Rice Straw-Derived Biochar Mitigates Microcystin-LR-Induced Hepatic Histopathological Injury and Oxidative Damage in Male Zebrafish via the Nrf2 Signaling Pathway DOI Creative Commons
Wang Lin, Fen Hu,

Wansheng Zou

et al.

Toxins, Journal Year: 2024, Volume and Issue: 16(12), P. 549 - 549

Published: Dec. 18, 2024

Microcystin-leucine arginine (MC-LR) poses a serious threat to aquatic animals during cyanobacterial blooms. Recently, biochar (BC), derived from rice straw, has emerged as potent adsorbent for eliminating hazardous contaminants water. To assess the joint hepatotoxic effects of environmentally relevant concentrations MC-LR and BC on fish, male adult zebrafish (Danio rerio) were sub-chronically co-exposed varying (0, 1, 5, 25 μg/L) (0 100 in fully factorial experiment. After 30 days exposure, our findings suggested that existence significantly decreased bioavailability liver. Furthermore, histopathological analysis revealed mitigated MC-LR-induced hepatic lesions, which characterized by mild damage, such vacuolization, pyknotic nuclei, swollen mitochondria. Compared groups exposed solely MC-LR, malondialdehyde (MDA) increased catalase (CAT) superoxide dismutase (SOD) noticed mixture groups. Concurrently, significant changes mRNA expression levels Nrf2 pathway genes (cat, sod1, gstr, keap1a, nrf2a, gclc) further proved reduces oxidative damage induced MC-LR. These demonstrate decreases liver, thereby alleviating hepatotoxicity through signaling zebrafish. Our results also imply could serve potentially friendly material mitigating detrimental fish.

Language: Английский

Role of biochar pyrolysis temperature on intracellular and extracellular biodegradation of biochar-adsorbed organic compounds DOI
Jiaqi Tao, Wenhao Wu, Daohui Lin

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 346, P. 123583 - 123583

Published: Feb. 14, 2024

Language: Английский

Citations

6
Joint effects of rice straw-derived biochar and microcystin-LR on splenic histopathological injuries, inflammation, and innate immune responses in male zebrafish DOI
Wang Lin, Ling Liao,

Ling Ling

et al.

Fish & Shellfish Immunology, Journal Year: 2025, Volume and Issue: 162, P. 110370 - 110370

Published: April 25, 2025

Language: Английский

Citations

0
New challenge: Mitigation and control of antibiotic resistant genes in aquatic environments by biochar DOI

Yimeng Feng,

Tong Xie,

Fengxiang Li

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 946, P. 174385 - 174385

Published: July 1, 2024

Language: Английский

Citations

3
Effective application of green nano adsorbent on the removal of carbofuran from wastewater DOI
N. M. Aboeleneen,

Nabil Abdelmonem,

R. Atef

et al.

Chemical Engineering Communications, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 15

Published: Sept. 20, 2024

Language: Английский

Citations

1
Mechanism and toxicity assessment of carbofuran degradation by persulfate-based advanced oxidation process DOI Creative Commons
Chenxi Zhang,

Youxin Xu,

Bingbing Chu

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(42), P. 30582 - 30589

Published: Jan. 1, 2024

The advanced oxidation process based on persulfate has been proven to be a promising method for degrading the highly toxic carbamate pesticide carbofuran (CBF).

Language: Английский

Citations

0
Rice Straw-Derived Biochar Mitigates Microcystin-LR-Induced Hepatic Histopathological Injury and Oxidative Damage in Male Zebrafish via the Nrf2 Signaling Pathway DOI Creative Commons
Wang Lin, Fen Hu,

Wansheng Zou

et al.

Toxins, Journal Year: 2024, Volume and Issue: 16(12), P. 549 - 549

Published: Dec. 18, 2024

Microcystin-leucine arginine (MC-LR) poses a serious threat to aquatic animals during cyanobacterial blooms. Recently, biochar (BC), derived from rice straw, has emerged as potent adsorbent for eliminating hazardous contaminants water. To assess the joint hepatotoxic effects of environmentally relevant concentrations MC-LR and BC on fish, male adult zebrafish (Danio rerio) were sub-chronically co-exposed varying (0, 1, 5, 25 μg/L) (0 100 in fully factorial experiment. After 30 days exposure, our findings suggested that existence significantly decreased bioavailability liver. Furthermore, histopathological analysis revealed mitigated MC-LR-induced hepatic lesions, which characterized by mild damage, such vacuolization, pyknotic nuclei, swollen mitochondria. Compared groups exposed solely MC-LR, malondialdehyde (MDA) increased catalase (CAT) superoxide dismutase (SOD) noticed mixture groups. Concurrently, significant changes mRNA expression levels Nrf2 pathway genes (cat, sod1, gstr, keap1a, nrf2a, gclc) further proved reduces oxidative damage induced MC-LR. These demonstrate decreases liver, thereby alleviating hepatotoxicity through signaling zebrafish. Our results also imply could serve potentially friendly material mitigating detrimental fish.

Language: Английский

Citations

0