Viruses,
Journal Year:
2024,
Volume and Issue:
16(11), P. 1737 - 1737
Published: Nov. 5, 2024
This
study
provides
an
in-depth
analysis
of
mpox,
encompassing
its
history,
characteristics,
epidemiology,
diagnostics,
treatment
options,
and
the
ongoing
evolution
virus
transmission
dynamics.
Mpox,
though
once
successfully
eradicated,
has
re-emerged
with
new
modes
a
broader
host
range.
Genomic
analyses
have
revealed
virus's
adaptability,
posing
challenges
for
diagnostics
vaccine
efficacy.
The
epidemiology
shifted
from
sporadic
zoonotic
in
rural
Africa
to
significant
presence
urban
areas,
particularly
impacting
high-risk
populations.
Advancements
therapeutics
offer
hope,
but
persist.
work
underscores
critical
need
enhanced
surveillance,
vaccination
strategies,
continued
research
bolster
global
health
systems
preparedness
future
outbreaks.
Deleted Journal,
Journal Year:
2024,
Volume and Issue:
21(1)
Published: Oct. 15, 2024
Abstract
The
threat
of
the
emergence
potential
pandemics
in
future
has
been
looming
ever
since
world
witnessed
worst-ever
public
health
catastrophe
following
coronavirus
disease
2019
(COVID-19)
pandemic
caused
by
novel
severe
acute
respiratory
syndrome
coronavirus-2
(SARS-CoV-2).
COVID-19
affected
billions
people
killing
millions
throughout
world.
Now,
we
have
noticing
an
alarming
rise
cases
mpox
Mpox
virus
(MPXV).
Although
discovered
1958,
was
largely
confined
to
monkeys
before
causing
first
human
infection
1970.
MPXV
is
demonstrating
a
complex
transmission
behavior
as
noted
its
discovery
Denmark
imported
from
Singapore
(Asia)
and
later
spreading
humans
repeated
re-emergence.
African
nations
including
Democratic
Republic
Congo
(DRC)
reemerging
United
States
America
2003
affecting
several
who
had
history
contact
with
animals.
Following
scattered
reports
endemic
regions,
appears
remerged
after
approximately
two
decades
2022
involving
(USA)
European
countries.
across
globe
evidenced
60
countries
more
than
120
current
year.
It
therefore
essential
improve
understanding
MPXV,
epidemiology,
pathogenicity
virulence,
clinical
features,
control
preventive
measures
increase
preparedness
efficiently
tackle
any
emergency.
Pakistan Journal of Health Sciences,
Journal Year:
2024,
Volume and Issue:
unknown, P. 03 - 12
Published: Sept. 30, 2024
Monkeypox
was
caused
by
Virus
(MPXV)
and
can
infect
both
humans
animals.
An
understanding
of
the
interplay
between
host
immunity
genetic
diversity
necessary
to
understand
etiology
epidemiology
monkeypox
disease.
Objective:
To
clarify
how
differences
immune
responses
interact
when
a
moneypox
infection
occurs.
Furthermore,
we
also
aim
provide
insights
into
individual
variability
in
illness
outcomes
possible
treatment
targets
investigating
distinct
profiles
affect
system
activation
efficacy.
Methods:
Recent
research
on
monkeypox,
concentrating
response
mechanisms
variables
linked
virus
vulnerability
have
thoroughly
analyzed.
For
this
purpose,
data
were
searched
from
various
engines
such
as
google
scholar,
pubmed,
medline
etc.,
using
different
key
words
i.e.,
immunity,
antibodies
interactions,
outbreak,
mnkeypox
strains.
Conclusions:
The
way
progresses
turns
out
greatly
influenced
immunological
responses.
Public
health
initiatives
creation
tailored
plans
benefit
identification
markers
vulnerability.
PeerJ,
Journal Year:
2024,
Volume and Issue:
12, P. e18313 - e18313
Published: Oct. 30, 2024
The
ongoing
high
occurrence
of
harmful
infectious
diseases
significantly
threatens
human
health.
Existing
methods
used
to
control
such
primarily
involve
targeting
the
pathogens,
usually
neglecting
vital
role
host
factors
in
disease
advancement.
Gamma
delta
(γδ)
T
cells
act
as
a
bridge
between
innate
and
adaptive
immunity,
playing
crucial
combating
pathogen
invasion.
Among
these
γδT
cell
subsets,
which
are
categorized
based
on
receptor
variable
expression
patterns,
V
(δ)
1
Viruses,
Journal Year:
2024,
Volume and Issue:
16(11), P. 1737 - 1737
Published: Nov. 5, 2024
This
study
provides
an
in-depth
analysis
of
mpox,
encompassing
its
history,
characteristics,
epidemiology,
diagnostics,
treatment
options,
and
the
ongoing
evolution
virus
transmission
dynamics.
Mpox,
though
once
successfully
eradicated,
has
re-emerged
with
new
modes
a
broader
host
range.
Genomic
analyses
have
revealed
virus's
adaptability,
posing
challenges
for
diagnostics
vaccine
efficacy.
The
epidemiology
shifted
from
sporadic
zoonotic
in
rural
Africa
to
significant
presence
urban
areas,
particularly
impacting
high-risk
populations.
Advancements
therapeutics
offer
hope,
but
persist.
work
underscores
critical
need
enhanced
surveillance,
vaccination
strategies,
continued
research
bolster
global
health
systems
preparedness
future
outbreaks.
