EU Expert Bodies in Light of the Glyphosate Saga and the Dieselgate Scandal DOI Open Access
László Szegedi

Európai Tükör, Journal Year: 2022, Volume and Issue: 25(3-4), P. 93 - 116

Published: Jan. 1, 2022

Several scandals shed light on the eroding capacity and legitimacy of Single Market’s scientific decision-making in current era constant economic, environmental societal challenges when need for solid science has never been greater. A sector-specific nature still characterises EU law Market competencies. Yet, emerging relevance law’s horizontal evolution inevitably leads us to cross-sectoral elements expert bodies decision-making. The purposes this paper are 1. describe with comparison two relatively diverse policy areas EU’s food sector transportation, which similarly characterised by glyphosate saga Dieselgate scandal; 2. explore these

Language: Английский

Dual-recognition “turn-off-on” fluorescent Biosensor triphenylamine-based continuous detection of copper ion and glyphosate applicated in environment and living system DOI

Ya-Tong Liu,

Qianqian Zhang,

Si-Yi Yao

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 477, P. 135216 - 135216

Published: July 23, 2024

Language: Английский

Citations

15

IARC Workshop on the Key Characteristics of Carcinogens: Assessment of End Points for Evaluating Mechanistic Evidence of Carcinogenic Hazards DOI Creative Commons
David M. DeMarini,

William M. Gwinn,

Emily Watkins

et al.

Environmental Health Perspectives, Journal Year: 2025, Volume and Issue: 133(2)

Published: Feb. 1, 2025

The 10 key characteristics (KCs) of carcinogens form the basis a framework to identify, organize, and evaluate mechanistic evidence relevant carcinogenic hazard identification. KCs are related mechanisms by which cause cancer. International Agency for Research on Cancer (IARC) Monographs programme has successfully applied evaluation different types exposures, including chemicals, metals, complex such as environmental, occupational, or dietary exposures. use this significantly enhanced identification organization data, minimized bias in evaluations, enriched knowledge base regarding known suspected carcinogens. We sought report main outcomes an IARC Scientific Workshop convened establish appropriate, transparent, uniform application future evaluations. A group experts from disciplines reviewed experience with carcinogens, discussing three themes: a) interpretation end points forming KCs, b) incorporation data novel assays c) integration part cancer workshop participants assessed relevance informativeness multiple KCs-associated studies exposed humans experimental systems. Consensus was reached how enhance silico, molecular, cellular high-output high-throughput data. In addition, approaches integrate across opportunities improve methodologies hazards were explored. findings described herein forthcoming technical will support working groups reporting interpreting results under within other contexts. https://doi.org/10.1289/EHP15389.

Language: Английский

Citations

1

Ecotoxicological mechanism of glyphosate on Moerella iridescens: Evidence from enzyme, histology and metabolome DOI
Yuhan Jiang, Yuhang He, Ruilin Pei

et al.

Marine Pollution Bulletin, Journal Year: 2025, Volume and Issue: 213, P. 117680 - 117680

Published: Feb. 17, 2025

Language: Английский

Citations

1

Quantum Simulations and Experimental Insights into Glyphosate Adsorption Using Graphene-Based Nanomaterials DOI
Wanderson Souza Araújo, Celso R. C. Rêgo, Diego Guedes‐Sobrinho

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(24), P. 31500 - 31512

Published: June 6, 2024

The increasing global demand for food and agrarian development brings to light a dual issue concerning the use of substances that are crucial productivity yet can be harmful human health environment when misused. Herein, we combine insights from high-level quantum simulations experimental findings elucidate fundamental physicochemical mechanisms behind developing graphene-based nanomaterials adsorption emerging contaminants, with specific focus on pesticide glyphosate (GLY). We conducted comprehensive theoretical investigation supports as promising candidates detecting, sensing, capturing, removing GLY applications. By combining ab initio molecular dynamics density functional theory calculations, explored several chemical environments encountered by during its interaction substrates, including pristine punctual defect regions. Our results unveiled distinct behaviors: physisorption in doped graphene regions, chemisorption leading dissociation vacancy-type complex transformations involving capture N O atoms impurity-adsorbed graphene, resulting formation new GLY-derived compounds. were substantiated FTIR Raman spectroscopy, which proposed mechanism explaining nanomaterials. evaluation energies associated properties provides valuable into intricate nature these interactions, shedding potential applications guiding future investigations nanofilters water decontamination.

