic interactions, characteristics, size effects, ligand single-atom doping, geometric configurations—are analyzed depth. By uncovering copper-based nanomaterials, this work aims inspire approaches that improve patient outcomes, reduce burden bacterial infections, health initiatives.
Language: Английский
Citations
0
Journal of Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 693, P. 137615 - 137615
Published: April 16, 2025
Language: Английский
Citations
0
Materials Today Bio, Journal Year: 2025, Volume and Issue: unknown, P. 101830 - 101830
Published: May 1, 2025
Language: Английский
Citations
0
Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(32)
Published: Oct. 14, 2024
Abstract Chronic wounds are characterized by long‐term inflammation, including diabetic ulcers, traumatic etc., which provide an optimal environment for bacterial proliferation. At present, antibiotics the main clinical treatment method chronic wound infections. However, overuse of may accelerate emergence drug‐resistant bacteria, poses a significant threat to human health. Therefore, there is urgent need develop new therapeutic strategies Nanozyme‐based antimicrobial therapy (NABT) emerging strategy with broad‐spectrum activity and low drug resistance compared traditional antibiotics. NABT has shown great potential as catalyzing generation reactive oxygen species (ROS) its enzyme‐like catalytic properties, producing powerful bactericidal effect without developing resistance. cascade technology offers approach infection control, effectively improving efficacy activating cascades against cell membranes intracellular DNA while minimizing side effects. it worth noting that this still in early stages research. This article comprehensively reviews classification, current methods infection, different types nanozymes, application nanozyme reaction therapy, future challenges prospects.
Language: Английский
Citations
2