Recent Advances in Multifunctional Naturally Derived Bioadhesives for Tissue Engineering and Wound Management DOI
Aliakbar Jafari, Ahmed Al‐Ostaz, Sasan Nouranian

et al.

Polymers for Advanced Technologies, Journal Year: 2024, Volume and Issue: 35(12)

Published: Dec. 1, 2024

ABSTRACT Recent advancements in naturally derived bioadhesives have transformed their application across diverse medical fields, including tissue engineering, wound management, and surgery. This review focuses on the innovative development multifunctional nature of these bioadhesives, particularly emphasizing role enhancing adhesion performance wet environments optimizing mechanical properties for use dynamic tissues. Key areas covered include chemical physical mechanisms adhesion, incorporation multi‐adhesion strategies that combine covalent non‐covalent bonding, bioinspired designs mimicking natural adhesives such as those barnacles mussels. Additionally, discusses emerging applications regeneration musculoskeletal, cardiac, neural, ocular tissues, highlighting potential bioadhesive‐based therapies complex biological settings. Despite substantial progress, challenges scaling lab‐based innovations clinical overcoming environmental constraints remain critical. Ongoing research bioadhesive technologies aims to bridge gaps, promising significant improvements tailored therapeutic needs.

Language: Английский

Recent Advances in Multifunctional Naturally Derived Bioadhesives for Tissue Engineering and Wound Management DOI
Aliakbar Jafari, Ahmed Al‐Ostaz, Sasan Nouranian

et al.

Polymers for Advanced Technologies, Journal Year: 2024, Volume and Issue: 35(12)

Published: Dec. 1, 2024

ABSTRACT Recent advancements in naturally derived bioadhesives have transformed their application across diverse medical fields, including tissue engineering, wound management, and surgery. This review focuses on the innovative development multifunctional nature of these bioadhesives, particularly emphasizing role enhancing adhesion performance wet environments optimizing mechanical properties for use dynamic tissues. Key areas covered include chemical physical mechanisms adhesion, incorporation multi‐adhesion strategies that combine covalent non‐covalent bonding, bioinspired designs mimicking natural adhesives such as those barnacles mussels. Additionally, discusses emerging applications regeneration musculoskeletal, cardiac, neural, ocular tissues, highlighting potential bioadhesive‐based therapies complex biological settings. Despite substantial progress, challenges scaling lab‐based innovations clinical overcoming environmental constraints remain critical. Ongoing research bioadhesive technologies aims to bridge gaps, promising significant improvements tailored therapeutic needs.

Language: Английский

Citations

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