Polymers, Journal Year: 2024, Volume and Issue: 16(24), P. 3528 - 3528
Published: Dec. 18, 2024
Artificial blood vessels made from polyurethane (PU) have been researched for many years but are not yet in clinical use. The main reason was that the PU materials prone to degradation after contact with and will also cause inflammation long-term implantation. At present, has progress biostability biocompatibility, respectively. artificial still requires a balance between material stability biocompatibility maintain its vivo, which needs be further optimized. Based on requirement of vascular applications, this paper views development biostable PU, bioactive bioresorbable PU. improvement monomer structure, chemical composition, additives discussed improve vivo. surface grafting functionalization methods reduce thrombosis promote endothelialization improving summarized. In addition, tissue-engineered is rate mechanical properties. ideal must good properties, stability, at same time. Finally, application potential prospected.
Language: Английский