CD-MONs,
derived
from
β-cyclodextrin,
possess
notable
hydrophobic
characteristics,
a
considerable
specific
surface
area,
and
remarkable
stability,
rendering
them
highly
advantageous
in
separation
science.
This
research
aimed
to
investigate
the
utility
of
CD-MONs
chromatography
develop
fresh
method
for
fabricating
CD-MON-based
capillary
columns.
Through
monomer-mediated
technique,
we
fabricated
an
innovative
CD-MON
modified
column
application
open-tubular
electrochromatography
(OT-CEC).
The
stationary
phase
on
capillary's
inner
was
analyzed
using
Fourier
transform
infrared
(FT-IR)
spectroscopy
scanning
electron
microscopy
(SEM).
We
assessed
performance
purposes.
microstructure
pronounced
hydrophobicity
contributed
enhanced
selectivity
resolution
separating
diverse
analytes,
such
as
alkylbenzenes,
halogenated
benzenes,
parabens,
polycyclic
aromatic
hydrocarbons
(PAHs).
maximum
efficiency
achieved
1.5
×
105
N/m.
Additionally,
demonstrated
notably
high
capacity,
with
methylbenzene
mass
loading
capacity
up
197.9
pmol,
surpassing
that
previously
reported
porous
materials-based
capillaries.
Furthermore,
this
self-constructed
effectively
utilized
PAH
determination
actual
environmental
water
samples,
exhibiting
spiked
recoveries
ranging
93.2%
107.9%
lake
samples.
These
findings
underscore
potential
effective
Journal of Separation Science,
Journal Year:
2024,
Volume and Issue:
47(2)
Published: Jan. 1, 2024
Designing
advanced
stationary
phases
to
improve
separation
efficiency
is
essential
in
capillary
electrochromatography.
Due
their
outstanding
performance,
covalent
organic
frameworks
have
recently
demonstrated
considerable
promise
the
field
of
science.
Herein,
an
open-tubular
electrochromatography
method
was
reported
using
porous
imine-based
framework
with
sufficiently
available
interaction
sites
as
phase.
The
coated
easily
prepared
via
situ
growth
at
room
temperature,
and
its
performance
evaluated,
indicating
high
for
three
types
analytes,
including
herbicides,
polybrominated
dibenzofurans,
bisphenols.
Moreover,
showed
good
reproducibility
stability,
intraday
(n
=
3),
interday
column-to-column
3)
relative
standard
deviations
retention
time
peak
areas
less
than
5%.
remained
unchanged
even
after
200
runs
maximum
theoretical
plates
reached
up
85
595
N/m
4,4'-ethylidenebisphenol.
It
predicted
that
phase
would
be
a
strong
contender
chromatographic
efficiency.
Journal of Separation Science,
Journal Year:
2025,
Volume and Issue:
48(3)
Published: March 1, 2025
ABSTRACT
Capillary
electrochromatography
(CEC)
has
attracted
significant
attention
and
gained
considerable
recognition
in
the
field
of
separation
science
owing
to
its
excellent
efficiency.
While
numerous
reviews
on
CEC
have
been
published
recent
years,
a
comprehensive
systematic
summary
typical
synthesis
strategies
for
electrochromatographic
stationary
phases
their
state‐of‐the‐art
applications
remains
lacking.
This
review
highlights
advances
(over
past
3
years)
representative
(including
chiral
separation,
microextraction‐coupled
analysis,
metabolomics,
enzyme
food
analysis)
monolithic
open‐tubular
CEC.
The
advantages
limitations
each
methodology
are
critically
analyzed
present
balanced
evaluation.
Additionally,
this
work
outlines
future
prospects
regarding
development
trends
phase
preparation
methods
evolving
Green Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
10, P. 100131 - 100131
Published: July 27, 2024
Nano-scale
separation
techniques
(NSTs)
offer
significant
advantages
in
relation
to
drug
analysis
a
wide
range
of
samples.
NSTs,
including
low
flow
rate
LC
systems
or
capillary
chip
based
electrophoresis/electrochromatography
systems,
have
become
the
primary
tool
for
advanced
analysis,
and
indispensable
technology
sensitive
selective
analysis.
In
recent
decades,
advances
been
achieved
using
NSTs
this
review,
sample
preparation
strategies,
new
applications
contribution
toward
forensic
science
were
reported.
addition,
some
selected
with
without
mass
spectrometry
(e.g.,
resolution/high
resolution
-MS)
are
summarized.
