Polymeric Microneedles for Biomedical Applications: Innovations in Transdermal Drug Delivery and Biosensing Technologies DOI
Wendel A. Alves, Jose E. U. Rojas,

Ana C. H. Castro-Kochi

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown

Published: April 4, 2025

Language: Английский

Nanotechnology-Based Wearable Electrochemical Biosensor for Disease Diagnosis DOI
Jinho Yoon,

Nayeon Kwon,

Yejin Lee

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: March 4, 2025

Recently, flexible electronics have significantly transformed information and communications technology (ICT). In particular, wearable devices, via integration with attachable biosensors, driven the development of new types biosensors diagnostic devices for point-of-care testing (POCT). Moreover, electrochemical can be applied to diagnose diseases in real time based on synergistic effect generated from incorporation technique. Besides, improve sensitivity while retaining their wearability, novel nanomaterials nanotechnologies been introduced. this review, recent studies nanotechnology-based accurate disease diagnosis are discussed. First, widely used techniques developing electrodes, including nanolithography- nano/microneedle-based patches, presented. Next, latest such as diabetes dermatitis discussed by categorizing into categories. Finally, review explores research trends application nanotechnology-enabled nanopatterning nano/microneedle technologies biosensors. This suggests approaches methods real-time under POCT applications.

Language: Английский

Citations

1

Smart Health Monitoring: Review of Electrochemical Biosensors for Cortisol Monitoring DOI
Zhijie Li, Dan Luo, Yaqian Zhang

et al.

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 18, 2025

Abstract Cortisol, also known as the stress hormone, is a crucial corticosteroid hormone that significantly increases secretion in human body when facing notable stress. Monitoring cortisol levels for personal management and diagnosis treatment of certain diseases. Electrochemical biosensors combine efficient sensitivity electrochemical technology with high specificity biological recognition processes, making them widely applicable analysis fluid components. This work outlines working mechanism biosensors, focusing particularly on sensing elements such antibodies, aptamers, molecularly imprinted polymers. It provides detailed explanations operational principles these different elements. summarizes evaluates latest advancements detecting fluids, discussing influence sensor design performance. Subsequently, through comparative various performances, further discusses challenges translating laboratory achievements into practical applications, including enhancing key metrics reusability, reproducibility, long‐term stability, continuous monitoring capability, response time. Finally, it offers insights recommendations achieving real‐time, continuous, biosensors.

Language: Английский

Citations

1

A Wearable Molecularly Imprinted Electrochemical Sensor for Cortisol Stable Monitoring in Sweat DOI Creative Commons

Yitao Chen,

Zidong He,

Yuanzhao Wu

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(3), P. 194 - 194

Published: March 18, 2025

Cortisol, a steroid hormone, is closely associated with human mental stress. The rapid, real-time, and continuous detection of cortisol using wearable devices offers promising approach for individual health. These must exhibit high sensitivity long-term stability to ensure reliable performance. This study developed electrochemical sensor based on molecularly imprinted polymer (MIP) technology real-time dynamic monitoring in sweat. A flexible gold (Au) electrode interfacial hydrophilic treatment was employed construct highly stable electrode. integration silk fibroin/polyvinylidene fluoride (SF/PVDF) composite membrane facilitates directional sweat transport, while liquid metal bonding enhances flexibility mechanical anti-delamination capability. exhibits an ultrawide range (0.1 pM 5 μM), selectivity (over 100-fold against interferents such as glucose lactic acid), (less than 3.76% signal attenuation over 120 cycles). Additionally, gradient modulus design implemented mitigate deformation interference under conditions. As device sweat, the sensor’s response aligns diurnal rhythm, offering sensitive interference-resistant solution health advancing personalized assessment stress-related disorders.

Language: Английский

Citations

1

Polymeric Microneedles for Biomedical Applications: Innovations in Transdermal Drug Delivery and Biosensing Technologies DOI
Wendel A. Alves, Jose E. U. Rojas,

Ana C. H. Castro-Kochi

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown

Published: April 4, 2025

Language: Английский

Citations

0