Food Chemistry X, Journal Year: 2024, Volume and Issue: 25, P. 102093 - 102093
Published: Dec. 12, 2024
Total antioxidant capacity (TAC) is an important indicator for assessing the merit of natural plants and foods. Herein, a visual TAC assay developed based on oxidase-like activity nitrogen-doped carbon nanotubes loaded with Fe nanoparticles (FeNPs@NCNT), which prepared via high-temperature pyrolysis metal-organic framework precursors can catalyze oxidation colorless
Language: Английский
ACS Applied Nano Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 11, 2025
Constructing nanozyme-based single atoms with exposed metal-Nx catalytic sites for alendronate sodium (ALDS) tablet quality control is a complex and uncommon task. Herein, we presented an innovative colorimetric assay to detect ALDS utilizing carbon-supported Fe/Co dual-atom nanozymes (Fe/CoSA-NCs) derived from precursor of porphyrin covalent organic frameworks (COFs). The Fe/CoSA-NC nanozymes, featuring Fe–N5 active site electronic interactions between Fe Co, exhibited enhanced peroxidase-like activity. Experimental findings theoretical calculations elucidated that the superior activity Fe/CoSA-NCs stemmed synergistic effect dual atoms, which boosted substrate adsorption reduced reaction barrier. When integrated Fe/CoSA-NCs, could be inhibited due ALDS-Fe3+ coordination. Leveraging this mechanism, rapid selective method was developed detecting ALDS. sensor showed detection limit 0.96 μM in phosphate buffer, surpassing traditional techniques terms efficiency, accuracy, simplicity. Moreover, system successfully utilized pharmaceutical determine urine samples. This work opens powerful avenue developing efficient COFs expands potential applications nanozyme clinical pharmacy.
Language: Английский
Citations
1
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159936 - 159936
Published: Jan. 1, 2025
Language: Английский
Citations
0
Small, Journal Year: 2025, Volume and Issue: unknown
Published: March 14, 2025
Abstract High catalytic efficiency is persistently pursued to generate high‐performance nanozymes. Metal elements are active centers where metal–organic frameworks (MOFs) play a role. In this work, library of MOFs‐derived nanozyme constructed based on metal salts and 1 H ‐1,2,3‐triazole (MET). Triazole has three N atoms; the intrinsic high content beneficial improve affinity substrate 2 O . Meanwhile, different kinds metals can be introduced by changing salts, through which bimetallic or trimetallic MOFs constructed. Amongst various single–, bi‐, MET nanozymes, MET‐Fe Zn 0.5 exhibits best peroxidase (POD)‐like activity. The results demonstrate that introduction accelerates electron transfer promotes conversion Fe 3+ 2+ in nanozyme, thus enhancing POD‐like activity nanozyme. particular, excellent antibacterial efficiency. A study mechanism indicates good adhesion bacterial membrane work conjunction with reactive oxygen species, disrupting oxidative phosphorylation, DNA replication, biosynthesis essential amino acids cofactors within bacteria, leading damage and, eventually death bacteria. These suggest N‐coordination number great potential as new‐generation
Language: Английский
Citations
0
Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
This work introduces a novel bimetallic MOF with superior endotoxin detection and enhanced catalytic activity for broader diagnostic applications.
Language: Английский
Citations
1
Food Chemistry X, Journal Year: 2024, Volume and Issue: 25, P. 102093 - 102093
Published: Dec. 12, 2024
Total antioxidant capacity (TAC) is an important indicator for assessing the merit of natural plants and foods. Herein, a visual TAC assay developed based on oxidase-like activity nitrogen-doped carbon nanotubes loaded with Fe nanoparticles (FeNPs@NCNT), which prepared via high-temperature pyrolysis metal-organic framework precursors can catalyze oxidation colorless
Language: Английский
Citations
0