Ecotoxicology and Environmental Safety,
Journal Year:
2023,
Volume and Issue:
267, P. 115645 - 115645
Published: Nov. 1, 2023
The
increased
awareness
about
possible
health
effects
arising
from
micro-
and
nanoplastics
(MNPs)
pollution
is
driving
a
huge
amount
of
studies.
Many
international
efforts
are
in
place
to
better
understand
characterize
the
hazard
MNPs
present
environment.
literature
search
was
performed
according
Preferred
Reporting
Items
for
Systematic
Reviews
Meta-Analyses
(PRISMA)
methodology
two
different
databases
(PubMed
Embase).
selection
articles
carried
out
blind,
screening
titles
abstracts
inclusion
exclusion
criteria.
In
general,
these
studies
rely
on
already
use
assessing
nanomaterials
particles
concern.
However,
only
limited
number
have
so
far
directly
measured
human
exposure
examined
relationship
between
such
its
impact
health.
This
review
aims
provide
an
overview
current
state
research
biomarkers
oxidative
stress,
inflammation,
genotoxicity
that
been
explored
relation
exposure,
using
human,
cellular,
animal,
plant
models.
Both
in-vitro
in-vivo
models
suggest
level
stress
inflammation
as
main
mechanism
action
(MOA)
leading
adverse
chronic
immunotoxicity
genotoxicity.
With
identification
biological
endpoints,
representing
critical
key
initiating
events
(KIEs)
towards
adaptive
or
outcomes,
it
identify
panel
surrogate
be
applied
validated
especially
occupational
settings,
where
higher
levels
may
occur.
Critical Reviews in Food Science and Nutrition,
Journal Year:
2022,
Volume and Issue:
64(11), P. 3502 - 3521
Published: Oct. 17, 2022
Plastic
waste
pollution
is
one
of
the
biggest
problems
in
world
today.
The
amount
plastic
environment
continues
to
increase,
and
human
exposure
microplastic
(MP)
has
become
a
reality.
This
subject
attracted
attention
whole
world.
MP
problem
also
been
noticed
by
scientific
community.
term
mostly
used
define
synthetic
material
with
high
polymer
content
that
can
have
size
range
from
0.1
5000
µm.
paper
aims
characterize
routes
MP,
its
sources,
identify
food
types
contaminated
plastics.
review
addresses
current
state
knowledge
on
this
type
particles,
particular
emphasis
their
influence
health.
Adverse
effects
depend
sources
exposure.
most
common
route
believed
be
gastrointestinal
tract.
Sources
include
fish,
shellfish,
water
as
well
tea,
beer,
wine,
energy
drinks,
soft
milk,
salt,
sugar,
honey,
poultry
meat,
fruits,
vegetables.
Studies
shown
particles
PET,
PE,
PP,
PS,
PVC,
PA,
PC
are
frequently
found
food.
Materials,
Journal Year:
2023,
Volume and Issue:
16(2), P. 674 - 674
Published: Jan. 10, 2023
Plastics
are
commonly
used
for
packaging
in
the
food
industry.
The
most
popular
thermoplastic
materials
that
have
found
such
applications
polyethylene
(PE),
polypropylene
(PP),
poly(ethylene
terephthalate)
(PET),
and
polystyrene
(PS).
Unfortunately,
plastic
is
disposable.
As
a
consequence,
significant
amounts
of
waste
generated,
entering
environment,
undergoing
degradation
processes.
They
can
occur
under
influence
mechanical
forces,
temperature,
light,
chemical,
biological
factors.
These
factors
present
synergistic
or
antagonistic
effects.
result
their
action,
microplastics
formed,
which
undergo
further
fragmentation
decomposition
into
small-molecule
compounds.
During
process,
various
additives
at
plastics'
processing
stage
also
be
released.
Both
negatively
affect
human
animal
health.
Determination
negative
consequences
on
environment
health
not
possible
without
knowing
course
processes
products.
