7-Dehydrocholesterol is an endogenous suppressor of ferroptosis

Nature, Journal Year: 2024, Volume and Issue: 626(7998), P. 401 - 410

Published: Jan. 31, 2024

Language: Английский

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The roles of ferroptosis in cancer: Tumor suppression, tumor microenvironment, and therapeutic interventions

Cancer Cell, Journal Year: 2024, Volume and Issue: 42(4), P. 513 - 534

Published: April 1, 2024

Language: Английский

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Ferroptosis Detection: From Approaches to Applications

Angewandte Chemie International Edition, Journal Year: 2023, Volume and Issue: 62(35)

Published: Feb. 25, 2023

Abstract Understanding the intricate molecular machinery that governs ferroptosis and leveraging this accumulating knowledge could facilitate disease prevention, diagnosis, treatment, prognosis. Emerging approaches for in situ detection of major regulators biological events across cellular, tissue, living subjects provide a multiscale perspective studying ferroptosis. Furthermore, advanced applications integrate latest technologies hold tremendous promise research. In review, we first briefly summarize mechanisms key underlying Ferroptosis are then presented to delineate their design, action, applications. Special interest is placed on multifunctional platforms. Finally, discuss prospects challenges applications, with aim providing roadmap theranostic development broad range ferroptosis‐related diseases.

Language: Английский

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Ferroptosis: A flexible constellation of related biochemical mechanisms

Molecular Cell, Journal Year: 2023, Volume and Issue: 83(7), P. 1030 - 1042

Published: March 27, 2023

Language: Английский

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Disulfidptosis: disulfide stress–induced cell death

Trends in Cell Biology, Journal Year: 2023, Volume and Issue: 34(4), P. 327 - 337

Published: Aug. 12, 2023

Language: Английский

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