The gut microbiome of healthy Japanese and its microbial and functional uniqueness DOI Creative Commons
Suguru Nishijima, Wataru Suda, Kenshiro Oshima

et al.

DNA Research, Journal Year: 2016, Volume and Issue: 23(2), P. 125 - 133

Published: March 6, 2016

The human gut microbiome has profound influences on the host's health largely through its interference with various intestinal functions. As recent studies have suggested diversity in among populations, it will be interesting to analyse how is correlated geographical, cultural, and traditional differences. Japanese people are known several characteristic features such as eating a variety of foods exhibiting low BMI long life span. In this study, we analysed microbiomes by comparing metagenomic data obtained from 106 individuals those 11 other nations. We found that composition showed more abundant phylum Actinobacteria, particular genus Bifidobacterium, than Regarding microbial functions, carbohydrate metabolism were overrepresented concurrent decrease for replication repair, cell motility. remarkable prevalence genes methanogenesis significant depletion archaeon Methanobrevibacter smithii enrichment acetogenesis compared others difference hydrogen pathway between them. It thus seems considerably different which cannot simply explained diet alone. postulate possible existence hitherto unknown factors contributing population-level microbiomes.

Language: Английский

Population-level analysis of gut microbiome variation DOI
Gwen Falony, Marie Joossens, Sara Vieira‐Silva

et al.

Science, Journal Year: 2016, Volume and Issue: 352(6285), P. 560 - 564

Published: April 28, 2016

“Normal” for the gut microbiota For benefit of future clinical studies, it is critical to establish what constitutes a “normal” microbiome, if exists at all. Through fecal samples and questionnaires, Falony et al. Zhernakova targeted general populations in Belgium Netherlands, respectively. Gut composition correlated with range factors including diet, use medication, red blood cell counts, chromogranin A, stool consistency. The data give some hints possible biomarkers normal communities. Science , this issue pp. 560 565

Language: Английский

Citations

1991

Stochastic Community Assembly: Does It Matter in Microbial Ecology? DOI Open Access
Jizhong Zhou, Daliang Ning

Microbiology and Molecular Biology Reviews, Journal Year: 2017, Volume and Issue: 81(4)

Published: Oct. 12, 2017

Understanding the mechanisms controlling community diversity, functions, succession, and biogeography is a central, but poorly understood, topic in ecology, particularly microbial ecology. Although stochastic processes are believed to play nonnegligible roles shaping structure, their importance relative deterministic hotly debated. The of ecological stochasticity structure far less appreciated. Some main reasons for such heavy debates difficulty defining diverse methods used delineating stochasticity. Here, we provide critical review synthesis data from most recent studies on assembly We then describe both components embedded various processes, including selection, dispersal, diversification, drift. also different approaches inferring observational diversity patterns highlight experimental communities. In addition, research challenges, gaps, future directions research.

Language: Английский

Citations

1972

Diet–microbiota interactions as moderators of human metabolism DOI
Justin L. Sonnenburg, Fredrik Bäckhed

Nature, Journal Year: 2016, Volume and Issue: 535(7610), P. 56 - 64

Published: July 5, 2016

Language: Английский

Citations

1900

The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease DOI Creative Commons

Kassem Makki,

Edward C. Deehan, Jens Walter

et al.

Cell Host & Microbe, Journal Year: 2018, Volume and Issue: 23(6), P. 705 - 715

Published: June 1, 2018

Language: Английский

Citations

1884

Diet-induced extinctions in the gut microbiota compound over generations DOI
Erica D. Sonnenburg, Samuel A. Smits, Mikhail Tikhonov

et al.

Nature, Journal Year: 2016, Volume and Issue: 529(7585), P. 212 - 215

Published: Jan. 13, 2016

Language: Английский

Citations

1496

You are what you eat: diet, health and the gut microbiota DOI
Niv Zmora, Jotham Suez, Eran Elinav

et al.

Nature Reviews Gastroenterology & Hepatology, Journal Year: 2018, Volume and Issue: 16(1), P. 35 - 56

Published: Sept. 27, 2018

Language: Английский

Citations

1334

Salt-responsive gut commensal modulates TH17 axis and disease DOI
Nicola Wilck,

Mariana Matus,

Sean M. Kearney

et al.

Nature, Journal Year: 2017, Volume and Issue: 551(7682), P. 585 - 589

Published: Nov. 1, 2017

Language: Английский

Citations

1086

Genetic Determinants of the Gut Microbiome in UK Twins DOI Creative Commons
Julia K. Goodrich, Emily Davenport, Michelle Beaumont

et al.

Cell Host & Microbe, Journal Year: 2016, Volume and Issue: 19(5), P. 731 - 743

Published: May 1, 2016

Language: Английский

Citations

952

Gut microbial metabolites as multi-kingdom intermediates DOI
Kimberly A. Krautkramer, Jing Fan, Fredrik Bäckhed

et al.

Nature Reviews Microbiology, Journal Year: 2020, Volume and Issue: 19(2), P. 77 - 94

Published: Sept. 23, 2020

Language: Английский

Citations

909

Human gut microbiota/microbiome in health and diseases: a review DOI
Eman Zakaria Gomaa

Antonie van Leeuwenhoek, Journal Year: 2020, Volume and Issue: 113(12), P. 2019 - 2040

Published: Nov. 2, 2020

Language: Английский

Citations

903