ACS Omega,
Journal Year:
2024,
Volume and Issue:
10(1), P. 1610 - 1623
Published: Dec. 27, 2024
Nickel-based
metal–organic
frameworks,
denoted
as
three-dimensional
nickel
trimesic
acid
frameworks
(3D
Ni-TMAF),
are
gaining
significant
attention
for
their
application
in
nonenzymatic
glucose
sensing
due
to
unique
properties.
Ni-MOFs
possess
a
high
surface
area,
tunable
pore
structures,
and
excellent
electrochemical
activity,
which
makes
them
ideal
facilitating
electron
transfer
enhancing
the
catalytic
oxidation
of
glucose.
This
research
describes
new
enzyme-mimic
biosensor
biological
solutions
that
utilizes
3D
nanospheres
Ni-TMAF
created
layer-by-layer
on
highly
porous
substrate.
The
based
represent
promising
approach,
leveraging
properties
provide
efficient,
stable,
potentially
more
cost-effective
alternatives
traditional
sensors.
MOF
is
synthesized
from
(TMA)
nitrate
hexahydrate
through
solvothermal
reaction
process.
resulting
crystalline
structure
with
large
area
numerous
active
sites
toward
indeed
known
electrocatalytic
particularly
context
under
alkaline
conditions.
centers
facilitate
efficient
redox
reactions,
leading
sensitivity
203.89
μA
μM–1
cm–2
lower
LOD
0.33
μM
fast
response
time
<3
s
Their
stability,
cost-effectiveness,
performance
make
material
Advanced Sustainable Systems,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 7, 2025
Abstract
Inorganic
nanozyme‐based
biosensors
are
extensively
used
for
detecting
toxic
molecules,
offering
an
alternative
to
fragile
enzyme‐based
sensors
and
conventional
analytic
tools.
However,
inorganic
materials
can
pose
environmental
risks
due
toxicity
low
sustainability
properties,
which
may
lead
pollution
after
intended
use.
To
address
these
limitations,
sustainable
organic
sensing
platforms
essential
overcoming
issues
effectively
agrichemicals.
In
this
study,
a
second‐generation,
compound‐based
nanozyme
(EU
nanozyme)
is
introduced,
exhibits
peroxidase‐like
catalytic
activity.
The
synthesized
using
modified,
self‐assembled
fabrication
procedure
that
produced
homogenous,
spherical
within
2
h
incorporated
partially
mimicked
cofactor
of
the
natural
peroxidase.
This
EU
decent
kinetic
profiles
(
Km
=
0.006
m
,
H
O
),
along
with
degradability
biocompatibility,
making
it
suitable
direct
implementation
in
agricultural
environments
highlighting
its
sustainability.
colorimetric
platform
detects
herbicides
(e.g.,
Atrazine),
sensitivity
Limit
Detection
(LOD)
0.231
pg
mL
−1
strong
selectivity
among
more
than
six
relative
agrichemicals/and
other
pesticides,
specificity
corn
samples
LOD
0.394
µgmL
short
detection
time
up
3
min.
It
envisioned
offer
promising
advancements
enhancing
safety.
Advanced Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 7, 2025
Abstract
High‐entropy
alloys
(HEAs)
have
garnered
extensive
attention
owing
to
their
broad
compositional
tunability
and
high
catalytic
activity.
However,
precisely
modulating
the
enzyme‐like
activity
of
HEAs
enhancing
biocompatibility
for
biological
applications
remain
severely
challenging.
Herein,
PtRuFeCoNi
HEA
nanowires
(NWs)
are
synthesized
by
adjusting
metal
composition
surface‐engineered
with
polydopamine
(PDA)
form
NWs@PDA
nanozymes
(HEzymes@PDA)
superior
photothermal
properties.
Density
functional
theory
calculations
Sabatier
principle
reveal
that
self‐polymerized
PDA
surface
engineering
moderately
lowers
d‐band
center
HEAs,
optimizes
charge
distribution,
enhances
adsorption–desorption
efficiency
substrates.
As
a
proof‐of‐concept,
HEzymes@PDA
synergistically
integrated
hydrogels
biosensing
analysis.
This
study
presents
an
innovative
paradigm
designing
highly
active
via
demonstrates
immense
potential
in
sensing
applications.
