Aquatic Toxicology, Journal Year: 2024, Volume and Issue: 279, P. 107224 - 107224
Published: Dec. 28, 2024
Language: Английский
The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 918, P. 170568 - 170568
Published: Feb. 2, 2024
Among personal care products, quaternium-15 is prominently featured as a preservative in items such shampoos, soaps, shaving and cosmetics. The widespread use of these products people's daily routines contributes to release into aquatic ecosystems. In this context, the primary aim study was assess physiological cellular responses digestive gland gills Mytilus galloprovincialis exposure. Cell viability ability cells regulate their volume were evaluated. Additionally, expression genes involved oxidative stress response assessed further substantiate compound's harmful effects. Results indicated significant decrease both RVD (regulatory decrease) capacity when exposed hypotonic solution. Furthermore, impairment cell function corroborated by modulation stress-related gene expression, including SOD, Cat, well Hsp70 CYP4Y1. Similar alterations observed gills, reflecting impaired functionality vital organ well. summary, outcomes provide conclusive evidence toxicity quaternium-15. This underscores urgent need investigate toxicological effects contaminant on ecosystems emphasises necessity limiting containing
Language: Английский
Citations
17
Environmental Pollution, Journal Year: 2024, Volume and Issue: 350, P. 123724 - 123724
Published: March 8, 2024
Language: Английский
Citations
16
Journal of Contaminant Hydrology, Journal Year: 2024, Volume and Issue: 266, P. 104399 - 104399
Published: July 17, 2024
Improper disposal of household and industrial waste into water bodies has transformed them de facto dumping grounds. Plastic debris, weathered on beaches degrades micro-particles releases chemical additives that enter the water. Microplastic contamination is documented globally in both marine freshwater environments, posing a significant threat to aquatic ecosystems. The small size these particles makes susceptible ingestion by low trophic fauna, trend expected escalate. Ingestion leads adverse effects like intestinal blockages, alterations lipid metabolism, histopathological changes intestine, contributing extinction vulnerable species disrupting ecosystem balance. Notably, microplastics (MPs) can act as carriers for pathogens, potentially causing impaired reproductive activity, decreased immunity, cancer various organisms. Studies have identified seven principal sources MPs, including synthetic textiles (35%) tire abrasion (28%), highlighting human contribution this pollution. This review covers aspects microplastic pollution, sources, extraction methods, its profound impact Additionally, it explores preventive measures, aiming guide researchers selecting techniques inspiring further investigation far-reaching impacts fostering effective solutions environmental challenge.
Language: Английский
Citations
13
The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 946, P. 173809 - 173809
Published: June 5, 2024
Drugs are chemical compounds used to treat and improve organic dysfunctions caused by diseases. These include analgesics, antibiotics, antidepressants, antineoplastics. They can enter aquatic environments through wastewater streams, where their physico-chemical properties allow metabolites distribute accumulate. Current climate change associated extreme weather events may significantly impact these substances' toxicity organisms' sensitivity. Among the chemicals present in is non-steroidal anti-inflammatory drug diclofenac (DIC), which EU monitors due its concentration levels. This study investigated influence of temperature (control at 17 °C vs. 21 °C) on effects DIC (0 μg/L 1 μg/L) mussel species Mytilus galloprovincialis. Significant results were observed between °C. Organisms exposed higher showed a decrease several parameters, including metabolic capacity detoxification, particularly with prolonged exposure. However, some after days, M. galloprovincialis no differences from control, indicating adaptation stress. The this confirm that concentrations environment, when combined increased temperatures, produce oxidative stress adversely affect biochemical physiological performance. also validates as bioindicator for assessing environmental contamination DIC. Beyond direct organisms, presence pharmaceuticals like environment highlights interconnectedness human, animal, ecosystem health, underscoring One Health approach understanding mitigating pollution.
