A Dual-Signal Electrochemiluminescence Sensor for Kanamycin Detection Based on a Self-Enhanced Zr MOF and Single Co-Reactant Competition Mechanism DOI Creative Commons

Yawen Zhu,

Xuemei Wang,

Zhiyong Yan

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(5), P. 291 - 291

Published: May 5, 2025

The dual-signal output self-calibration mode reduces the false positive and negative signals of electrochemiluminescence (ECL) aptamer sensors. A competitive ECL platform was designed for ultrasensitive detection kanamycin (KAN) using a zirconium metal–organic framework (Zr MOF) Luminol as emitters. To enhance efficiency, co-reactant (polyethyleneimine, PEI) covalently bound to Zr MOF achieve self-enhanced ECL. Based on selective interaction between KAN its aptamer, Luminol/KAN/Zr MOF-PEI “sandwich” structure immobilized electrode surface. competition PEI emitters increased signal decreased MOF’s signal. ratio in two enabled quantitative analysis KAN, achieving limit low 7.86 × 10−4 ng/mL. This study elucidated synergistic mechanism competition, offering novel approach constructing sensors single co-reactant.

Language: Английский

Bioinspired bi-amino acid Ce-MOFs Boosting oxidase-like Activity: Dual-mode Aflatoxin Detection, antimicrobial activity platform DOI
Yuxiang Wang, Yilin Zhao,

Qingyuan Tan

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 161977 - 161977

Published: March 1, 2025

Language: Английский

Citations

0
Nanoconfinement‐Enhanced Aggregation‐Induced Electrochemiluminescence for Smartphone‐Adopted Imaging Analysis of cTnI DOI
Chuanping Li, Zhen Yang, Jing Wang

et al.

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Abstract The domain‐limited catalytic enhancement has opened novel avenues for the advancement of highly efficient aggregation‐induced electrochemiluminescence (AIECL). Herein, a (ECL) sensing platform is constructed through in situ encapsulation emission (AIE) molecules, tetraphenylethylene, within metal‐organic frameworks (NH 2 ‐MIL‐88). These are uniquely enriched with atomically dispersed active sites that serve as nanoconfined co‐reactant accelerators. This innovative design leads to creation an integrated AIE nanoconfinement reactor. Within this reactor, accelerators catalyze co‐reactants into reactive species (RS) situ, facilitating direct interaction molecules spatially confined composite. Density functional theory calculations and electrochemical electron paramagnetic resonance demonstrate ECL attributed localized amplification, where space formed by coordination self‐assembly alters activation energy barriers improves absorption capacity catalyzing K S O 8 SO 4 ·‐ OH ·− . Additionally, utilizing MATLAB‐mediated image technology deep learning algorithms, smartphone‐adopted self‐reporting AIECL imaging system designed achieve accurate intelligent analysis cardiac troponin I (cTnI). method presents advanced strategy enhance local RS concentrations via catalysis. developed offers facile screening cTnI monitoring.

Language: Английский

Citations

0
Dual Enhanced Electrochemiluminescence using Aggregation Induction and Coraction Accelerator Strategies for Trace Determination of Acetamiprid DOI
Longchao Li,

Yuan Sun,

Di Zhang

et al.

Sensors and Actuators B Chemical, Journal Year: 2025, Volume and Issue: unknown, P. 137867 - 137867

Published: April 1, 2025

Language: Английский

Citations

0
A Dual-Signal Electrochemiluminescence Sensor for Kanamycin Detection Based on a Self-Enhanced Zr MOF and Single Co-Reactant Competition Mechanism DOI Creative Commons

Yawen Zhu,

Xuemei Wang,

Zhiyong Yan

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(5), P. 291 - 291

Published: May 5, 2025

The dual-signal output self-calibration mode reduces the false positive and negative signals of electrochemiluminescence (ECL) aptamer sensors. A competitive ECL platform was designed for ultrasensitive detection kanamycin (KAN) using a zirconium metal–organic framework (Zr MOF) Luminol as emitters. To enhance efficiency, co-reactant (polyethyleneimine, PEI) covalently bound to Zr MOF achieve self-enhanced ECL. Based on selective interaction between KAN its aptamer, Luminol/KAN/Zr MOF-PEI “sandwich” structure immobilized electrode surface. competition PEI emitters increased signal decreased MOF’s signal. ratio in two enabled quantitative analysis KAN, achieving limit low 7.86 × 10−4 ng/mL. This study elucidated synergistic mechanism competition, offering novel approach constructing sensors single co-reactant.

Language: Английский

Citations

0