Biological Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 14, 2025
Abstract
Heat
stress
transcription
factors
(HSFs)
play
a
pivotal
role
in
regulating
plant
responses
to
heat
and
other
environmental
stresses,
as
well
developmental
processes.
HSFs
possess
conserved
domains
responsible
for
DNA
binding,
oligomerization,
transcriptional
regulation,
which
collectively
enable
precise
dynamic
control
of
cellular
stimuli.
Functional
diversification
has
been
demonstrated
through
genetic
studies
model
plants
such
Arabidopsis
thaliana
economically
important
crops
like
tomato,
rice,
wheat.
However,
the
underlying
molecular
mechanisms
that
govern
HSF
function
remain
only
partially
understood,
handful
HSFs.
Advancements
structural
biology,
biochemistry,
genomics
shed
light
into
how
mediate
at
level.
These
insights
offer
exciting
opportunities
leverage
biology
gene
editing
crop
improvement,
enabling
customization
tolerance
traits
via
regulation
HSF-dependent
regulatory
networks
enhance
thermotolerance.
This
review
synthesizes
current
knowledge
on
structure
function,
providing
perspective
their
roles
adaptation
changing
climate.
Journal of Translational Medicine,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: Dec. 20, 2024
Abstract
CRISPR-based
gene
editing
technology
theoretically
allows
for
precise
manipulation
of
any
genetic
target
within
living
cells,
achieving
the
desired
sequence
modifications.
This
revolutionary
advancement
has
fundamentally
transformed
field
biomedicine,
offering
immense
clinical
potential
treating
and
correcting
disorders.
In
treatment
most
diseases,
genome
that
avoids
generation
mixed
byproducts
is
considered
ideal
approach.
article
reviews
current
progress
base
editors
prime
editors,
elaborating
on
specific
examples
their
applications
in
therapeutic
field,
highlights
opportunities
improvement.
Furthermore,
we
discuss
performance
these
technologies
terms
safety
efficacy
applications,
analyze
latest
advancements
directions
could
influence
future
development
technologies.
Our
goal
to
outline
relevance
this
rapidly
evolving
scientific
preview
a
roadmap
successful
DNA
therapies
hereditary
or
idiopathic
diseases.
Stress Biology,
Journal Year:
2025,
Volume and Issue:
5(1)
Published: Jan. 26, 2025
Abstract
Plants,
as
sessile
organisms,
must
adapt
to
a
range
of
abiotic
stresses,
including
drought,
salinity,
heat,
and
cold,
which
are
increasingly
exacerbated
by
climate
change.
These
stresses
significantly
impact
crop
productivity,
posing
challenges
for
sustainable
agriculture
food
security.
Recent
advances
in
omics
studies
genetics
have
shed
light
on
molecular
mechanisms
underlying
plant
stress
responses,
the
role
calcium
(Ca
2
⁺)
signaling,
liquid–liquid
phase
separation
(LLPS),
cell
wall-associated
sensors
detecting
responding
environmental
changes.
However,
gaps
remain
understanding
how
rapid
signaling
is
integrated
with
slower,
adaptive
processes.
Emerging
evidence
also
highlights
crosstalk
between
immunity,
growth
regulation,
mediated
key
components
such
RAF-SnRK2
kinase
cascades,
DELLA
proteins,
etc.
Strategies
enhance
resistance
without
compromising
yield
include
introducing
beneficial
alleles,
spatiotemporal
optimization
decoupling
from
inhibition.
This
review
emphasizes
importance
interdisciplinary
approaches
innovative
technologies
bridge
fundamental
research
practical
agricultural
applications,
aiming
develop
resilient
crops
production
an
era
escalating
challenges.
Agriculture,
Journal Year:
2025,
Volume and Issue:
15(3), P. 318 - 318
Published: Jan. 31, 2025
Global
warming
affects
crop
growth
and
development,
threatening
food
security.
As
one
of
the
essential
crops,
rice
is
severely
affected
by
high
temperature
stress,
which
compromises
both
its
yield
quality.