Language: Английский
Citations
7
Aquatic Toxicology, Journal Year: 2024, Volume and Issue: 273, P. 107014 - 107014
Published: June 27, 2024
In the last decades, pharmaceuticals have emerged as a new class of environmental contaminants. Antihypertensives, including angiotensin-converting enzyme (ACE) inhibitors, are special concern due to their increased consumption over past years. However, available data on putative effects health aquatic animals, well possible interaction with biological systems still poorly understood. This study analysed whether and which extent exposure Enalapril, an ACE inhibitor commonly used for treating hypertension heart failure, may induce morpho-functional alterations in mussel Mytilus galloprovincialis, sentinel organism water pollution. By mainly focusing digestive gland (DG), target tissue analysing xenobiotics mussels, 10-days 0.6 ng/L (E1) 600 (E2) Enalapril were investigated terms cell viability volume regulation, morphology, oxidative stress, stress protein expression localization. Results indicated that compromised capacity DG cells from E2 group regulate by limiting ability return original after hypoosmotic stress. occurred without significant viability. unaffected also haemocytes viability, although infiltration was histologically observed both groups, suggestive immune response. No changes two experimental groups localization heat shock proteins 70 (HSPs70) HSP90, levels biomarkers. Our results showed that, M. galloprovincialis did not influence status, stress-related proteins, while it activated response face osmotic changes, potential consequences animal performance.
Language: Английский
Citations
5
Environmental Pollution, Journal Year: 2025, Volume and Issue: 371, P. 125939 - 125939
Published: Feb. 27, 2025
Language: Английский
Citations
0
Current Issues in Molecular Biology, Journal Year: 2025, Volume and Issue: 47(3), P. 175 - 175
Published: March 7, 2025
Marine-derived biomaterials are emerging as promising candidates for tissue regeneration due to their sustainability, biocompatibility, bioactivity, and unique chemical structure. This review provides an overview of different marine-derived inorganic organic materials, such calcium carbonate, magnesium salts, silica, polysaccharides, bioactive peptides, lipid-based compounds, effects in promoting osteogenesis. Specifically, the osteoinductive, osteoconductive, osteointegrative activities traditional innovative materials that influence key molecular pathways BMP/Smad Wnt/β-catenin signaling underlying bone formation will be evaluated. also prospects approaches, i.e., phage display technology, optimize peptides targeted regeneration. In context sustainable this suggests some interesting applications unusual able overcome limitations conventional ones stimulate cellular by activating specific pathways.
Language: Английский
Citations
0
Microscopy Research and Technique, Journal Year: 2025, Volume and Issue: unknown
Published: March 17, 2025
ABSTRACT This study investigates the effects of polyethylene glycol (PEG) on Mytilus galloprovincialis , a key sentinel species in marine environments. As PEGs are widely used personal care products and pharmaceuticals, their increasing presence ecosystems poses potential threat to non‐target organisms. A total 150 mussels were exposed different concentrations PEG (0.1 mg/L 10 mg/L) over 14 days. The impact exposure was assessed through cell viability assays, regulatory volume decrease (RVD) tests, histological analysis, respectively, hemolymph digestive gland (DG) cells, gills, DG, gonads. Significant reductions observed hemocytes DG particularly at higher concentrations. Histological analysis revealed pronounced tissue damage, including hemocyte infiltration, lipofuscin aggregation, epithelial disorganization hepatopancreas, gonads, indicating PEG‐induced cytotoxicity. also impaired RVD mechanisms highlighting changes regulation. These findings demonstrate that can induce significant physiological morphological alterations mussels, raising concerns about its aquatic ecosystems.
Language: Английский
Citations
0
Environmental Toxicology and Pharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 104682 - 104682
Published: March 1, 2025
Language: Английский
Citations
0
Biochemistry, Journal Year: 2024, Volume and Issue: unknown
Published: July 16, 2024
A measurable and/or observable change in a biological or biochemical reaction, encompassing behavioral alterations as well molecular to physiological levels, is referred biomarker. Biomarker responses must be ecologically meaningful and show exposure the harmful consequences of environmental stressors. When assessing condition an ecosystem, biomarkers are regarded early warning systems. They useful for evaluating in-situ chemical impacts contaminants on biota. Although they assessed individual basis, purpose their reactions forecast population-level consequences. We hope give broad definition xenobiotics this chapter, overview processes involved biotransformation detoxification aquatic organisms.
Language: Английский
Citations
3