Sensory Plasticity Caused by Up-down Regulation Encodes the Information of Short-term Learning and Memory DOI
Zheng‐Xing Wu,

Ping-Zhou Wang,

Ming-Hai Ge

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 24, 2024

Abstract Learning and memory are essential for animals’ well-being surviving. The underlying mechanisms a major task of neuroscience studies. In this study, we identified circuit consisting ASER, RIC, RIS, AIY, required short-term salt chemotaxis learning (SCL) in C. elegans. ASER NaCl sensation possesses ON- OFF-responses is remodeled by conditioning. RIC integrates sensory information stimulation food deprivation generates suppression its calcium response plasticity combining with interaction between RIS that recalling. We further identify the signaling pathways neurons circuit: tyramine/TYRA-2 octopamine/OCTR-1 mediate neurohumoral regulation AIY RIC; FLP-14/FRPR-10 PDF-2/PDFR-1 signalings transmission humoral from to feedback respectively. Thus, encodes SCL, which can facilitate animal adaptation dynamic environments.

Language: Английский

Sensory Plasticity Caused by Up-down Regulation Encodes the Information of Short-term Learning and Memory DOI
Zheng‐Xing Wu,

Ping-Zhou Wang,

Ming-Hai Ge

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 24, 2024

Abstract Learning and memory are essential for animals’ well-being surviving. The underlying mechanisms a major task of neuroscience studies. In this study, we identified circuit consisting ASER, RIC, RIS, AIY, required short-term salt chemotaxis learning (SCL) in C. elegans. ASER NaCl sensation possesses ON- OFF-responses is remodeled by conditioning. RIC integrates sensory information stimulation food deprivation generates suppression its calcium response plasticity combining with interaction between RIS that recalling. We further identify the signaling pathways neurons circuit: tyramine/TYRA-2 octopamine/OCTR-1 mediate neurohumoral regulation AIY RIC; FLP-14/FRPR-10 PDF-2/PDFR-1 signalings transmission humoral from to feedback respectively. Thus, encodes SCL, which can facilitate animal adaptation dynamic environments.

Language: Английский

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