International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 144436 - 144436
Published: May 1, 2025
Language: Английский
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 144436 - 144436
Published: May 1, 2025
Language: Английский
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 304, P. 140774 - 140774
Published: Feb. 10, 2025
Language: Английский
Citations
1Frontiers in Neuroscience, Journal Year: 2025, Volume and Issue: 18
Published: Jan. 15, 2025
Intracerebral hemorrhage (ICH) is a major public health challenge worldwide, and associated with elevated rates of mortality, disability, morbidity, especially in low- middle-income nations. However, our knowledge the detailed molecular processes involved ICH remains insufficient, particularly those secondary injury stage, resulting lack effective treatments for ICH. Human platelet lysates (HPL) are abundant bioactive factors, numerous studies have demonstrated their beneficial effects on neurological diseases, including anti-neuroinflammatory ability, anti-oxidant effects, maintenance blood-brain barrier integrity, promotion neurogenesis. In this review, we thoroughly explore potential HPL treating from three critical perspectives: rationale selecting as treatment ICH, mechanisms through which contributes to management, additional measures necessary We elucidate role platelets pathophysiology highlight limitations current options advancements preclinical research application disorders. Furthermore, historical developments preparation methods field biomedicine discussed. Additionally, summarize molecules present therapeutic Finally, outline issues that must be addressed regarding utilizing modality
Language: Английский
Citations
0Archives of Pharmacal Research, Journal Year: 2025, Volume and Issue: unknown
Published: May 7, 2025
Language: Английский
Citations
0Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 107046 - 107046
Published: May 1, 2025
Language: Английский
Citations
0International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 144436 - 144436
Published: May 1, 2025
Language: Английский
Citations
0