MXene-Chitosan Composites and Their Biomedical Potentials

Micromachines, Journal Year: 2022, Volume and Issue: 13(9), P. 1383 - 1383

Published: Aug. 25, 2022

Today, MXenes with fascinating electronic, thermal, optical, and mechanical features have been broadly studied for biomedical applications, such as drug/gene delivery, photothermal/photodynamic therapy, antimicrobials/antivirals, sensing, tissue engineering, regenerative medicine. In this context, various MXene-polymer composites designed to improve the characteristics physiological stability, sustained/controlled release behaviors, biodegradability, biocompatibility, selectivity/sensitivity, functionality. Chitosan advantages of ease modification, antibacterial activities, non-toxicity, biocompatibility can be considered attractive materials designing hybridized together MXenes. These hybrid ought further explored applications because their unique properties high photothermal conversion efficiency, improved stimuli-responsiveness superior features. structural, functional, biological attributes indicate that MXene-chitosan are alternatives in engineering. However, several crucial aspects regarding surface functionalization/modification, hybridization, nanotoxicological analyses, long-term biosafety assessments, vitro/in vivo evaluations, identification optimization conditions, implementation environmentally-benign synthesis techniques, clinical translation studies still need examined by researchers. Although very limited revealed great potentials hybrids biomedicine, next steps should toward extensive research detailed analyses optimizing improving functionality a industrial outlook. Herein, recent developments use deliberated, focus on important challenges future perspectives. view multifunctionality composites, these open significant new opportunities bio- nano-medicine arena.

Language: Английский

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Progress, challenges, and opportunities of two-dimensional layered materials based electrochemical sensors and biosensors

Materials Today Chemistry, Journal Year: 2022, Volume and Issue: 26, P. 101235 - 101235

Published: Nov. 12, 2022

Language: Английский

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Advanced Nanosystems for Cancer Therapeutics: A Review

ACS Applied Nano Materials, Journal Year: 2023, Volume and Issue: 6(9), P. 7123 - 7149

Published: April 25, 2023

Since cancer has a very complex pathophysiology, existing treatment strategies encounter several challenges such as the lack of specificity/selectivity, induction multidrug resistance, and possible side effects/toxicity. A wide variety organic, inorganic, hybrid nanosystems have been designed with unique magnetic, thermal, mechanical, electrical, optical properties for targeted therapy. These advanced enhanced bioavailability, biocompatibility, drug loading capacity developed therapy to reduce toxicity improve targeting properties. In this context, persist their clinical translational studies enhancement therapeutic efficiency well optimization synthesis conditions large-scale production. addition, despite promising preclinical results, number available patients is still low, partly due understanding differences among animal model species humans that influence behavior functionality these nanosystems. Regarding this, organ-on-a-chip platforms can significantly help in screening delivery aspects cancer/tumor cells modeling research; organs-on-chip approach also be helpful analyze cancer–immune interactions. Future should focus on exploration multifunctional synergistic chemo-photothermal, photothermal/photodynamic, immunotherapeutic potentials smart theranostic capabilities. Herein, recent advancements pertaining applications therapeutics are deliberated. Current obstacles limitations hindering application from research uses discussed while providing recommendations more efficient adoption nanomaterials cancers.

Language: Английский

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Several Fundamental Aspects of MXene: Synthesis and Their Applications

ChemistrySelect, Journal Year: 2023, Volume and Issue: 8(30)

Published: Aug. 8, 2023

Abstract MXene, a new member of the 2D material family, has stimulated research and been used in variety fields since its inception. It is two dimensional transition metal‐based layered made carbides nitrides. From beginning discovery, specific etching MAX phase various predecessors have employed to generate distinct compositions, with several compositions being theoretically envisaged. Due their unique features, MXene family prospective contender for applications, including, interference shielding by electromagnet, energy storage, electrocatalysis, water purification, environmental remediation, medicine so on. The pure as well based materials can be easily prepared from phases easy implementation broad range areas. review article includes properties, synthesis, selection precursor materials, commonly preparation methods MXene. A few applications covered this review. Additionally, limitations future prospects MXene‐based compounds discussed.

Language: Английский

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MXene-based composites in smart wound healing and dressings

Nanoscale Advances, Journal Year: 2024, Volume and Issue: 6(14), P. 3513 - 3532

Published: Jan. 1, 2024

Recent advancements in MXene-based wound dressings are discussed, focusing on their contributions to tissue regeneration, infection control, anti-inflammation and photothermal effects, targeted therapeutic delivery.

Language: Английский

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