Development and antibacterial evaluation of a dopamine-modified curcumin@zinc-based organic framework DOI

Jiayi Qin,

Haiyan Zhang, Xianying Cao

et al.

Dalton Transactions, Journal Year: 2024, Volume and Issue: 54(3), P. 1256 - 1260

Published: Nov. 30, 2024

The elimination of S. aureus was achieved through the synergy chemo, photothermal therapy (PPT), and Zn 2+ .

Language: Английский

Antimicrobial carbon materials-based quantum dots: From synthesis strategies to antibacterial properties for diagnostic and therapeutic applications in wound healing DOI
Iman Zare,

Shima Zahed Nasab,

Amid Rahi

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 522, P. 216211 - 216211

Published: Sept. 18, 2024

Language: Английский

Citations

9
Preparation, Coating, and Multimodal Therapeutic Properties of an Anticancer System Based on UiO-66(Ce) DOI
Quan Hu, Chen Lei, Yue Sun

et al.

Inorganic Chemistry, Journal Year: 2025, Volume and Issue: 64(6), P. 2809 - 2814

Published: Jan. 31, 2025

UiO-66(Ce) was prepared from cerium metal, which could trigger Fenton-like reactions. A system DOX@UiO-66(Ce)@TA-Fe constructed by coating a metal polyphenol layer (TA-Fe) on the surface of DOX@UiO-66(Ce), loaded with anticancer drug doxorubicin hydrochloride (DOX). It produce reactive oxygen species to realize chemodynamic therapy and show stimuli-responsive release behaviors chemotherapy. In addition, displayed biocompatibility normal cells (L929 cells) toxicity cancer (MCF-7 cells), implying an ideal effect for multimodal therapy.

Language: Английский

Citations

0
A Multifunctional Fe‐Based Metal–Organic Framework With Ferroptosis for Synergistic Therapy DOI
Lu Hong, Qiaoyu Chen,

Lei Rao

et al.

Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(5)

Published: April 8, 2025

ABSTRACT Generally, single cancer treatment is insufficient to achieve ideal therapeutic effect. Multimodal therapy has the potential overcome efficacy challenges and reveals great promise in enhancing Herein, a combination system (DOX@Fe‐PBC) based on chemotherapy, chemodynamic (CDT), ferroptosis was constructed by loading anticancer drug doxorubicin hydrochloride (DOX) into Fe‐based metal–organic framework (Fe‐PBC). In simulated tumor microenvironment, released DOX be DNA intercalator topoisomerase II inhibitor realize chemotherapy (CT) iron ions were delivered induce Fenton reaction, which boost generation of •OH, resulting enhancement effect (CDT). Meantime, could consume glutathione (GSH) reduce expression peroxidase 4 (GPX4); then, lipid peroxides (LPO) accumulated ferroptosis. DOX@Fe‐PBC provided an effective strategy CDT, treatment.

Language: Английский

Citations

0
Enhanced Intracellular IR780 Delivery by Acidity-Triggered PEG-Detachable Hybrid Nanoparticles to Augment Photodynamic and Photothermal Combination Therapy for Melanoma Treatment DOI Creative Commons

Min‐Chen Tsai,

L. T. Hsiao,

Yen-Hsuan Chang

et al.

ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown

Published: April 12, 2025

The PEGylation of drug-carrying nanoparticles has often been used to prolong blood circulation and improve drug deposition at tumor sites. Nevertheless, the PEG-rich hydrophilic surfaces retard release payloads internalization therapeutic by cancer cells, thus lowering anticancer efficacy. To boost potency combined photodynamic therapy (PDT) photothermal (PTT) against melanoma conquering PEG dilemma, herein, hybrid PEGylated chitosan-covered polydopamine (PDA) (PCPNs) with acidity-elicited detachment ability were fabricated as carriers IR780, a small-molecule photosensitizer for PTT PDT. IR780@PCPNs displayed uniform, solid-like spherical shape sound colloidal stability. Under near-infrared (NIR) irradiation, showed prominent conversion efficiency (ca. 54.6%), robust stability, reduced IR780 photobleaching, sufficient singlet oxygen (1O2) production, glutathione-depleting ability. Moreover, environmental pH being from 7.4 5.0 37 °C, decreased interactions between PCPNs due increased protonation phenolic hydroxyl residues within PDA primary amine groups chitosan accelerated species IR780@PCPNs. Importantly, cellular uptake B16F10 was remarkably promoted in weakly acidic milieu upon driven disintegration acid-labile benzoic imine. With NIR internalized generated hyperthermia 1O2 damage mitochondria, thereby effectively inhibiting proliferation cells. Collectively, our findings present practical strategy amplifying efficacy PDT using PEG-detachable

Language: Английский

Citations

0
Visible light-powered photodynamic antibacterial chlorophyllin-derived metallochlorins DOI

Yuling Xue,

Kuoran Xing,

Max Jing Rui Tham

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 504, P. 158345 - 158345

Published: Dec. 21, 2024

Language: Английский

Citations

2
Prussian blue-EGCG nanoparticles for synergistic photothermal and chemo anticancer therapy in vitro DOI
Bingquan Chen,

Manni Wu,

Jiayi Qin

et al.

Dyes and Pigments, Journal Year: 2024, Volume and Issue: unknown, P. 112487 - 112487

Published: Oct. 1, 2024

Language: Английский

Citations

1
Preparation of Stable and Biocompatible MOF@SiO2 Nanoparticles for Oxybutynin Loading and Pelvic Floor Muscle Repair DOI
Aihong Li, Jie Zhang, Lijun Feng

et al.

Journal of the Indian Chemical Society, Journal Year: 2024, Volume and Issue: 101(10), P. 101348 - 101348

Published: Aug. 30, 2024

Language: Английский

Citations

0
Development and antibacterial evaluation of a dopamine-modified curcumin@zinc-based organic framework DOI

Jiayi Qin,

Haiyan Zhang, Xianying Cao

et al.

Dalton Transactions, Journal Year: 2024, Volume and Issue: 54(3), P. 1256 - 1260

Published: Nov. 30, 2024

The elimination of S. aureus was achieved through the synergy chemo, photothermal therapy (PPT), and Zn 2+ .

Language: Английский

Citations

0