Cell Reports Medicine,
Journal Year:
2021,
Volume and Issue:
2(8), P. 100369 - 100369
Published: July 21, 2021
There
is
an
urgent
need
to
identify
which
COVID-19
patients
will
develop
life-threatening
illness
so
that
medical
resources
can
be
optimally
allocated
and
rapid
treatment
administered
early
in
the
disease
course,
when
clinical
management
most
effective.
To
aid
prognostic
classification
of
severity,
we
perform
untargeted
metabolomics
on
plasma
from
339
patients,
with
samples
collected
at
six
longitudinal
time
points.
Using
temporal
metabolic
profiles
machine
learning,
build
a
predictive
model
severity.
We
discover
panel
metabolites
measured
study
entry
successfully
determines
Through
analysis
samples,
confirm
these
markers
are
directly
related
progression
their
levels
return
baseline
upon
recovery.
Finally,
validate
also
altered
hamster
COVID-19.
arXiv (Cornell University),
Journal Year:
2021,
Volume and Issue:
unknown
Published: Jan. 1, 2021
AI
is
undergoing
a
paradigm
shift
with
the
rise
of
models
(e.g.,
BERT,
DALL-E,
GPT-3)
that
are
trained
on
broad
data
at
scale
and
adaptable
to
wide
range
downstream
tasks.
We
call
these
foundation
underscore
their
critically
central
yet
incomplete
character.
This
report
provides
thorough
account
opportunities
risks
models,
ranging
from
capabilities
language,
vision,
robotics,
reasoning,
human
interaction)
technical
principles(e.g.,
model
architectures,
training
procedures,
data,
systems,
security,
evaluation,
theory)
applications
law,
healthcare,
education)
societal
impact
inequity,
misuse,
economic
environmental
impact,
legal
ethical
considerations).
Though
based
standard
deep
learning
transfer
learning,
results
in
new
emergent
capabilities,and
effectiveness
across
so
many
tasks
incentivizes
homogenization.
Homogenization
powerful
leverage
but
demands
caution,
as
defects
inherited
by
all
adapted
downstream.
Despite
impending
widespread
deployment
we
currently
lack
clear
understanding
how
they
work,
when
fail,
what
even
capable
due
properties.
To
tackle
questions,
believe
much
critical
research
will
require
interdisciplinary
collaboration
commensurate
fundamentally
sociotechnical
nature.
Results in Physics,
Journal Year:
2020,
Volume and Issue:
21, P. 103746 - 103746
Published: Dec. 25, 2020
After
the
spread
of
SARS-CoV-2
epidemic
out
China,
evolution
in
pandemic
worldwide
shows
dramatic
differences
among
countries.
In
Europe,
situation
Italy
first
and
later
Spain
has
generated
great
concen,
despite
other
countries
show
better
prospects,
large
uncertainties
yet
remain
on
future
efficacy
containment,
mitigation,
or
attack
strategies.
This
Manuscript
was
originally
written
last
days
March
as
a
way
to
report
current
wave
pandemic.
The
results
were
updated
several
times
for
also
month
July.
Here
we
applied
modified
SEIR
compartmental
model
accounting
infection
during
latent
period,
which
incorporate
effects
varying
proportions
containment.
We
fit
data
reported
infected
populations
at
beginning
peak
account
case
reporting
study
scenario
projections
individual
regions
(CCAA).
aim
this
it's
evaluate
confinement
rate
stages
outbreak
order
assess
scenarios
that
minimize
incidence
but
mortality.
Results
indicate
with
23,
epidemics
follow
an
similar
isolation
1,5
percent
population,
if
there
no
intervention
actions
it
might
reach
maximum
over
1.4M
around
April
27.
effect
ongoing
partial
measures
is
unknown
(an
update
until
31st
included),
increasing
ten
more
could
drastically
reduce
100k
cases
by
early
April,
while
each
day
delay
taking
hard
containment
represents
90
increase
population
peak.
Dynamics
sub
aggregated
levels
CCAA
different
progression
most
worrying
Madrid
Catalonia.
Increasing
alpha
values
up
10
times,
addition
drastic
reduction
clinical
cases,
would
than
half
number
deaths.
Updates
simulations
substantial
burden
underway.
A
approach
conducted
pre-and
post-intervention
begins
suggest
both
deaths
been
achieved,
showing
social
distancing
interventions.
By
real
end
May
July
calculate
from
compare
formulated
March.
IETE Technical Review,
Journal Year:
2021,
Volume and Issue:
39(4), P. 775 - 788
Published: May 23, 2021
In
the
Internet
of
Medical
Things
(IoMT),
(IoT)
is
integrated
with
medical
devices,
enabling
improved
patient
comfort,
cost-effective
solutions,
quick
hospital
treatments,
and
even
more
personalized
healthcare.
The
paper
first
provides
introduction
IoMTs
then
introduces
an
architecture
IoMTs.
Later,
it
current
operations
healthcare
system
discusses
mapping
these
into
architectural
diagram.
Further,
several
emerging
technologies
such
as
Physically
Unclonable
Functions
(PUF),
Blockchain,
Artificial
Intelligence
(AI),
Software-Defined
Networking
(SDN)
are
envisioned
important
to
overcome
challenges
in
e-healthcare
security,
privacy,
accuracy,
performance.
