Inclisiran in patients with acute ischemic stroke: first data DOI Creative Commons
M. S. Cherepyansky, G. M. Ponomareva, I. B. Skiba

et al.

Kardiologiia, Journal Year: 2023, Volume and Issue: 63(10), P. 39 - 46

Published: Nov. 8, 2023

Aim. To evaluate the effect of inclisiran therapy on parameters lipid metabolism in hospitalized patients with acute ischemic stroke. Material and methods. A prospective, observational, non-randomized study was performed. The included 12 stroke prescribed a combination lipid-lowering (284 mg as single dose). At 15 days after start therapy, changes blood composition were assessed. For quantitative variables, median, maximum minimum values determined. significance differences between related samples variables assessed using Mann-Whitney test. Results. Before total cholesterol (TC) 7.33 mmol/l low-density lipoprotein C (LDL-C) 5.23 mmol/l. TC significantly decreased by 52.1 % LDL-C 71.1 %. proportion who reached goal 66.7 There no adverse events considered investigators to be therapy. Conclusion. strategy early administration (or its statin) allows safe achievement significant reduction already

Language: Английский

Inclisiran in patients with acute ischemic stroke: first data DOI Creative Commons
M. S. Cherepyansky, G. M. Ponomareva, I. B. Skiba

et al.

Kardiologiia, Journal Year: 2023, Volume and Issue: 63(10), P. 39 - 46

Published: Nov. 8, 2023

Aim. To evaluate the effect of inclisiran therapy on parameters lipid metabolism in hospitalized patients with acute ischemic stroke. Material and methods. A prospective, observational, non-randomized study was performed. The included 12 stroke prescribed a combination lipid-lowering (284 mg as single dose). At 15 days after start therapy, changes blood composition were assessed. For quantitative variables, median, maximum minimum values determined. significance differences between related samples variables assessed using Mann-Whitney test. Results. Before total cholesterol (TC) 7.33 mmol/l low-density lipoprotein C (LDL-C) 5.23 mmol/l. TC significantly decreased by 52.1 % LDL-C 71.1 %. proportion who reached goal 66.7 There no adverse events considered investigators to be therapy. Conclusion. strategy early administration (or its statin) allows safe achievement significant reduction already

Language: Английский

Citations

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