Role of repeat transurethral resection in no-muscle-invasive bladder tumour: an umbrella review DOI Creative Commons
Qingxin Yu,

Ruicheng Wu,

Zhouting Tuo

et al.

Therapeutic Advances in Medical Oncology, Journal Year: 2024, Volume and Issue: 16

Published: Jan. 1, 2024

Background: Repeat transurethral resection of bladder tumour (reTURB) is a conventional treatment for non-muscle-invasive cancer (NMIBC) to enhance prognosis. However, the necessity reTURB in NMIBC remains controversial owing upstaging treatments and new evidence. Objectives: We performed an umbrella review determine need patients with NMIBC. Design: extracted data from meta-analyses that were screened out after systematic search PubMed, Embase, Web Science Cochrane Database Systematic Reviews. Methods: Risk Bias Reviews Grading Recommendations, Assessment, Development Evaluation tools used assess quality each included meta-analysis outcomes. Results: Our study seven meta-analyses. Two studies assessed efficiency who underwent en bloc tumours (ERBT). Patients ERBT reported low residual rates 5.9% 0.3%, respectively. Conversely, (cTURB) had high rates. cTURB significantly improved 1-year recurrence-free survival (RFS) compared those initial alone. In terms progression-free (PFS), PFS subgroup analyses ERBT, did not affect RFS received ERBT. Currently, only limited number randomised clinical trials have evaluated reTURB, various factors influenced its efficacy. Conclusion: There was significant variation outcomes among undergoing reTURB. The efficacy depend on numerous factors, such as surgical approach, equipment medication usage. eligible may constitute group does require Further are required validate these findings. Registration: This registered International Prospective Register (CRD42023439078).

Language: Английский

Efficiency of transurethral en‐bloc resection vs. conventional transurethral resection for non‐muscle‐invasive bladder cancer: An umbrella review DOI Creative Commons
Dengxiong Li, Qingxin Yu,

Ruicheng Wu

et al.

Cancer Medicine, Journal Year: 2024, Volume and Issue: 13(11)

Published: May 31, 2024

Abstract Background En‐Bloc transurethral resection of bladder tumor (ERBT) was clinically used to resect non‐muscle‐invasive cancer (NMIBC). However, discrepancies persist regarding the comparisons between ERBT and conventional (cTURBT). Methods We conducted a comprehensive search in PubMed, Embase, Web Science, Cochrane Database Systematic Reviews, performed manual searches reference lists collect extract data. Data evaluation carried out using Review Manager 5.4.0, Rx64 4.1.3, relevant packages. Results There were nine eligible meta‐analyses RCTs our study. NMIBC patients undergoing significant associated with lower rate perforation obturator nerve reflex compared those receiving cTURBT. Our pooled result indicated that cTURBT required similar operation time. Regarding postoperative outcomes, demonstrated superior performance terms detrusor muscle presence, catheterization time, residual tumor. exhibited higher three‐month recurrence‐free survival (RFS) ( p < 0.05; I 2 = 0%). In bipolar subgroup, had better 12‐month RFS than Simultaneously, exclusion Hybrid Knife data revealed improvement 50%). Conclusion Using combination umbrella review meta‐analysis, we or comparable perioperative outcome improved 3 12 month suggest maybe surgical method for

Language: Английский

Citations

11
Role of repeat transurethral resection in no-muscle-invasive bladder tumour: an umbrella review DOI Creative Commons
Qingxin Yu,

Ruicheng Wu,

Zhouting Tuo

et al.

Therapeutic Advances in Medical Oncology, Journal Year: 2024, Volume and Issue: 16

Published: Jan. 1, 2024

Background: Repeat transurethral resection of bladder tumour (reTURB) is a conventional treatment for non-muscle-invasive cancer (NMIBC) to enhance prognosis. However, the necessity reTURB in NMIBC remains controversial owing upstaging treatments and new evidence. Objectives: We performed an umbrella review determine need patients with NMIBC. Design: extracted data from meta-analyses that were screened out after systematic search PubMed, Embase, Web Science Cochrane Database Systematic Reviews. Methods: Risk Bias Reviews Grading Recommendations, Assessment, Development Evaluation tools used assess quality each included meta-analysis outcomes. Results: Our study seven meta-analyses. Two studies assessed efficiency who underwent en bloc tumours (ERBT). Patients ERBT reported low residual rates 5.9% 0.3%, respectively. Conversely, (cTURB) had high rates. cTURB significantly improved 1-year recurrence-free survival (RFS) compared those initial alone. In terms progression-free (PFS), PFS subgroup analyses ERBT, did not affect RFS received ERBT. Currently, only limited number randomised clinical trials have evaluated reTURB, various factors influenced its efficacy. Conclusion: There was significant variation outcomes among undergoing reTURB. The efficacy depend on numerous factors, such as surgical approach, equipment medication usage. eligible may constitute group does require Further are required validate these findings. Registration: This registered International Prospective Register (CRD42023439078).

Language: Английский

Citations

1