PeerJ,
Journal Year:
2023,
Volume and Issue:
11, P. e16119 - e16119
Published: Sept. 28, 2023
The
quest
for
microbial
cellulases
has
intensified
as
a
response
to
global
challenges
in
biofuel
production.
efficient
deconstruction
of
lignocellulosic
biomass
holds
promise
generating
valuable
products
various
industries
such
food,
textile,
and
detergents.
This
article
presents
systematic
bioprospection
aimed
at
isolating
actinomycetes
with
exceptional
cellulose
capabilities.
Our
methodology
explored
the
biodiverse
oligotrophic
region
Cuatro
Cienegas,
Coahuila,
within
Chihuahuan
Desert.
Among
evaluated
collection,
78%
exhibited
cellulolytic
activity.
Through
meticulous
screening
process
based
on
enzymatic
index
evaluation,
we
identified
highly
Streptomyces
strain
further
investigation.
Submerged
fermentation
this
revealed
an
endoglucanase
activity
149
U/mg.
Genomic
analysis
sp.
STCH565-A
unique
configurations
carbohydrate-active
enzyme
(CAZyme)
genes,
underscoring
its
potential
bioconversion
applications.
These
findings
not
only
highlight
significance
Desert
rich
source
microorganisms
but
also
offer
insights
into
exploration
selection
high-performing
application
diverse
environmental
contexts.
In
conclusion,
our
bioprospecting
study
lays
foundation
harnessing
from
Desert,
implications
advancing
processes
industries.
can
serve
blueprint
future
efforts
different
regions,
facilitating
targeted
discovery
cellulosic
Arabian Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
17(6), P. 105777 - 105777
Published: April 5, 2024
Soil
contamination
by
lead,
zinc,
iron,
manganese,
and
copper
is
a
widespread
environmental
issue
associated
with
the
mining
industry.
Primary
sources
include
activities,
production
processing
operations,
waste
disposal
management
practices,
atmospheric
sediments.
degradation,
water
pollution
impacting
aquatic
ecosystems,
plant
absorption
leading
to
agricultural
product
contamination,
health
risks
exposure
copper,
along
effects
on
fauna
biodiversity,
constitute
primary
impacts
of
contamination.
In
this
study,
diverse
sampling
analysis
methods,
geographic
information
systems,
remote
sensing
techniques
are
investigated
for
monitoring
assessing
soil
these
metals.
modification
techniques,
phytoremediation,
other
strategies
reduction
considered
among
most
crucial,
alongside
protection
risk
strategies.
Finally,
article
explores
innovative
methods
solutions
mineral
remediation,
application
green
chemistry
sustainable
practices
in
industry,
utilization
artificial
intelligence
controlling
heavy
metal
ion
pollution.
Environmental Technology & Innovation,
Journal Year:
2024,
Volume and Issue:
34, P. 103625 - 103625
Published: April 4, 2024
Contaminants,
such
as
nucleic
acids
or
toxic
small
molecules,
threaten
both
human
health
and
ecosystems
when
they
infiltrate
the
environment.
The
precise
highly
sensitive
identification
of
contaminants
holds
paramount
importance
across
diverse
domains,
including
safeguarding
food
integrity,
facilitating
clinical
diagnostics,
monitoring
environmental
conditions.
Traditional
methodologies,
encompassing
spectroscopy,
chromatography,
sequencing,
metagenomics,
have
conventionally
served
pivotal
roles
in
detection
processes.
Nevertheless,
these
methods
encountered
recurring
challenges
related
to
sensitivity,
specificity,
portability.
This
review
focuses
on
groundbreaking
CRISPR/Cas12-based
biosensors.
These
biosensors
leverage
incredible
precision
programmability
CRISPR/Cas
system
recognize
specific
targets.
Here,
we
comprehensively
assess
fundamental
mechanisms
that
enable
detection,
ranging
from
guide
RNA
design
collateral
cleavage.
versatility
CRISPR/Cas12
becomes
evident
through
their
applications.
applications
encompass
medical
safety,
monitoring.
transition
conventional
ultimately
represents
a
significant
milestone
contaminant
detection.
By
incorporating
molecular
biology,
nanotechnology,
bioinformatics,
potential
reshape
landscape
water
CRIPSR-Cas
diagnostics
is
transformative
technology
paves
way
for
safer
healthier
future
environment
life.
Cleaner Chemical Engineering,
Journal Year:
2022,
Volume and Issue:
4, P. 100073 - 100073
Published: Oct. 9, 2022
Quality
water
is
used
for
various
daily
chores
like
drainage,
drinking,
sanitation,
agricultural,
and
other
industrial
applications,
thus
being
the
need
of
hour.
Water
a
dominant
raw
material
in
manufacturing
pharmaceuticals
chemicals;
reliable
superior
sources
are
needed
many
processes,
including
cooling,
refining,
extraction.
The
purpose
urban
wastewater
treatment
to
eliminate
contaminants,
destroy
toxicants,
neutralise
coarse
particles,
bacteria
increase
consistency
discharged
maintain
allowable
amount
be
into
or
agricultural
property.
So,
goal
lower
BOD,
COD,
eutrophication,
etc.,
receiving
stop
radioactive
compounds
from
spreading
through
food
chain.
Pharmaceutical
has
wide
range
characteristics,
high
organic
matter,
microbial
contamination,
salt
content,
inability
biodegrade.
Following
secondary
application,
residual
quantities
suspended
solids
dissolved
matter
exist.
Therefore,
advanced
necessary
efficiency
pharmaceutical
effluent.
In
methods
described
this
study,
Advanced
Oxidation
Bioremediation—the
latter
emerges
as
most
environmentally
commercially
viable
option.
This
paper
discusses
types
bioremediations,
their
limits
with
reducing
ecotoxicological
impacts
wastewater.
Advances in medical diagnosis, treatment, and care (AMDTC) book series,
Journal Year:
2023,
Volume and Issue:
unknown, P. 134 - 184
Published: June 16, 2023
The
field
of
drug
discovery
is
continually
advancing
with
the
emergence
new
technologies
and
scientific
developments.
Moreover,
there
a
recent
growing
interest
in
exploiting
natural
products
as
potential
source
novel
leads.
This
chapter
provides
an
overview
current
state
discovery,
specific
focus
on
integrative
medicine.
process
discussed,
including
target
identification,
lead
generation,
optimization,
preclinical
clinical
development,
along
challenges
associated
each
step
solutions.
use
leads
explored,
examples
that
have
been
transformed
into
drugs
efforts
to
discover
product-based
drugs.
Furthermore,
proposes
valuable
insights
opportunities
this
field,
well
solutions
for
discovering
developing