Language: Английский

Citations

5

Two swords combination: Smartphone-assisted ratiometric fluorescent and paper sensors for dual-mode detection of glyphosate in edible malt DOI
Kai Deng,

Haipeng Guo,

Xueying Li

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 454, P. 139744 - 139744

Published: May 20, 2024

Language: Английский

Citations

4

Detection of glyphosate, glufosinate, and their metabolites in multi-floral honey for food safety DOI
Giulia Rampazzo, Maria Nobile, Stefania Carpino

et al.

Food Additives & Contaminants Part A, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 10

Published: Jan. 10, 2025

Beehives can accumulate environmental contaminants as bees gather pollen, propolis, and water from their surroundings, contaminating hive products like honey. Moreover, in multifloral environments, interact with plants treated different pesticides, often causing higher pesticides concentrations multi-floral honey than mono-floral varieties. Glyphosate glufosinate are both widely used herbicides. accounted for one-third of herbicide sales Europe 2017 continues to raise health concerns, including its potential carcinogenicity. While the European Commission extended glyphosate's authorisation another 10 years 2023, concerns remain about impact on biodiversity human health. This study aimed monitor presence glyphosate, glufosinate, metabolites 100 samples representing Italian production by analysis using IC-HRMS. Results indicated that 12% contained glyphosate residues ranging > LOQ 45 ng g

Language: Английский

Citations

0

Hypothesis: glyphosate-based herbicides can increase risk of hematopoietic malignancies through extended persistence in bone DOI Creative Commons
Charles Benbrook

Environmental Sciences Europe, Journal Year: 2025, Volume and Issue: 37(1)

Published: Jan. 29, 2025

Language: Английский

Citations

0

Glyphosate-based herbicide as a potential risk factor for breast cancer DOI
Lyvia Neves Rebello Alves,

Luiza Poppe Merigueti,

Matheus Correia Casotti

et al.

Food and Chemical Toxicology, Journal Year: 2025, Volume and Issue: unknown, P. 115404 - 115404

Published: March 1, 2025

Language: Английский

Citations

0

Toxicological concerns regarding glyphosate, its formulations, and co-formulants as environmental pollutants: a review of published studies from 2010 to 2025 DOI Creative Commons
Szandra Klátyik, G. Simon, Eszter Takács

et al.

Archives of Toxicology, Journal Year: 2025, Volume and Issue: unknown

Published: May 26, 2025

Language: Английский

Citations

0

Urinary glyphosate levels and association with mortality in the 2013–16 National Health and Nutrition Examination Survey DOI
Matthew Untalan,

Tara Ivic‐Pavlicic,

Emanuela Taioli

et al.

Carcinogenesis, Journal Year: 2023, Volume and Issue: 45(3), P. 163 - 169

Published: Dec. 2, 2023

Abstract Objectives Glyphosate is the most commonly used herbicide in USA; however, its safety still under debate. We assessed glyphosate levels and their association with overall mortality a representative sample of US adult population from 2013 to 2016 National Health Nutrition Examination Survey. Methods extracted data on urinary (N = 2910) measured by ion chromatography isotope-dilution tandem mass spectrometry. Associations between concentrations demographic, lifestyle other exposures were analyzed. Data linked public-use Mortality Files for 2019. Results The mean (STD) level was 0.53 (0.59) ng/ml, 25.7% subjects having at or below detection limit. At multivariate analysis, age creatinine associated (both P < 0.0001). There borderline (HRadj 1.33; 95% CI 0.99–1.77 0.06). When 3,5,6-trichloropyridinol excluded Cox model, exhibits significant 1.00–1.77; 0.0532). Conclusions These nationally suggest that recent exposure could be increased mortality. More studies are necessary understand population-level risk product, given widespread use agriculture.

Language: Английский

Citations

6