Finally,
we
provide
three
case
studies
for
IoMT
based
on
–
(1)
PUF-based
Authentication,
(2)
AI-enabled
SDN
Assisted
e-healthcare,
(3)
Blockchain
Patient
Centric
System.
solutions
presented
this
may
have
a
huge
impact
speed
at
which
infrastructure
can
efficiently
evolve
market
evolution.
International Journal of Molecular Sciences,
Journal Year:
2021,
Volume and Issue:
22(4), P. 1676 - 1676
Published: Feb. 7, 2021
De
novo
drug
design
is
a
computational
approach
that
generates
novel
molecular
structures
from
atomic
building
blocks
with
no
priori
relationships.
Conventional
methods
include
structure-based
and
ligand-based
design,
which
depend
on
the
properties
of
active
site
biological
target
or
its
known
binders,
respectively.
Artificial
intelligence,
including
ma-chine
learning,
an
emerging
field
has
positively
impacted
discovery
process.
Deep
reinforcement
learning
subdivision
machine
combines
artificial
neural
networks
reinforcement-learning
architectures.
This
method
successfully
been
em-ployed
to
develop
de
approaches
using
variety
recurrent
networks,
convolutional
generative
adversarial
autoencoders.
review
article
summarizes
advances
in
conventional
growth
algorithms
advanced
machine-learning
methodologies
high-lights
hot
topics
for
further
development.
Data Science and Management,
Journal Year:
2021,
Volume and Issue:
4, P. 19 - 29
Published: Dec. 1, 2021
The
field
of
machine
learning
(ML)
is
sufficiently
young
that
it
still
expanding
at
an
accelerating
pace,
lying
the
crossroads
computer
science
and
statistics,
core
artificial
intelligence
(AI)
data
science.
Recent
progress
in
ML
has
been
driven
both
by
development
new
algorithms
theory,
ongoing
explosion
availability
vast
amount
(often
referred
to
as
"big
data")
low-cost
computation.
adoption
ML-based
approaches
can
be
found
throughout
science,
technology
industry,
leading
more
evidence-based
decision-making
across
many
walks
life,
including
healthcare,
biomedicine,
manufacturing,
education,
financial
modeling,
governance,
policing,
marketing.
Although
past
decade
witnessed
increasing
interest
these
fields,
we
are
just
beginning
tap
potential
for
studying
systems
improve
with
experience.
In
this
paper,
present
a
comprehensive
view
on
geo
worldwide
trends
(taking
into
account
China,
USA,
Israel,
Italy,
UK,
Middle
East)
highlighting
rapid
growth
last
5
years
attributable
introduction
related
national
policies.
Furthermore,
based
literature
review,
also
discuss
research
directions
field,
summarizing
some
popular
application
areas
technology,
such
cyber-security
systems,
sustainable
agriculture,
nanotechnology,
suggest
"dissemination
research"
scientific
community
undergone
exceptional
time
range
2018–2020,
reaching
value
16,339
publications.
Finally,
report
challenges
regulatory
standpoints
managing
technology.
Overall,
hope
work
will
help
explain
their
applicability
various
real-world
domains,
well
serve
reference
point
academia
industry
professionals,
particularly
from
technical,
ethical
view.
In
the
current
age
of
Fourth
Industrial
Revolution
($4IR$
or
Industry
$4.0$),
digital
world
has
a
wealth
data,
such
as
Internet
Things
(IoT)
cybersecurity
mobile
business
social
media
health
etc.
To
intelligently
analyze
these
data
and
develop
corresponding
real-world
applications,
knowledge
artificial
intelligence
(AI),
particularly,
machine
learning
(ML)
is
key.
Various
types
algorithms
supervised,
unsupervised,
semi-supervised,
reinforcement
exist
in
area.
Besides,
deep
learning,
which
part
broader
family
methods,
can
on
large
scale.
this
paper,
we
present
comprehensive
view
that
be
applied
to
enhance
capabilities
an
application.
Thus,
study's
key
contribution
explaining
principles
different
techniques
their
applicability
various
applications
areas,
cybersecurity,
smart
cities,
healthcare,
business,
agriculture,
many
more.
We
also
highlight
challenges
potential
research
directions
based
our
study.
Overall,
paper
aims
serve
reference
point
for
not
only
application
developers
but
decision-makers
researchers
particularly
from
technical
view.
Journal of Industrial Integration and Management,
Journal Year:
2020,
Volume and Issue:
05(04), P. 507 - 530
Published: Oct. 1, 2020
Industry
5.0,
the
fifth
industrial
revolution,
consists
of
smart
digital
information
and
manufacturing
technologies.
This
revolution
generates
effective
processes
makes
rapid
improvement
in
industries
healthcare.
Solutions
to
challenges
posed
by
COVID-19
pandemic
can
be
identified
with
deployment
5.0-based
It
helps
provide
personalized
therapy
treatment
patients
if
a
detailed
patient’s
is
available.
The
aim
5.0
technologies
create
healthcare
environment
real-time
capabilities.
During
pandemic,
these
remote
monitoring
system
paper
identifies
studies
major
helpful
for
pandemic.
supportive
features
are
discussed
diagrammatically.
Finally,
we
studied
significant
faced
context
literature
revealed
that
this
technological
innovation
allows
high
personalization
level
fulfill
personal
specific
demands
patient
doctors.
These
play
role
making
life
doctors
better.
Further,
use
technology
focus
on
critically
infected
proper
appropriate
regarding
their
better
treatment.
Moreover,
help
medical
students
required
training
during
outbreak.