Modern Designs of Electrochemical Sensor for Accurate Drug Analysis in Pharmaceutical and Biological Samples: Principles, Nanofabrication, and Key Challenges

Materials Chemistry and Physics, Journal Year: 2025, Volume and Issue: unknown, P. 130588 - 130588

Published: Feb. 1, 2025

Language: Английский

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Miniaturized green liquid‐phase sample pre‐concentration methods for pharmaceutical drugs assessment in wastewater

Water and Environment Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 27, 2025

Abstract Microextraction methods such as hollow fibre‐liquid phase microextraction (HF‐LPME), dispersive liquid–liquid (DLLME), single‐drop (SDME) and ultrasound‐assisted emulsification (USAEME) have become prominent for analysing pharmaceuticals in wastewater. HF‐LPME, particularly the three‐phase system, excels extracting pollutants with high efficiency. SDME, especially direct immersion (DI) variant, is effective moderately polar non‐polar compounds. DLLME uses an immiscible dispersion extraction solvent to separate analytes, while USAEME enhances using ultrasonic waves. Recent research trends focus on incorporating ionic liquids deep eutectic solvents improve performance. These miniaturized techniques offer selectivity, efficient sample clean‐up significant enrichment factors, making them superior traditional like extraction. Future developments are expected further refine these even better performance pharmaceutical analysis. Complex‐Green Analytical Procedure Index (GAPI) also used assess environmentally friendliness of methodological approaches.

Language: Английский

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Recent developments on nanomaterial probes for detection of pesticide residues: A review

Analytica Chimica Acta, Journal Year: 2022, Volume and Issue: 1215, P. 339974 - 339974

Published: May 25, 2022

Language: Английский

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Analysis types and quantification methods applied in UHPLC-MS metabolomics research: a tutorial

Metabolomics, Journal Year: 2024, Volume and Issue: 20(5)

Published: Aug. 7, 2024

Abstract Background Different types of analytical methods, with different characteristics, are applied in metabolomics and lipidomics research include untargeted, targeted semi-targeted methods. Ultra High Performance Liquid Chromatography-Mass Spectrometry is one the most frequently measurement instruments because its ability to detect a large number water-soluble lipid metabolites over wide range concentrations short analysis times. Methods for detection quantification differ can either report (normalised) peak area or an absolute concentration. Aim review In this tutorial we aim (1) define similarities differences between approaches (2) how amounts endogenous be determined together advantages limitations each approach relation accuracy precision when reported. Key scientific concepts The pre-analysis knowledge targeted, requirement responses reported whether method applied. Fully untargeted methods only provide fold changes which even structural identity metabolite not known. Targeted where analytes known prior analysis, also changes. Semi-targeted apply mix characteristics both assays. For reporting metabolites, predefined but optimized should developed validated analyte so that concentration data collected biological samples as fit purpose reviewed by community.

Language: Английский

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Toward advanced analytical procedures for detecting Fumonisins in contaminated food and feed using molecularly imprinted polymers: A mini review

Microchemical Journal, Journal Year: 2024, Volume and Issue: 207, P. 111858 - 111858

Published: Oct. 10, 2024

Language: Английский

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Sensitive quantification of acetochlor and metolachlor in water using Taguchi-optimized DLLME coupled with high-performance liquid chromatography

Microchemical Journal, Journal Year: 2024, Volume and Issue: 200, P. 110499 - 110499

Published: April 6, 2024

Language: Английский

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Method development, residue level analysis, and dietary risk assessment of six morpholine pesticide residues in plant-derived foods based on modified QuEChERS–liquid chromatography–tandem mass spectrometry

Journal of Food Composition and Analysis, Journal Year: 2024, Volume and Issue: 132, P. 106303 - 106303

Published: May 16, 2024

Language: Английский

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Innovative preparation of ureido/dodecyl dual-functionalized silica as a versatile mixed-mode stationary phase for high-resolution chromatographic separations

Journal of Chromatography A, Journal Year: 2022, Volume and Issue: 1665, P. 462834 - 462834

Published: Jan. 19, 2022

Language: Английский

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Electrochemical detection of dioctyl phthalate using molecularly imprinted polymer modified screen-printed electrodes

Analytica Chimica Acta, Journal Year: 2022, Volume and Issue: 1196, P. 339547 - 339547

Published: Jan. 29, 2022

We report the investigation of electropolymerised molecularly imprinted polymers (E-MIPs) for determination dioctyl phthalate (DOP). Low-cost and eco-friendly commercially available screen-printed electrodes (SPEs) were used. E-MIPs produced using cyclic voltammetry (CV) technique based on a water-soluble 4-aminophenol as functional monomer. DOP showed affinity template, with 80% binding efficiency an imprinting factor 3. The able to detect absolute levels in time-dependent adsorption manner presence 250 μg (equivalent 12.8 μM) detected 5 min LOD (at 15 min) 177.1 LOQ 536.6 making them suitable measurement freshwater when sample is pre-concentrated.

Language: Английский

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Preparation of poly(methacrylic acid-co-ethylene glycol dimethacrylate)-functionalized magnetic polydopamine nanoparticles for the extraction of six cannabinoids in wastewater followed by UHPLC-MS/MS

Talanta, Journal Year: 2023, Volume and Issue: 264, P. 124752 - 124752

Published: May 31, 2023

Language: Английский

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