Co-exposure to Enrofloxacin and Atrazine Enhances the Hepatotoxicity in Larimichthys crocea by Targeting the Hypothalamic–Pituitary–Thyroid and Gut–Liver Axes

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 489, P. 137548 - 137548

Published: Feb. 10, 2025

Language: Английский

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Co-exposure of TMPs and antibiotics in zebrafish: The influence of additives on the risk of hepatotoxicity

Environmental Research, Journal Year: 2025, Volume and Issue: unknown, P. 121430 - 121430

Published: March 1, 2025

Language: Английский

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Metabolomics Insights into Gut Microbiota and Functional Constipation

Metabolites, Journal Year: 2025, Volume and Issue: 15(4), P. 269 - 269

Published: April 12, 2025

Background: The composition and metabolic activity of the gut microbiota play a crucial role in various health conditions, including occurrence development chronic constipation. Recent metabolomic advances reveal that microbiota-derived metabolites—such as SCFAs, bile acids, neurotransmitters, microbial gases—play critical roles regulating intestinal function. Methods: We systematically analyzed current literature on metabolomics This review consolidates findings from high-throughput techniques (GC-MS, LC-MS, NMR) comparing profiles constipated patients with healthy individuals. It also examines diagnostic improvements personalized treatments, fecal transplantation neuromodulation, guided by these insights. Results: shows reduced SCFA levels impair motility promote inflammation. An altered acid metabolism—with decreased secondary acids like deoxycholic acid—disrupts receptor-mediated signaling, further affecting motility. Additionally, imbalances amino metabolism neurotransmitter production contribute to neuromuscular dysfunction, while variations gas (e.g., methane vs. hydrogen) modulate transit. Conclusions: Integrating research clarifies how specific metabolites regulate These insights offer promising directions for precision diagnostics targeted therapies restore balance improve

Language: Английский

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Integrated plant physiology, transcriptomics, and metabolomics reveal tobacco root growth and nicotine synthesis responses in tobacco exposure to different nitrogen forms

Chemical and Biological Technologies in Agriculture, Journal Year: 2025, Volume and Issue: 12(1)

Published: March 21, 2025

Language: Английский

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Toxic effects of emerging pollutants on mucosal organs of teleost fish: A review focusing on mucosal microbiota, physical barrier and immune barrier

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 978, P. 179431 - 179431

Published: April 16, 2025

Language: Английский

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A nationwide probabilistic risk assessment and a new insight into source-specific risk apportionment of antibiotics in eight typical river basins in China: Human health risk and ecological risk

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 484, P. 136674 - 136674

Published: Nov. 28, 2024

Language: Английский

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Proton Conductive 2D MXene-derived Potassium Titanate Nanoribbons Fabricated Electrochemical Platform for Trace Detection of Enrofloxacin

Chemosphere, Journal Year: 2024, Volume and Issue: 366, P. 143520 - 143520

Published: Oct. 1, 2024

Language: Английский

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Behavioral dysregulation in Nile tilapia (Oreochromis niloticus, GIFT) post-Streptococcus agalactia infection: Role of the microbiota-gut-brain axis

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Journal Year: 2024, Volume and Issue: 285, P. 110006 - 110006

Published: Aug. 16, 2024

Language: Английский

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Sustainable aquaculture and seafood production using microalgal technology - a circular bioeconomy perspective

Chemosphere, Journal Year: 2024, Volume and Issue: 366, P. 143502 - 143502

Published: Oct. 1, 2024

Language: Английский

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