A novel nanomedicine integrating ferroptosis and photothermal therapy, well-suitable for PD-L1-mediated immune checkpoint blockade DOI Creative Commons
Yujun Bao, Guanghao Li,

Siqi Li

et al.

Materials Today Bio, Journal Year: 2024, Volume and Issue: 29, P. 101346 - 101346

Published: Nov. 16, 2024

Language: Английский

A cuproptosis-based nanomedicine suppresses triple negative breast cancers by regulating tumor microenvironment and eliminating cancer stem cells DOI
Chen Xiao, Xing Wang, Shiyou Li

et al.

Biomaterials, Journal Year: 2024, Volume and Issue: 313, P. 122763 - 122763

Published: Aug. 17, 2024

Language: Английский

Citations

21
A novel silkworm excrement-derived nanomedicine integrating ferroptosis and photodynamic therapy, well-suitable for PD-L1-mediated immune checkpoint blockade DOI
Yujun Bao, Guanghao Li, Mingyang Liu

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 505, P. 159676 - 159676

Published: Jan. 17, 2025

Language: Английский

Citations

2
A proton pump inhibitor-programmed ROS generator enhances the synergistic efficacy of chemo-/chemodynamic therapy with reduced renal injury DOI
Jiaxuan Li, Yanqing Li, Yi Wang

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159201 - 159201

Published: Jan. 1, 2025

Language: Английский

Citations

1
Drug Delivery Systems Based on Metal–Organic Frameworks for Tumor Immunotherapy DOI Creative Commons
Ning Yang,

Zongyan He,

Tianqun Lang

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(2), P. 225 - 225

Published: Feb. 10, 2025

Metal–organic frameworks (MOFs) are a class of inorganic-organic hybrid nanoparticles formed by the coordination metal ions/clusters and organic ligands. Due to their high porosities, large surface areas, adjustable structures, responsiveness light/sound, etc., MOFs have shown great clinical potential in field tumor therapy. Tumor immunotherapy exerts antitumor effects through reshaping immune microenvironment, showing significant preclinical advantages. Based on mechanisms immunity activation, agents can be divided into chemotherapeutic agents, immunomodulators, enzymes, vaccines oligonucleotide drugs, etc. Herein, we review MOFs-based drug delivery systems for immunotherapy. The classification MOFs, followed activation mechanisms, first introduced. Drug based with different also summarized, especially synergetic triggered loadings. Furthermore, merits drawbacks strategies promote applications discussed.

Language: Английский

Citations

1
HIFU postoperative hypoxia enables metal-organic frameworks amplifying banoxantrone and STING activation for enhanced immunotherapy DOI
Ying‐Lin Zhou,

Xinchang Huang,

Dezhou Wu

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159704 - 159704

Published: Jan. 1, 2025

Language: Английский

Citations

0
Advanced Strategies of Covalent Organic Framework Nanomedicines in Targeting and Overcoming Biological Barriers DOI Creative Commons
Lei Zhong, Jinpeng Liu,

Yingming Xiao

et al.

Asian Journal of Pharmaceutical Sciences, Journal Year: 2025, Volume and Issue: unknown, P. 101066 - 101066

Published: May 1, 2025

Language: Английский

Citations

0
A novel nanomedicine integrating ferroptosis and photothermal therapy, well-suitable for PD-L1-mediated immune checkpoint blockade DOI Creative Commons
Yujun Bao, Guanghao Li,

Siqi Li

et al.

Materials Today Bio, Journal Year: 2024, Volume and Issue: 29, P. 101346 - 101346

Published: Nov. 16, 2024

Language: Английский

Citations

1