Enhancing Regeneration and Functionality of Excitable Tissues via Integrating Bioelectronics and Bioengineered Constructs DOI Creative Commons

Zijie Meng,

Bingsong Gu,

Cong Yao

et al.

International Journal of Extreme Manufacturing, Journal Year: 2024, Volume and Issue: 7(2), P. 022004 - 022004

Published: Nov. 15, 2024

Abstract The inherent complexities of excitable cardiac, nervous, and skeletal muscle tissues pose great challenges in constructing artificial counterparts that closely resemble their natural bioelectrical, structural, mechanical properties. Recent advances have increasingly revealed the beneficial impact bioelectrical microenvironments on cellular behaviors, tissue regeneration, therapeutic efficacy for tissues. This review aims to unveil mechanisms by which electrical enhance regeneration functionality cells tissues, considering both endogenous cues from electroactive biomaterials exogenous stimuli external electronic systems. We explore synergistic effects these microenvironments, combined with structural guidance, using engineering scaffolds. Additionally, emergence micro/nanoscale bioelectronics has significantly broadened this field, facilitating intimate interactions between implantable across cellular, tissue, organ levels. These enable precise data acquisition localized modulation cell functionalities through intricately designed components according physiological needs. integration promises optimal outcomes, highlighting a growing trend developing living construct-bioelectronic hybrids restoring monitoring damaged Furthermore, we envision critical next-generation hybrids, focusing integrated fabrication strategies, development ionic conductive biomaterials, convergence biosensors.

Language: Английский

A biodegradable piezoelectric scaffold promotes spinal cord injury nerve regeneration DOI

Jinjing Zhang,

Qiong Wang, Xiaoyi Tang

et al.

Nano Energy, Journal Year: 2024, Volume and Issue: unknown, P. 110382 - 110382

Published: Oct. 1, 2024

Language: Английский

Citations

4
Multifunctional magneto-electric and exosome-loaded hydrogel enhances neuronal differentiation and immunoregulation through remote non-invasive electrical stimulation for neurological recovery after spinal cord injury DOI
Wubo Liu, Qiang Liu, Zeqin Li

et al.

Bioactive Materials, Journal Year: 2025, Volume and Issue: 48, P. 510 - 528

Published: Feb. 28, 2025

Language: Английский

Citations

0
Emerging Piezoelectric Metamaterials for Biomedical Applications DOI Creative Commons

Zishuo Yan,

Huy Quang Tran, Dongxin Ma

et al.

Published: Nov. 21, 2024

Emerging piezoelectric metamaterials hold immense promise for biomedical applications by merging the intrinsic electrical properties of piezoelectricity with precise architecture metamaterials. This review provides a comprehensive overview various materials- such as molecular crystals, ceramics, and polymers-known their exceptional performance biocompatibility. We explore advanced engineering approaches, including design, supramolecular packing, 3D assembly, which enable customization targeted applications. Particular attention is given to pivotal role metamaterial structuring in development 0D spheres, 1D fibers tubes, 2D films, scaffolds. Key applications, tissue engineering, drug delivery, wound healing, biosensing, are discussed through illustrative examples. Finally, article addresses critical challenges future directions, aiming drive further innovations biomaterials next-generation healthcare technologies.

Language: Английский

Citations

3
Cost-efficient breakthrough: Fabricating multifunctional woven hydrogels from water-soluble polyvinyl alcohol yarn DOI

Chenxing Xiang,

Yuanhao Tian,

Huiming Ning

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 500, P. 157292 - 157292

Published: Nov. 1, 2024

Language: Английский

Citations

1
Enhancing Regeneration and Functionality of Excitable Tissues via Integrating Bioelectronics and Bioengineered Constructs DOI Creative Commons

Zijie Meng,

Bingsong Gu,

Cong Yao

et al.

International Journal of Extreme Manufacturing, Journal Year: 2024, Volume and Issue: 7(2), P. 022004 - 022004

Published: Nov. 15, 2024

Abstract The inherent complexities of excitable cardiac, nervous, and skeletal muscle tissues pose great challenges in constructing artificial counterparts that closely resemble their natural bioelectrical, structural, mechanical properties. Recent advances have increasingly revealed the beneficial impact bioelectrical microenvironments on cellular behaviors, tissue regeneration, therapeutic efficacy for tissues. This review aims to unveil mechanisms by which electrical enhance regeneration functionality cells tissues, considering both endogenous cues from electroactive biomaterials exogenous stimuli external electronic systems. We explore synergistic effects these microenvironments, combined with structural guidance, using engineering scaffolds. Additionally, emergence micro/nanoscale bioelectronics has significantly broadened this field, facilitating intimate interactions between implantable across cellular, tissue, organ levels. These enable precise data acquisition localized modulation cell functionalities through intricately designed components according physiological needs. integration promises optimal outcomes, highlighting a growing trend developing living construct-bioelectronic hybrids restoring monitoring damaged Furthermore, we envision critical next-generation hybrids, focusing integrated fabrication strategies, development ionic conductive biomaterials, convergence biosensors.

Language: Английский

Citations

0