Journal of drug targeting,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 12
Published: Dec. 21, 2024
Treating
burn
lesions
has
always
been
challenging
because
any
product
should
be
cheap,
accessible,
and
have
anti-bacterial
commodities
tissue
regeneration
properties.
The
green
synthesis
of
magnesium
oxide
nanoparticles
(GS-MgONPs)
can
create
an
optimal
prospect
that
is
safe
with
low
toxicity
in
biological
better
safety
for
application
while
including
the
antibacterial
effect.
This
recent
study
aimed
to
evaluate
effectiveness
wound
treatment
using
GS-MgONPs
rats.
were
synthesised
first
time
a
Falcaria
vulgaris
extract
(FVE)
characterised.
Thirty
male
Wistar
rats
divided
into
five
groups:
An
untreated
group,
conventional
treated
(1
wt%),
(3
wt%)
5.
FVE
wt%).
Treatments
commenced
immediately
following
induction
administered
daily
duration
21
d.
showed
spherical
morphology
diameter
less
than
100
nm.
NPs
(1%
3
demonstrated
significant
growth
inhibition
against
Staphylococcus
aureus
showing
no
cytotoxic
effects
on
human
fibroblast
cells.
proposed
subjects
1
wt%
able
significantly
increase
rate
closure
(p
<
0.05).
Histological
observations
revealed
collagen
formation
epithelial
more
pronounced
groups
receiving
MgONPs.
These
results
indicate
effectively
enhance
process.