Therefore,
gaining
a
deep
understanding
molecular
mechanisms
responds
to
heat
stress
breeding
varieties
that
are
tolerant
such
crucial
for
maintaining
This
review
summarizes
impacts
on
quality-related
traits
at
different
development
stages
rice,
perception
response
improvement
in
heat-tolerant
using
existing
superior
alleles/QTLs.
We
also
discuss
opportunities
challenges
creating
highly
germplasm,
providing
new
ideas
insights
future
varieties.
Cell Reports,
Journal Year:
2025,
Volume and Issue:
44(3), P. 115390 - 115390
Published: March 1, 2025
SummaryClimate-change-induced
extreme
heat
and
drought
increasingly
threaten
plant
growth
development,
with
a
particularly
significant
impact
on
sexual
reproduction.
Heat
stress
can
disrupt
key
stages
of
reproduction,
including
flowering
time,
gametophyte
pollination,
seed
formation,
leading
to
infertility
substantial
yield
reductions
in
crops.
This
review
systematically
summarizes
the
latest
research
effects
various
reproduction
proposes
specific
strategies
mitigate
agricultural
hazards
posed
by
these
stresses.
By
providing
an
in-depth
analysis
underlying
mechanisms
regulatory
networks,
this
offers
theoretical
basis
for
advancing
fundamental
optimizing
practices
address
severe
challenges
climate
change
presents
agriculture.Graphical
abstract
Journal of Integrative Plant Biology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 18, 2025
ABSTRACT
The
modern
cultivated
tomato
(
Solanum
lycopersicum
)
was
domesticated
from
pimpinellifolium
native
to
the
Andes
Mountains
of
South
America
through
a
“two‐step
domestication”
process.
It
introduced
Europe
in
16th
century
and
later
widely
worldwide.
Since
late
19th
century,
breeders,
guided
by
genetics,
breeding
science,
statistical
theory,
have
improved
tomatoes
into
an
important
fruit
vegetable
crop
that
serves
both
fresh
consumption
processing
needs,
satisfying
diverse
consumer
demands.
Over
past
three
decades,
advancements
molecular
technologies,
represented
marker
technology,
genome
sequencing,
editing,
significantly
transformed
paradigms.
This
article
reviews
research
progress
field
breeding,
encompassing
sequencing
germplasm
resources,
identification
functional
genes
for
agronomic
traits,
development
key
technologies.
Based
on
these
advancements,
we
also
discuss
major
challenges
perspectives
this
field.
Frontiers in Genome Editing,
Journal Year:
2025,
Volume and Issue:
7
Published: March 18, 2025
Climate
change
is
a
global
concern
for
agriculture,
food
security,
and
human
health.
It
affects
several
crops
causes
drastic
losses
in
yield,
leading
to
severe
disturbances
the
economy,
environment,
community.
The
consequences
on
important
staple
crops,
such
as
rice,
maize,
wheat,
will
worsen
create
insecurity
across
globe.
Although
various
methods
of
trait
improvements
are
available
being
used,
clustered
regularly
interspaced
short
palindromic
repeats
CRISPR-associated
protein
9
(CRISPR/Cas9)
mediated
genome
manipulation
have
opened
new
avenue
functional
genomics
crop
improvement.
This
review
discuss
progression
improvement
from
conventional
breeding
advanced
editing
techniques
how
CRISPR/Cas9
technology
can
be
applied
enhance
tolerance
main
cereal
(wheat,
maize)
against
any
harsh
climates.
CRISPR/Cas
endonucleases
their
derived
genetic
engineering
tools
possess
high
accuracy,
versatile,
more
specific,
easy
design,
climate-smart
or
resilient
combat
survive
environments.
CRISPR/Cas9-mediated
approach
has
been
make
them
climate
resilient.
review,
supported
by
bibliometric
analysis
recent
literature,
highlights
potential
target
genes/traits
addresses
significance
gene
technologies
tackling
vulnerable
effects
major
maize.
