Breakthrough in Cancer Therapy: Lutetium Texaphyrin-Celecoxib Conjugate for Immune and Photodynamic Treatment DOI Creative Commons
Qihang Ding, Yue Wang, Pengfei Zhang

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Kim et al . present a small-molecule photosensitizer, LuCXB, which combines COX-2 inhibitor (celecoxib) with near-infrared lutetium texaphyrin photocatalyst and was loaded CD133-aptamer functionalized exosome for cancer stem cells targeting.

Language: Английский

Complexity made easy: Aggregation‐induced emission small molecules for cancer diagnosis and phototherapies DOI Creative Commons

Luojia Chen,

Si‐Ling Chen,

Yuncong Yuan

et al.

Aggregate, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 2, 2024

Abstract Phototheranostics has garnered sustained attention due to its significant potential for revolutionizing conventional cancer treatment strategies. While being one of the most commonly employed strategies constructing phototheranostic systems by engineering integration photosensitizers (PSs) into nanosystems, nano‐PSs face challenges including complexity in preparation process, low delivery efficiency, and toxicity issues. Contrastingly, burgeoning popularity small molecule PSs characterized aggregation‐induced emission (AIE) become evident arena phototheranostics. This preference is underscored their well‐defined structures, adjustable photophysical properties, toxicity. Therefore, acquiring profound insights pioneering strides achievable through a solitary PS with AIE tumor phototheranostics paramount scientific significance. In this review, we will discuss recent progress properties diagnosis phototherapies representative examples, guided ethos “Complexity made easy”. We also look forward future development direction molecules, central objective advancing research focal emphasis on simplicity, expeditiousness, safety.

Language: Английский

Citations

10
Self-Propelling Intelligent Nanomotor: A Dual-Action Photothermal and Starvation Strategy for Targeted Deep Tumor Destruction DOI
Ling Mei, Qihang Ding,

Yuxin Xie

et al.

Biomaterials, Journal Year: 2024, Volume and Issue: 315, P. 122968 - 122968

Published: Nov. 15, 2024

Language: Английский

Citations

7
Illuminating oral health: AIEgens for phototheranostics DOI Creative Commons
Jingyuan Chen, Wenhao Yan, Xinyu Wang

et al.

Published: March 1, 2025

Language: Английский

Citations

0
Breakthrough in Cancer Therapy: Lutetium Texaphyrin-Celecoxib Conjugate for Immune and Photodynamic Treatment DOI Creative Commons
Qihang Ding, Yue Wang, Pengfei Zhang

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Kim et al . present a small-molecule photosensitizer, LuCXB, which combines COX-2 inhibitor (celecoxib) with near-infrared lutetium texaphyrin photocatalyst and was loaded CD133-aptamer functionalized exosome for cancer stem cells targeting.

Language: Английский

Citations

0