The bowfin genome illuminates the developmental evolution of ray-finned fishes

Nature Genetics, Journal Year: 2021, Volume and Issue: 53(9), P. 1373 - 1384

Published: Aug. 30, 2021

Abstract The bowfin ( Amia calva ) is a ray-finned fish that possesses unique suite of ancestral and derived phenotypes, which are key to understanding vertebrate evolution. phylogenetic position as representative neopterygian fishes, its archetypical body plan unduplicated slowly evolving genome make central species for the genomic exploration fishes. Here we present chromosome-level assembly enables gene-order analyses, settling long-debated relationships. We examine chromatin accessibility gene expression through development investigate evolution immune, scale, respiratory fin skeletal systems identify hundreds gene-regulatory loci conserved across vertebrates. These resources connect developmental among bony further highlighting bowfin’s importance illuminating biology diversity in era.

Language: Английский

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A complete, telomere-to-telomere human genome sequence presents new opportunities for evolutionary genomics

Nature Methods, Journal Year: 2022, Volume and Issue: 19(6), P. 635 - 638

Published: June 1, 2022

Language: Английский

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Take a walk on the KRAB side

Trends in Genetics, Journal Year: 2023, Volume and Issue: 39(11), P. 844 - 857

Published: Sept. 14, 2023

Language: Английский

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Immunostimulant citrus fruit-derived extracellular vesicle nanodrugs for malignant glioma immunochemotherapy

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 484, P. 149463 - 149463

Published: Feb. 9, 2024

Language: Английский

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The genomes of all lungfish inform on genome expansion and tetrapod evolution

Nature, Journal Year: 2024, Volume and Issue: 634(8032), P. 96 - 103

Published: Aug. 14, 2024

Language: Английский

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The limb dorsoventral axis: Lmx1b's role in development, pathology, evolution, and regeneration

Developmental Dynamics, Journal Year: 2024, Volume and Issue: 253(9), P. 798 - 814

Published: Jan. 30, 2024

Abstract The limb anatomy displays well‐defined dorsal and ventral compartments, housing extensor, flexor muscles, which play a crucial role in facilitating locomotion manipulation. Despite its importance, the study of dorsoventral patterning has been relatively neglected compared to other two axes leaving many questions about genes developmental processes implicated unanswered. This review offers thorough overview current understanding patterning, synthesizing classical literature with recent research. It covers specification fate mesoderm subsequent translation into morphologies—a process directed by transcription factor Lmx1b. We also discuss potential evolution paired appendages delve involvement LMX1B Nail‐Patella syndrome, discussing molecular genetic aspects underlying this condition. Finally, polarity digit tip regeneration, prominent instance multi‐tissue regeneration mammals is considered. anticipate that will renew interest critical function evolutionary adaptations but nonetheless overlooked.

Language: Английский

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Chromosome-scale genome assembly reveals how repeat elements shape non-coding RNA landscapes active during newt limb regeneration

Cell Genomics, Journal Year: 2025, Volume and Issue: unknown, P. 100761 - 100761

Published: Jan. 1, 2025

Language: Английский

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Origin and stepwise evolution of vertebrate lungs

Nature Ecology & Evolution, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 14, 2025

Language: Английский

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The amphipod genome reveals population dynamics and adaptations to hadal environment

Cell, Journal Year: 2025, Volume and Issue: 188(5), P. 1378 - 1392.e18

Published: March 1, 2025

Language: Английский

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A brief review of vertebrate sex evolution with a pledge for integrative research: towards ‘sexomics’

Philosophical Transactions of the Royal Society B Biological Sciences, Journal Year: 2021, Volume and Issue: 376(1832), P. 20200426 - 20200426

Published: July 12, 2021

Triggers and biological processes controlling male or female gonadal differentiation vary in vertebrates, with sex determination (SD) governed by environmental factors simple to complex genetic mechanisms that evolved repeatedly independently various groups. Here, we review evolution across major clades of vertebrates information on SD, sexual development reproductive modes. We offer an up-to-date divergence times, species diversity, genomic resources, genome size, occurrence nature polyploids, SD systems, chromosomes, genes, dosage compensation sex-biased gene expression. Advances sequencing technologies now enable us study the at broader evolutionary scales, hope pursue a sexomics integrative research initiative vertebrates. The vertebrate sexome comprises interdisciplinary integrated differentiation, reproduction all levels, from genomes, transcriptomes proteomes, organs involved sex-specific processes, including gonads, secondary those transcriptional sex-bias. also includes ontogenetic behavioural aspects malfunction impairment fertility. Starting data generated high-throughput approaches, encourage others contribute expertise building understanding sexomes many key species. This article is part theme issue ‘Challenging paradigm chromosome evolution: empirical theoretical insights focus (Part I)’.

Language: Английский

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