Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 20, 2024
Abstract
Pathogenic
bacteria
are
commonly
found
in
food,
water,
and
soil,
posing
significant
public
health
challenges
globally.
Therefore,
early,
rapid,
highly
sensitive
strategies
for
monitoring
the
bacterial
proliferation
crucial
ensuring
health,
medical
diagnosis,
food
safety.
Compared
to
traditional
techniques,
microfluidic
platforms
provide
powerful
detective
tools
characterized
by
high
integration,
throughput,
ease
of
operation,
low
reagent
consumption,
sensitivity.
Driven
substantial
commercial
demand,
research
development
microfluidic‐based
rapid
detection
methods
technologies
has
progressed
significantly
derived
interdisciplinary
integration
multiple
disciplines.
In
this
review,
progress
clinical
pathogenic
with
biosensors,
including
devices
point‐of‐care
(POC)
testing,
is
summarized.
Strategies
detection,
containing
their
advantages
disadvantages
discussed
detail.
Advanced
capturing
detecting
bacteria,
such
as
microchannels,
microarrays,
digital
microfluidics
(DMF)
paper‐based
platforms,
highlighted.
The
accomplishments
shortcomings
these
also
Additionally,
case
studies
biosensor‑based
used
diseases
caused
imbalances
listed.
Finally,
possible
perspectives
further
effective
proposed.
European Respiratory Review,
Journal Year:
2024,
Volume and Issue:
33(173), P. 240096 - 240096
Published: July 1, 2024
Recent
bronchiectasis
studies
from
large-scale
multinational,
multicentre
registries
have
demonstrated
that
the
characteristics
of
disease
vary
according
to
geographic
region.
However,
most
perspectives
on
are
dominated
by
data
Western
countries.
This
review
intends
provide
an
Asian
perspective
disease,
focusing
established
in
India,
Korea
and
China.
patients
with
less
likely
show
female
predominance
experience
exacerbations,
more
be
younger,
milder
fewer
options
for
guideline-recommended
treatment
than
those
living
other
global
regions.
Furthermore,
demonstrate
different
comorbidities,
microbiological
profiles
unique
endophenotypes,
including
post-tuberculosis
dry
bronchiectasis.
Notably,
each
region
reveals
further
variations
inter-patient
differences.
Future
warranted
better
characterise
Computational and Structural Biotechnology Journal,
Journal Year:
2023,
Volume and Issue:
21, P. 4933 - 4943
Published: Jan. 1, 2023
The
study
of
the
respiratory
microbiome
has
entered
a
multi-omic
era.
Through
integrating
different
omic
data
types
such
as
metagenome,
metatranscriptome,
metaproteome,
metabolome,
culturome
and
radiome
surveyed
from
specimens,
holistic
insights
can
be
gained
on
lung
its
interaction
with
host
immunity
inflammation
in
diseases.
power
multi-omics
have
moved
field
forward
associative
assessment
alterations
to
causative
understanding
pathogenesis
chronic,
acute
other
However,
application
remains
unique
challenges
sample
processing,
integration,
downstream
validation.
In
this
review,
we
first
introduce
applicable
studying
microbiome.
We
next
describe
approaches
for
focusing
dimensionality
reduction,
association
prediction.
then
summarize
progresses
finally
discuss
current
share
our
thoughts
future
promises
field.
European Respiratory Journal,
Journal Year:
2024,
Volume and Issue:
63(2), P. 2302281 - 2302281
Published: Feb. 1, 2024
Tweetable
abstract
Descriptive
lung
microbiome
studies
are
not
sufficient
to
contribute
clinical
understanding.
Research
now
requires
systematic
exploration
identify
the
contribution
of
non-classical
bacteria
chronic
disease.https://bit.ly/3UbgVCs
Current Opinion in Pulmonary Medicine,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 4, 2024
Purpose
of
review
Advances
in
DNA
sequencing
and
analysis
the
respiratory
microbiome
highlight
its
close
association
with
bronchiectasis
phenotypes,
revealing
fresh
opportunities
for
diagnosis,
stratification,
personalized
clinical
intervention.
An
under-recognized
condition,
is
increasingly
subject
recent
large-scale,
multicentre,
longitudinal
studies
including
detailed
microbiome.
In
this
review,
we
summarize
progress
our
understanding
within
context
potential
use
treatment
decisions.
Recent
findings
Diverse
profiles
exist
bronchiectasis,
line
established
disease
heterogeneity
response.
Classical
microbiology
has
Pseudomonas
aeruginosa
Haemophilus
influenza
as
two
microbial
markers
disease,
while
holistic
uncovered
important
associations
less
common
bacterial
taxa
commensal
an/or
pathobiont
species,
emerging
role
fungal
mycobiome,
virome,
interactome.
Integration
airway
microbiomes
other
high-dimensional
biological
datasets
holds
significant
promise
to
determining
treatable
traits
mechanisms
related
Summary
The
an
key
area
study
implications
influencing
decisions
ultimately
improving
patient
outcomes.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 20, 2024
Abstract
Pathogenic
bacteria
are
commonly
found
in
food,
water,
and
soil,
posing
significant
public
health
challenges
globally.
Therefore,
early,
rapid,
highly
sensitive
strategies
for
monitoring
the
bacterial
proliferation
crucial
ensuring
health,
medical
diagnosis,
food
safety.
Compared
to
traditional
techniques,
microfluidic
platforms
provide
powerful
detective
tools
characterized
by
high
integration,
throughput,
ease
of
operation,
low
reagent
consumption,
sensitivity.
Driven
substantial
commercial
demand,
research
development
microfluidic‐based
rapid
detection
methods
technologies
has
progressed
significantly
derived
interdisciplinary
integration
multiple
disciplines.
In
this
review,
progress
clinical
pathogenic
with
biosensors,
including
devices
point‐of‐care
(POC)
testing,
is
summarized.
Strategies
detection,
containing
their
advantages
disadvantages
discussed
detail.
Advanced
capturing
detecting
bacteria,
such
as
microchannels,
microarrays,
digital
microfluidics
(DMF)
paper‐based
platforms,
highlighted.
The
accomplishments
shortcomings
these
also
Additionally,
case
studies
biosensor‑based
used
diseases
caused
imbalances
listed.
Finally,
possible
perspectives
further
effective
proposed.