In
this
article,
we
sources
microplastics,
causes
places
formation,
transport
particles,
plastics
often
production
storage,
affecting
said
its
Environmental Science & Technology,
Journal Year:
2023,
Volume and Issue:
57(7), P. 2804 - 2812
Published: Feb. 7, 2023
Nanoplastics
(NPs,
<1
μm)
are
of
great
concern
worldwide
because
their
high
potential
risk
toward
organisms
in
aquatic
systems,
while
very
little
work
has
been
focused
on
tissue-specific
toxicokinetics
due
to
the
limitations
NP
quantification
for
such
a
purpose.
In
this
study,
NPs
with
two
different
sizes
(86
and
185
nm)
were
doped
palladium
(Pd)
accurately
determine
uptake
depuration
kinetics
various
tissues
(intestine,
stomach,
liver,
gill,
muscle)
tilapia
(Oreochromis
niloticus)
water,
subsequently,
corresponding
toxic
effects
intestine
explored.
Our
results
revealed
constants
2.70-378
L
kg-1
day-1
0.138-0.407
first
time,
found
be
highly
dependent
particle
size.
The
exhibited
greatest
relative
accumulation
both
NPs;
smaller
caused
more
severe
damage
than
larger
intestinal
mucosal
layer,
induced
greater
impact
microbiota
composition.
findings
explicitly
indicate
size-dependent
toxicity
pathways
NPs,
providing
new
insights
into
ecological
organisms.
Antioxidants,
Journal Year:
2024,
Volume and Issue:
13(5), P. 579 - 579
Published: May 8, 2024
Microplastics
(MPs)
are
plastic
particles
between
0.1
and
5000
µm
in
size
that
have
attracted
considerable
attention
from
the
scientific
community
general
public,
as
they
threaten
environment.
contribute
to
various
harmful
effects,
including
lipid
peroxidation,
DNA
damage,
activation
of
mitogen-activated
protein
kinase
pathways,
cell
membrane
breakages,
mitochondrial
dysfunction,
lysosomal
defects,
inflammation,
apoptosis.
They
affect
cells,
tissues,
organs,
overall
health,
potentially
contributing
conditions
like
cancer
cardiovascular
disease.
pose
a
significant
danger
due
their
widespread
occurrence
food.
In
recent
years,
information
has
emerged
indicating
MPs
can
cause
oxidative
stress
(OS),
known
factor
accelerating
aging
organisms.
This
comprehensive
evaluation
exposed
notable
variability
reported
connection
OS.
work
aims
provide
critical
review
whether
harmfulness
constitute
environmental
contaminants
may
result
OS
through
analysis
research
existing
literature,
well
an
assessment
characteristics
causing
Additionally,
article
covers
analytical
methodology
used
this
field.
The
conclusions
point
necessity
for
further
into
effects
on
Current Research in Biotechnology,
Journal Year:
2024,
Volume and Issue:
7, P. 100190 - 100190
Published: Jan. 1, 2024
Chemically,
microplastics
(MPs)
are
synthetic
materials
composed
of
plastic
monomers
and
additives
vary
in
size
from
0.1
to
5000
μm.
Due
their
chemical
stability
the
widespread
use
plastics
for
various
purposes,
MP
contamination
environment
has
increased
dramatically,
leading
daily
consumer
products
as
well.
Although
previous
studies
have
reported
environmental
impacts
MPs,
only
a
few
highlighted
occurrence
MPs
food
possible
effects
on
human
health.
Recent
investigations
identified
particles
drinking
water
other
beverages,
seafood,
plant
products,
salt,
sugar,
honey,
raising
an
alarm
over
safety
quality
these
items.
Ingestion,
inhalation,
dermal
contact
such
goods
common
routes
through
which
may
enter
body
can
several
deleterious
health
including
oxidative
stress,
inflammation,
immunotoxicity,
risk
neoplasia,
cellular
metabolism
impairment,
neurotoxicity,
gut
microbiome
dysbiosis,
disruption
reproductive
system
among
others.
A
collective
approach
employing
source
control,
recycling,
biodegradable
plastics,
strengthening
legislation,
bioremediation
could
be
promising
sustainable
solution
control
pollution.
The
key
challenge
appears
standarize
detection
methods
along
with
reducing
well
environment.
Therefore,
this
review
focuses
current
analysis,
potential
impacts,
strategies
mitigate
It
also
adds
novel
findings,
knowledge
gaps,
recommendations
that
guide
future
research
field.
