Mixing Times of Miscible Liquid Systems in Agitated Vessels DOI Open Access
Russell Miller,

Isabella Cardona Barber,

Leo Lue

et al.

Processes, Journal Year: 2025, Volume and Issue: 13(4), P. 1083 - 1083

Published: April 3, 2025

A better understanding of mixing times for mixed solvent systems in laboratory-scale vessels is crucial improving mixing-sensitive processes such as antisolvent crystallisation. Whilst agitated has been extensively studied using solutions additives the same solvent, there very limited literature on different miscible solvents and none which would be relevant to crystallisation processes. In this work, water–ethanol a 1 litre vessel, by pitched blade impeller with probes used baffles, were investigated transitional flow regime both experimental computational fluid dynamics (CFD) approaches. We two scenarios: adding sodium chloride tracer premixed ethanol containing water. Mixing was experimentally through conductivity measurements computationally large eddy simulations M-Star CFD software package. Empirical correlations from Dynochem engineering toolbox also comparison. The results showed significant run-to-run variability experiments simulations, ranges being notably wider than ones under given conditions. While consistent across compositions, decreased increasing content. approximately inversely proportional speed. indicated that 25–40 rotations required homogenisation, while needed 25–100 rotations. predicted 40 rotations, independent speed, but could not capture inherent times.

Language: Английский

Mixing Times of Miscible Liquid Systems in Agitated Vessels DOI Open Access
Russell Miller,

Isabella Cardona Barber,

Leo Lue

et al.

Processes, Journal Year: 2025, Volume and Issue: 13(4), P. 1083 - 1083

Published: April 3, 2025

A better understanding of mixing times for mixed solvent systems in laboratory-scale vessels is crucial improving mixing-sensitive processes such as antisolvent crystallisation. Whilst agitated has been extensively studied using solutions additives the same solvent, there very limited literature on different miscible solvents and none which would be relevant to crystallisation processes. In this work, water–ethanol a 1 litre vessel, by pitched blade impeller with probes used baffles, were investigated transitional flow regime both experimental computational fluid dynamics (CFD) approaches. We two scenarios: adding sodium chloride tracer premixed ethanol containing water. Mixing was experimentally through conductivity measurements computationally large eddy simulations M-Star CFD software package. Empirical correlations from Dynochem engineering toolbox also comparison. The results showed significant run-to-run variability experiments simulations, ranges being notably wider than ones under given conditions. While consistent across compositions, decreased increasing content. approximately inversely proportional speed. indicated that 25–40 rotations required homogenisation, while needed 25–100 rotations. predicted 40 rotations, independent speed, but could not capture inherent times.

Language: Английский

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