Enhancing the versatility of photocrosslinkable silk fibroin using an eco-friendly solvent DOI Creative Commons
Anne Katherine Brooks, Vamsi K. Yadavalli

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 10, 2024

Abstract Silk fibroin (SF), known for its biocompatibility and versatility, has been widely studied in tissue engineering biomedical devices. The modification of silk with photoreactive groups used to create novel biomaterials that undergo a liquid-to-solid transition upon exposure light, enabling precise control over structure formation, pore geometry, degradation. This advancement photofibroin (PF) shown the biofabrication hydrogels, 3D scaffolds, micro-patterned surfaces suitable applications, including scaffolds bioelectronics. Here, we present further improvement using water based ternary solvent calcium chloride-ethanol-water (Ajisawa reagent (AR)), dissolve photofibroin, offering sustainable alternative previously organic solvents. PF AR is be compatible various light-based manufacturing techniques soft lithography, photolithography, printing, fabrication multiscale structures high fidelity. gels formed demonstrate excellent cytocompatibility, supporting cell adhesion growth without additional coatings, making them ideal regenerative medicine. integration conductive polymers, such as PEDOT:PSS printable conducting gel opens possibilities research represents significant step forward employing versatile sustainable, high-performance biomaterial diverse applications.

Language: Английский

Enhancing the Versatility of Photocrosslinkable Silk Fibroin Using an Eco‐Friendly Solvent DOI Creative Commons
Anne Katherine Brooks, Vamsi K. Yadavalli

Advanced Engineering Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 15, 2025

Silk fibroin (SF), known for its biocompatibility and versatility, has been widely studied in tissue engineering biomedical devices. The modification of SF with photoreactive groups used to create novel biomaterials that undergo a liquid‐to‐solid transition upon exposure light, enabling precise control over structure formation, pore geometry, degradation. This advancement PF shown the biofabrication hydrogels, 3D scaffolds, micro‐patterned surfaces suitable applications, including scaffolds bioelectronics. Herein, further improvement using water‐based ternary solvent calcium chloride‐ethanol‐water (Ajisawa reagent (AR)) is presented, dissolve PF, offering sustainable alternative previously organic solvents. AR be compatible various light‐based manufacturing techniques soft lithography, photolithography, printing, fabrication multiscale structures high fidelity. gels formed demonstrate excellent cytocompatibility, supporting cell adhesion growth without additional coatings, making them ideal regenerative medicine. integration conductive polymers, such as PEDOT:PSS printable conducting gel opens possibilities research represents significant step forward employing versatile sustainable, high‐performance photoresin biomaterial diverse applications.

Language: Английский

Citations

0
DESIGN OF ULTRALIGHT MULTIFUNCTIONAL SANDWICH STRUCTURE WITH N-H HYBRID CORE FOR INTEGRATED SOUND ABSORPTION AND LOAD-BEARING CAPACITY DOI
Yongfeng Jiang, Xiangchao Feng, Jinling Gao

et al.

Materials Today Communications, Journal Year: 2024, Volume and Issue: 41, P. 110663 - 110663

Published: Oct. 10, 2024

Language: Английский

Citations

1
Vat Photopolymerization 3D Printing of High-Performance Ionic Organogel for Multifunctional Sensors DOI
Lei Chen, Fan Fu,

Pengshuai Wang

et al.

Materials Today Communications, Journal Year: 2024, Volume and Issue: 41, P. 110580 - 110580

Published: Sept. 30, 2024

Language: Английский

Citations

0
Enhancing the versatility of photocrosslinkable silk fibroin using an eco-friendly solvent DOI Creative Commons
Anne Katherine Brooks, Vamsi K. Yadavalli

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 10, 2024

Abstract Silk fibroin (SF), known for its biocompatibility and versatility, has been widely studied in tissue engineering biomedical devices. The modification of silk with photoreactive groups used to create novel biomaterials that undergo a liquid-to-solid transition upon exposure light, enabling precise control over structure formation, pore geometry, degradation. This advancement photofibroin (PF) shown the biofabrication hydrogels, 3D scaffolds, micro-patterned surfaces suitable applications, including scaffolds bioelectronics. Here, we present further improvement using water based ternary solvent calcium chloride-ethanol-water (Ajisawa reagent (AR)), dissolve photofibroin, offering sustainable alternative previously organic solvents. PF AR is be compatible various light-based manufacturing techniques soft lithography, photolithography, printing, fabrication multiscale structures high fidelity. gels formed demonstrate excellent cytocompatibility, supporting cell adhesion growth without additional coatings, making them ideal regenerative medicine. integration conductive polymers, such as PEDOT:PSS printable conducting gel opens possibilities research represents significant step forward employing versatile sustainable, high-performance biomaterial diverse applications.

Language: Английский

Citations

0