Optimization of the structure of three-dimensional interconnected porous carbonate apatite bone grafts with spherical granules DOI Open Access

Saki Takeda,

Akira Tsuchiya, Masafumi Moriyama

et al.

Dental Materials Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A block-type of three-dimensional carbonate apatite bone graft (3D-CO3Ap) is demanded for applying large defects. Although we fabricated the 3D-CO3Ap with high mechanical strength by fusing polymer-bound spherical precursor, optimized condition has not yet been found. In this study, indicated controlling granular packing ratio (i.e., different compression ratios mold volume from 100% to 140%). was obtained in 110% 130%, even though block collapsed and complete conversion CO3Ap achieved 140%. The highest compressive 130% because intergranular connection area most enhanced. Furthermore, when reconstructing defects, prevented soft tissue penetration showed good osteoconductivity their controlled pore size. optimal achieving both osteoconductivity.

Language: Английский

Optimization of the structure of three-dimensional interconnected porous carbonate apatite bone grafts with spherical granules DOI Open Access

Saki Takeda,

Akira Tsuchiya, Masafumi Moriyama

et al.

Dental Materials Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A block-type of three-dimensional carbonate apatite bone graft (3D-CO3Ap) is demanded for applying large defects. Although we fabricated the 3D-CO3Ap with high mechanical strength by fusing polymer-bound spherical precursor, optimized condition has not yet been found. In this study, indicated controlling granular packing ratio (i.e., different compression ratios mold volume from 100% to 140%). was obtained in 110% 130%, even though block collapsed and complete conversion CO3Ap achieved 140%. The highest compressive 130% because intergranular connection area most enhanced. Furthermore, when reconstructing defects, prevented soft tissue penetration showed good osteoconductivity their controlled pore size. optimal achieving both osteoconductivity.

Language: Английский

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