Advanced Functional Materials,
Journal Year:
2023,
Volume and Issue:
34(6)
Published: Oct. 22, 2023
Abstract
Encapsulation
is
a
promising
technology
to
enhance
the
pharmacokinetic
properties
of
proteins
and
peptides,
particularly
addressing
their
short
half‐life.
Despite
its
potential,
this
method
has
limitations,
such
as
low
encapsulation
efficiency,
minimal
mass
fraction
therapeutic
agents,
potential
loss
biological
activity.
In
study,
pivotal
role
amphiphilic
polymers
in
achieving
efficient
protein
peptide
delved
into.
It
found
that
these
not
only
improve
solvation
cargo
nanoparticles
but
also
form
robust
3D
polymer
layer
at
oil/water
interface.
This
interfacial
barrier
effectively
minimizes
escape
peptides
during
process,
an
impressive
efficiency
up
99.8%
for
agents.
Remarkably,
agents
resultant
microparticles
exceed
59.9
wt.%.
The
prolonged
payload
release
30
days
both
vitro
vivo,
leading
heightened
efficacy
type
2
diabetic
rats.
Furthermore,
required
amount
administration
reduced
by
factor
47.5,
substantially
mitigating
inflammatory
response
injection
site.
conclusion,
findings
highlight
transformative
using
accumulation
encapsulate
peptides.
Advances in Colloid and Interface Science,
Journal Year:
2025,
Volume and Issue:
342, P. 103534 - 103534
Published: April 27, 2025
The
ligand
characteristics
of
polypyridyls,
primarily
bipyridine
(bipy),
phenanthroline
(Phen),
terpyridine
(Tpy),
naphthyridine
(NC),
and
their
derivatives,
are
popular
for
ability
to
create
stable
chelating
complexes
with
metal
ions.
Because
these
characteristics,
they
coordination
have
been
used
many
purposes.
Polypyridyl-based
heterocycles
widely
employed
as
corrosion
inhibitors
in
the
aqueous
phase
provide
long-lasting,
consistent
efficient
protection.
unshared
nitrogen
electron
pairs
polypyridyl-based
significantly
coordinate
substrates.
Corrosion
based
on
polypyridyls
increase
polarization
or
charge
transfer
resistance
(Rp
Rct)
decrease
current
density
(icorr)
by
blocking
active
sites.
Their
adsorption,
coordination,
chelation
thermodynamically
advantageous
due
nature,
which
results
positive
entropy
change
(S
>
0).
They
adhere
several
isotherms
during
adsorption
metallic
surface.
review
article
discusses
inhibition
potential
inhibitors,
mechanism
challenges
opportunities
using
coating
applications
also
surveyed.
significance
complexes,
regioisomerism,
relative
location
atoms
discussed.
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(14), P. 9725 - 9746
Published: Jan. 1, 2024
This
study
entails
the
syntheses
of
a
homopolymer,
poly(diallylammonium
chloride)
(3),
and
copolymers
(8a-c)
containing
hydrophilic/hydrophobic
pendants
their
role
in
mitigating
mild
steel
aggressive
20%
formic
acid,
type
corrosion
that
is
not
frequently
discussed
literature.
The
synthesized
homopolymer
were
characterized
by
FTIR,
NMR,
viscometry,
TGA.
Inhibitor
8b
was
found
to
be
most
potent,
with
81.8%
inhibition
efficiency
(IE)
registered
via
potentiodynamic
polarization
method
for
100
ppm
inhibitor
concentration
at
30
°C.
8b,
mixed
2
mmol
KI,
showed
more
than
90%
IE
meager
1
concentration.
For
synergism
50
reached
high
value
99.1%.
so
good
it
helped
retain
∼100%
its
original
even
after
24
h
weight
loss
60
adsorption
isotherm
followed
Langmuir
adsorbed
chemisorption.
A
very
(2.48
×
105
L
mol-1)
equilibrium
constant
(Kads)
indicated
strong
adsorption.
XPS
SEM
surface
studies
provided
evidence
on
metal
surface.
Some
toxicological
parameters,
such
as
LC50,
bioaccumulation
factor,
developmental
toxicity,
have
been
measured
computationally.
brief
mechanistic
insight
into
how
inhibitors
functioned
has
offered
along
DFT
study.
Lubricants,
Journal Year:
2024,
Volume and Issue:
12(4), P. 135 - 135
Published: April 17, 2024
Cold
rolling
emulsion
contains
a
variety
of
functional
additives,
which
often
exhibit
complex
interactions
with
each
other.
Sodium
alkane
sulfonate
(SAS)
is
common
corrosion
inhibitor
used
in
cold
emulsions
for
temporary
rust
prevention.
In
this
study,
it
was
found
that
SAS
would
deteriorate
the
tribological
properties
emulsion.
Emulsions
containing
and
different
friction
modifiers
were
prepared.
Tribology
tests
carried
out
on
four-ball
wear
tester.
White
light
interferometer
to
investigate
3D
morphology
surface
volume.
Microscopic
surfaces
observed
using
scanning
electron
microscope
(SEM).
The
chemical
activity
electrostatic
potential
molecules
calculated
based
density
theory
(DFT).
adsorption
energies
additives
metal
via
molecular
dynamics
(MD)
simulation.
results
indicate
strong
force
gives
an
advantage
competitive
ester
due
positive
charge
surface.
This
modifier
not
functioning
properly
being
significantly
reduced.
